DK194585D0 - NITROSOUR INGREDIENT DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND MEDICINES CONTAINING THEM - Google Patents

NITROSOUR INGREDIENT DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND MEDICINES CONTAINING THEM

Info

Publication number
DK194585D0
DK194585D0 DK194585A DK194585A DK194585D0 DK 194585 D0 DK194585 D0 DK 194585D0 DK 194585 A DK194585 A DK 194585A DK 194585 A DK194585 A DK 194585A DK 194585 D0 DK194585 D0 DK 194585D0
Authority
DK
Denmark
Prior art keywords
formula
hydrogen
represent
hydrogen atom
group
Prior art date
Application number
DK194585A
Other languages
Danish (da)
Other versions
DK194585A (en
Inventor
Pierre Roger
Patrick Choay
Claude Monneret
Jean-Paul Fournier
Original Assignee
Dropic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dropic filed Critical Dropic
Publication of DK194585D0 publication Critical patent/DK194585D0/en
Publication of DK194585A publication Critical patent/DK194585A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nitrosourea derivatives, process for their preparation and pharmaceutical compositions containing them. The nitrosourea derivatives of the invention correspond to the formula (I), in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an -NR1R2 group, Y represents a hydrogen atom, a hydroxy group or an -NR'1R'2 group, where R1 and/or R'1 each represent a hydrogen atom or formula (II), Hal being a halogen, and R2 and/or R'2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R'' can represent hydrogen or OH, provided that at least, X represents formula (III), with R1 representing formula (IV) or Y represents formula (V) with R'1 representing formula (VI) and provided that, either R' represents hydrogen or R'' represents hydrogen, and R' and R'' cannot be simultaneously hydrogen atoms. These compounds present an antitumor activity.
DK194585A 1983-08-30 1985-04-30 NITROSOUR INGREDIENT DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND MEDICINES CONTAINING THEM DK194585A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8313878A FR2551068B1 (en) 1983-08-30 1983-08-30 NOVEL NITROSOURES DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM
FR8313878 1983-08-30
PCT/EP1984/000260 WO1985001050A1 (en) 1983-08-30 1984-08-29 Nitrosourea derivatives, process for their preparation and medicaments containing them
EP8400260 1984-08-29

Publications (2)

Publication Number Publication Date
DK194585D0 true DK194585D0 (en) 1985-04-30
DK194585A DK194585A (en) 1985-04-30

Family

ID=9291872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK194585A DK194585A (en) 1983-08-30 1985-04-30 NITROSOUR INGREDIENT DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND MEDICINES CONTAINING THEM

Country Status (15)

Country Link
EP (1) EP0143675B1 (en)
JP (1) JPS60502105A (en)
KR (1) KR920001690B1 (en)
AT (1) ATE50264T1 (en)
CA (1) CA1257587A (en)
DE (1) DE3481305D1 (en)
DK (1) DK194585A (en)
ES (1) ES535903A0 (en)
FR (1) FR2551068B1 (en)
GR (1) GR80249B (en)
IL (1) IL72817A (en)
NZ (1) NZ209397A (en)
PT (1) PT79158B (en)
WO (1) WO1985001050A1 (en)
ZA (1) ZA846783B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2614303B1 (en) * 1987-04-22 1990-06-08 Sanofi Sa NITROSOURED DERIVATIVES, THEIR NEW PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATIONS.
FR2614304A1 (en) * 1987-04-22 1988-10-28 Sanofi Sa NITROSOUREES DERIVATIVES, THEIR NEW PREPARATION METHOD AND THERAPEUTIC APPLICATIONS THEREOF.
DE19524515A1 (en) * 1995-07-05 1997-01-09 Deutsches Krebsforsch Saccharide conjugates
WO1998043628A1 (en) * 1997-04-02 1998-10-08 Viktor Veniaminovich Tets Antitumoral drugs (chlonidan)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940383A (en) * 1974-12-12 1976-02-24 Stanford Research Institute Streptozotocin analogs
JPS554324A (en) * 1978-06-26 1980-01-12 Kaken Pharmaceut Co Ltd Novel glycopyranosidoamine derivative, its preparation, and antitumor agent comprising it as active constituent
JPS5681596A (en) * 1979-12-07 1981-07-03 Tokyo Tanabe Co Ltd Glucopyranose-nitrosourea derivative, carcinostatic agent consisting of the same and preparation
JPS57200397A (en) * 1981-06-03 1982-12-08 Akira Kimura Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation

