JPS5686157A - N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation - Google Patents

N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation

Info

Publication number
JPS5686157A
JPS5686157A JP16354579A JP16354579A JPS5686157A JP S5686157 A JPS5686157 A JP S5686157A JP 16354579 A JP16354579 A JP 16354579A JP 16354579 A JP16354579 A JP 16354579A JP S5686157 A JPS5686157 A JP S5686157A
Authority
JP
Japan
Prior art keywords
oxo
isoindolinyl
substituted
butanamide
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16354579A
Other languages
Japanese (ja)
Inventor
Kazuo Kikazawa
Mineji Hiiragi
Haruhide Ishimaru
Toshihisa Nakamura
Keiko Shiroyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Grelan Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grelan Pharmaceutical Co Ltd filed Critical Grelan Pharmaceutical Co Ltd
Priority to JP16354579A priority Critical patent/JPS5686157A/en
Publication of JPS5686157A publication Critical patent/JPS5686157A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An N-substituted-2-oxo-3-[4-( 1-oxo-2-isoindolinyl )-phenyl]butanamide shown by the formula I (R1 and R2 are H, alkyl, aralkyl, aryl, substituted aryl, or R1 and R2 form a heterocyclic compound).
EXAMPLE: N-benzyl-2-oxo-3-[4-(1-oxo-2-isoindolinyl)phenyl]butanamide.
USE: A painkilling antiphlogistic. Having a strong anti-inflammatory action.
PROCESS: A compound shown by the formula II (X is OH, alkoxy, halogen, alkoxycarbonyloxy) is reacted with an amine shown by the formula III to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP16354579A 1979-12-18 1979-12-18 N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation Pending JPS5686157A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16354579A JPS5686157A (en) 1979-12-18 1979-12-18 N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16354579A JPS5686157A (en) 1979-12-18 1979-12-18 N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation

Publications (1)

Publication Number Publication Date
JPS5686157A true JPS5686157A (en) 1981-07-13

Family

ID=15775920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16354579A Pending JPS5686157A (en) 1979-12-18 1979-12-18 N-substituted-2-oxo-3 4- 1-oxo-2-isoindolinyl phenyl butanamide and its preparation

Country Status (1)

Country Link
JP (1) JPS5686157A (en)

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