DK191984A - Hydroxyphenylaminobenzenalkanoler, som antiallergiske midler, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og fremgangsmaade til fremstilling af disse - Google Patents

Hydroxyphenylaminobenzenalkanoler, som antiallergiske midler, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og fremgangsmaade til fremstilling af disse Download PDF

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Publication number
DK191984A
DK191984A DK191984A DK191984A DK191984A DK 191984 A DK191984 A DK 191984A DK 191984 A DK191984 A DK 191984A DK 191984 A DK191984 A DK 191984A DK 191984 A DK191984 A DK 191984A
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Denmark
Prior art keywords
procedures
production
hydroxyphenylaminobenzenal
chanols
intermediates
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DK191984A
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DK191984D0 (da
Inventor
Donald Charles Schlegel
Malcolm Rice Bell
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Sterling Drug Inc
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Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK191984D0 publication Critical patent/DK191984D0/da
Publication of DK191984A publication Critical patent/DK191984A/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C215/76—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring
    • C07C215/82—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the amino groups further bound to a carbon atom of another six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

Forbindelserne fremstilles ved forskellige fremgangsmåder.
Hellemprodukte t
Figure DK191984AD00021
hvori R er H. alkyl, alkoxy eller halogen; R' er H eller alkyl, og R" er H, alkyl eller halogen.
Forbindelserne III fremstilles ved reduktion af
Figure DK191984AD00022
hvori R° er -CH^C^H,., med et me ta 1 nydrid, hvorefter
L O J
en eventuelt fremstillet forbindelse, hvori R' er H, omsættes med alkylhalogenid til fremstilling af en forbindelse, hvori R" er alkyl.
DK191984A 1983-04-18 1984-04-13 Hydroxyphenylaminobenzenalkanoler, som antiallergiske midler, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og fremgangsmaade til fremstilling af disse DK191984A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/485,936 US4496590A (en) 1983-04-18 1983-04-18 Benzyl alcohol derivatives, their preparation and use
US48593683 1983-04-18

Publications (2)

Publication Number Publication Date
DK191984D0 DK191984D0 (da) 1984-04-13
DK191984A true DK191984A (da) 1984-10-19

Family

ID=23929994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK191984A DK191984A (da) 1983-04-18 1984-04-13 Hydroxyphenylaminobenzenalkanoler, som antiallergiske midler, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og fremgangsmaade til fremstilling af disse

Country Status (13)

Country Link
US (1) US4496590A (da)
EP (1) EP0122518A1 (da)
JP (1) JPS6034934A (da)
KR (1) KR840009062A (da)
AU (1) AU2636384A (da)
DK (1) DK191984A (da)
ES (1) ES8602600A1 (da)
FI (1) FI841433A (da)
GR (1) GR79845B (da)
IL (1) IL71419A0 (da)
NO (1) NO841426L (da)
PT (1) PT78381B (da)
ZA (1) ZA842202B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA865090B (en) * 1985-07-22 1988-02-24 Riker Laboratories Inc Substituted di-t-butylphenols
US5237070A (en) * 1985-07-22 1993-08-17 Riker Laboratories, Inc. Substituted DI-t-butylphenols
US4716178A (en) * 1985-07-22 1987-12-29 Riker Laboratories, Inc. Substituted di-t-butylphenols
CA1285951C (en) * 1985-10-28 1991-07-09 Raj N. Misra Naphthalenyl- and quinolinyl-amino substituted phenols
US4843082A (en) * 1986-05-05 1989-06-27 E. R. Squibb & Sons, Inc. 1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof
US4975461A (en) * 1986-06-19 1990-12-04 E. R. Squibb & Sons, Inc. P-aminophenols, derivatives thereof and method of use
JPH0610174B2 (ja) * 1986-09-29 1994-02-09 株式会社大塚製薬工場 アミノフエノ−ル誘導体
US4757078A (en) * 1986-11-28 1988-07-12 E. R. Squibb & Sons, Inc. Cyclic aryl hydroxamic acids, derivatives thereof and method of use as anti-allergy agents
JPS63185924A (ja) * 1987-01-28 1988-08-01 Otsuka Pharmaceut Factory Inc リポキシゲナ−ゼ阻害剤
JPS63185923A (ja) * 1987-01-28 1988-08-01 Otsuka Pharmaceut Factory Inc 抗炎症剤
US7399572B2 (en) * 2005-06-03 2008-07-15 Fujifilm Electronic Materials U.S.A., Inc. Pretreatment compositions
EP3354645A1 (en) * 2017-01-26 2018-08-01 Patheon Austria GmbH & Co KG Process for preparing urolithins
RU2020128799A (ru) 2018-02-27 2022-03-28 Амазентис Са Промышленный синтез уролитина а

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895063A (en) * 1965-04-08 1975-07-15 Ciba Geigy Corp Substituted Anilino Benzyl Alcohols
US3513199A (en) * 1967-05-05 1970-05-19 Smithkline Corp Substituted anilino benzyl alcohols
CH506480A (de) * 1969-02-20 1971-04-30 Ciba Geigy Ag Verfahren zur Herstellung von neuen, substituierten o-Anilino-phenäthylalkoholen
CH527794A (de) * 1970-01-29 1972-09-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen, substituierten o-Anilino-phenäthylalkoholen
US3792090A (en) * 1970-08-06 1974-02-12 Oreal P-hydroxy-diphenylamine compounds
US3884625A (en) * 1970-12-21 1975-05-20 Oreal Indophenols dyes for coloring keratin fibers

Also Published As

Publication number Publication date
EP0122518A1 (en) 1984-10-24
JPS6034934A (ja) 1985-02-22
AU2636384A (en) 1984-10-25
IL71419A0 (en) 1984-06-29
US4496590A (en) 1985-01-29
PT78381A (en) 1984-05-01
ES531550A0 (es) 1985-12-01
DK191984D0 (da) 1984-04-13
ZA842202B (en) 1984-10-31
GR79845B (da) 1984-10-31
ES8602600A1 (es) 1985-12-01
NO841426L (no) 1984-10-19
PT78381B (en) 1986-05-28
KR840009062A (ko) 1984-12-24
FI841433A (fi) 1984-10-19
FI841433A0 (fi) 1984-04-11

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