Also Published As

Publication number Publication date
AU580009B2 (en) 1988-12-22
FR2551068B1 (en) 1986-03-21
DE3481305D1 (en) 1990-03-15
CA1257587A (en) 1989-07-18
IL72817A0 (en) 1984-11-30
EP0143675A1 (en) 1985-06-05
ZA846783B (en) 1985-04-24
ES8602031A1 (en) 1985-12-01
GR80249B (en) 1984-12-14
ATE50264T1 (en) 1990-02-15
ES535903A0 (en) 1985-12-01
AU3392684A (en) 1985-03-29
IL72817A (en) 1989-09-10
NZ209397A (en) 1988-04-29
KR920001690B1 (en) 1992-02-22
PT79158B (en) 1986-08-19
WO1985001050A1 (en) 1985-03-14
DK194585A (en) 1985-04-30
PT79158A (en) 1984-09-01
FR2551068A1 (en) 1985-03-01
JPS60502105A (en) 1985-12-05
EP0143675B1 (en) 1990-02-07
KR850700031A (en) 1985-10-21

Similar Documents

Publication Publication Date Title
ES8307806A1 (en) Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them.
MY103850A (en) Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them.
EP0163599A3 (en) Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
IL81002A (en) 3,4-diphenyl-pyrazoline-1-carboxamide derivatives,processes for the preparation thereof and insecticidal and acaricidal compositions containing the same
ES8301927A1 (en) Substituted azobicyclooctanecarboxylic acids, process for their preparation und pharmaceutical compositions containing them.
EP0210753A3 (en) Anti-tumor medicament
EP0219852A3 (en) Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for producing the same
DK194585D0 (en) NITROSOUR INGREDIENT DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND MEDICINES CONTAINING THEM
MY102310A (en) New 5-oxy deravatives of tetrahydrofuran
SE8205867L (en) NEW 4-PHENYL-4-OXO-2-BUTENIC ACID DERIVATIVES, THEIR SALTS, PREPARATION OF THEM, USE THEREOF AS A MEDICINAL PRODUCT AND COMPOSITIONS CONTAINING THEM
ES8103112A1 (en) Pseudotrisaccharides, their preparation and use as medicaments.
FR2381035A1 (en) SUBSTITUTES USEFUL AS MEDICINES AND METHODS FOR THEIR PREPARATION
DE3064485D1 (en) Anthracycline glycosides, process for their preparation and therapeutical composition containing them
ES8207507A1 (en) Platinum compounds having antitumor or antimicrobial activity, and pharmaceutical preparations containing them.
ES8401088A1 (en) Phosphoramide derivatives and medicines containing the same
ES8507136A1 (en) Anthracycline glycosides, their preparation and pharmaceutical preparations containing them.
YU158385A (en) Process for obtaining derivatives of 2-pyridine thioles
WO1987007609A1 (en) 1,1,2-triaryl-1-butene derivatives
ES8800198A1 (en) N-substituted aziridine-2-carboxylic acid derivatives, process for their preparation as well as medicaments containing these substances.
IL75042A0 (en) 2,3-diamino-2,3-didesoxyhexose derivatives,their preparation and pharmaceutical compositions containing them
EP0380669A4 (en) Isoprenoid derivatives and pharmaceutical preparation containing same
ES2000614A6 (en) Complexes of platinum (II) 2,3-dinitrilo-2-butene-2,3-dithiolate, a process for preparing them and pharmaceutical compositions containing them.
ES485333A1 (en) 5,6,7,8-Tetrahydro-4(3H)- quinazolinone derivatives useful as spasmolytics
EP0361510A3 (en) Antitumor substance, process for preparing the same, and anticancer agent containing the same
HUT39731A (en) Process for preparing arphamenine derivatives and pharmaceutical compositions containing such compounds

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment