DK190387A - Vaccine - Google Patents

Vaccine

Info

Publication number
DK190387A
DK190387A DK190387A DK190387A DK190387A DK 190387 A DK190387 A DK 190387A DK 190387 A DK190387 A DK 190387A DK 190387 A DK190387 A DK 190387A DK 190387 A DK190387 A DK 190387A
Authority
DK
Denmark
Prior art keywords
vaccine
saponin
stimulating
antigen
oil
Prior art date
Application number
DK190387A
Other languages
Danish (da)
English (en)
Other versions
DK190387D0 (da
Inventor
Jay Dean Gerber
Original Assignee
Norden Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norden Lab Inc filed Critical Norden Lab Inc
Publication of DK190387D0 publication Critical patent/DK190387D0/da
Publication of DK190387A publication Critical patent/DK190387A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK190387A 1986-04-18 1987-04-13 Vaccine DK190387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/853,797 US4806350A (en) 1986-04-18 1986-04-18 Vaccine formulation

Publications (2)

Publication Number Publication Date
DK190387D0 DK190387D0 (da) 1987-04-13
DK190387A true DK190387A (da) 1987-10-19

Family

ID=25316934

Family Applications (1)

Application Number Title Priority Date Filing Date
DK190387A DK190387A (da) 1986-04-18 1987-04-13 Vaccine

Country Status (12)

Country Link
US (1) US4806350A (pt)
EP (1) EP0242205B1 (pt)
JP (1) JP2515321B2 (pt)
AT (1) ATE95425T1 (pt)
AU (1) AU609667B2 (pt)
CA (1) CA1282003C (pt)
DE (1) DE3787663T2 (pt)
DK (1) DK190387A (pt)
ES (1) ES2059369T3 (pt)
IE (1) IE61233B1 (pt)
PT (1) PT84692B (pt)
ZA (1) ZA872743B (pt)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
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SE8405493D0 (sv) * 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
CA1267087A (en) * 1985-02-14 1990-03-27 Nicolaas Visser Synthetic immunogen
DE3775783D1 (de) * 1986-01-14 1992-02-20 Nederlanden Staat Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung.
US6291228B1 (en) 1988-08-03 2001-09-18 Vericore Limited Vaccine
NZ230747A (en) * 1988-09-30 1992-05-26 Bror Morein Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina
US5721109A (en) * 1989-01-18 1998-02-24 Sawai Pharmaceutical Co., Ltd. Method for diagnosing infection caused by acid-fast bacterium
DE69027112T2 (de) * 1989-01-23 1997-01-09 Auspharm International Ltd 4Th Impfstoffzusammensetzung
HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
ES2136620T3 (es) * 1991-04-19 1999-12-01 Lds Technologies Inc Formulaciones de microemulsiones convertibles.
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
CZ278863B6 (en) * 1992-09-07 1994-07-13 Galena Medicinal preparations with n-methylated cyclic undecapeptides
ES2053402B1 (es) * 1993-01-15 1995-02-01 Hipra Lab Sa Metodo de preparacion de vacunas inactivadas y vacunas vivas adyuvantadas asi como las vacunas obtenidas por dicho metodo.
AU689466B2 (en) * 1993-02-26 1998-04-02 Cambridge Biotech Corporation Methods of inducing immunity to lyme disease and a colorimetric assay for borreliacidal activity of antisera
US5902565A (en) * 1993-12-24 1999-05-11 Csl Limited Spray dried vaccine preparation comprising aluminium adsorbed immunogens
US5739118A (en) * 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5688772A (en) * 1994-08-01 1997-11-18 University Of Saskatchewan Quinoa saponin compositions and methods of use
US5597807A (en) * 1994-08-01 1997-01-28 University Of Saskatchewan Quinoa saponin compositions and methods of use
US5962428A (en) * 1995-03-30 1999-10-05 Apollon, Inc. Compositions and methods for delivery of genetic material
FR2733151B1 (fr) * 1995-04-20 1997-05-23 Seppic Sa Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines
US6117432A (en) * 1995-04-20 2000-09-12 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US6689370B1 (en) 1995-04-20 2004-02-10 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US20010053365A1 (en) * 1995-04-25 2001-12-20 Smithkline Beecham Biologicals S.A. Vaccines
EP0855906B1 (en) 1995-10-17 2008-02-20 Jagotec AG Insoluble drug delivery
WO1997015316A1 (en) * 1995-10-27 1997-05-01 Merck & Co., Inc. Conjugates of gonadotropin releasing hormone
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US6716823B1 (en) 1997-08-13 2004-04-06 The Uab Research Foundation Noninvasive genetic immunization, expression products therefrom, and uses thereof
US20030045492A1 (en) * 1997-08-13 2003-03-06 Tang De-Chu C. Vaccination by topical application of recombinant vectors
US20030125278A1 (en) * 1997-08-13 2003-07-03 Tang De-Chu C. Immunization of animals by topical applications of a salmonella-based vector
US6348450B1 (en) 1997-08-13 2002-02-19 The Uab Research Foundation Noninvasive genetic immunization, expression products therefrom and uses thereof
US6706693B1 (en) 1997-08-13 2004-03-16 The Uab Research Foundation Vaccination by topical application of genetic vectors
ATE435661T1 (de) * 1997-08-29 2009-07-15 Antigenics Inc Adjuvant qs-21 enthaltende zusammensetzungen mit polysorbate oder cyclodextrin als hilfsmittel
GB9718901D0 (en) * 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
US6524592B2 (en) * 1997-10-17 2003-02-25 American Home Products Corporation Veterinary vaccines
AUPP060097A0 (en) 1997-11-28 1998-01-08 Commonwealth Scientific And Industrial Research Organisation Adjuvant system for enhanced response
US20070059327A2 (en) * 1998-01-15 2007-03-15 Wyeth Streptococcus equi compositions and methods of use
CA2320807C (en) * 1998-02-11 2011-01-18 Research Triangle Pharmaceuticals Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
CN1245955C (zh) 1998-05-29 2006-03-22 斯凯伊药品加拿大公司 热保护微粒组合物及其最终蒸汽灭菌的方法
AU759641B2 (en) 1998-08-19 2003-04-17 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
US7939105B2 (en) * 1998-11-20 2011-05-10 Jagotec Ag Process for preparing a rapidly dispersing solid drug dosage form
GB9908885D0 (en) * 1999-04-19 1999-06-16 Smithkline Beecham Biolog Vccine
DE60014076T2 (de) * 1999-04-19 2005-10-13 Glaxosmithkline Biologicals S.A. Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid
US20040009936A1 (en) * 1999-05-03 2004-01-15 Tang De-Chu C. Vaccine and drug delivery by topical application of vectors and vector extracts
CN1174741C (zh) * 1999-09-21 2004-11-10 Rtp药品公司 生物活性物质的表面改性微粒组合物
CN1313080C (zh) 2000-04-20 2007-05-02 斯凯伊药品加拿大公司 改进的水不溶性药物粒子的制备方法
ES2325057T3 (es) 2000-08-31 2009-08-25 Jagotec Ag Particulas molturadas.
TWI354568B (en) * 2000-09-20 2011-12-21 Jagotec Ag Insoluble drug particle compositions with improved
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
US20050019340A1 (en) * 2000-10-18 2005-01-27 Nathalie Garcon Vaccines
CN1273112C (zh) * 2001-02-22 2006-09-06 斯凯伊药品加拿大公司 具有减少进食-禁食作用的贝特-它汀组合
AU2002253085B2 (en) * 2001-02-28 2006-03-09 Intervet International B.V. Injectable water-in-oil emulsions
US20030138434A1 (en) * 2001-08-13 2003-07-24 Campbell Robert L. Agents for enhancing the immune response
US6861410B1 (en) * 2002-03-21 2005-03-01 Chiron Corporation Immunological adjuvant compositions
US20060099219A1 (en) * 2002-04-24 2006-05-11 Universite Libre De Bruxelles Mutated hpv-16e7 polypeptide, pharmaceutical composition comprising it and its preparation process
KR100720213B1 (ko) 2003-04-04 2007-05-21 화이자 프로덕츠 인코포레이티드 미세 유동화된 수중 유적형 유화액 및 백신 조성물
CN101163494A (zh) * 2005-02-23 2008-04-16 Uab研究基金会 烷基糖苷增强的接种
CN101460192A (zh) * 2006-03-30 2009-06-17 恩布里克斯公司 家禽疫苗接种的方法和组合物
JP5731198B2 (ja) * 2007-09-27 2015-06-10 イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. インビボでのポリヌクレオチドの送達のための連続疎水相を含む担体におけるリポソームの使用
US20100209452A1 (en) * 2007-10-03 2010-08-19 Immunovaccine Technologies, Inc Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof
WO2009146523A1 (en) 2008-06-05 2009-12-10 Immunovaccine Technologies Inc. Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance
JP6240077B2 (ja) 2011-10-06 2017-11-29 イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. Tlr2を活性化するか、またはその活性を増加させるアジュバントを含むリポソーム組成物およびその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1503388A (en) * 1975-07-01 1978-03-08 Inverni Della Beffa Spa Pharmaceutically active complexes and pharmaceutical compositions containing them
JPS5428813A (en) * 1977-08-09 1979-03-03 Yuuichi Yamamura Solid preparation containing cell membrane extract substance used as suspension when using same
SE8205892D0 (sv) * 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
EP0142192A1 (en) * 1983-10-22 1985-05-22 Akzo N.V. Preparation of immunogens consisting of antigenic determinates bound to glycoside-containing carriers
SE8405493D0 (sv) * 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
DE3446515A1 (de) * 1984-12-20 1986-06-26 Behringwerke Ag, 3550 Marburg Oeladjuvierte vaccine und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA872743B (en) 1988-04-27
DE3787663D1 (de) 1993-11-11
PT84692A (en) 1987-05-01
CA1282003C (en) 1991-03-26
JP2515321B2 (ja) 1996-07-10
AU7176087A (en) 1987-10-22
IE871003L (en) 1987-10-18
DE3787663T2 (de) 1994-02-17
ES2059369T3 (es) 1994-11-16
AU609667B2 (en) 1991-05-02
DK190387D0 (da) 1987-04-13
EP0242205B1 (en) 1993-10-06
EP0242205A3 (en) 1989-08-02
US4806350A (en) 1989-02-21
EP0242205A2 (en) 1987-10-21
PT84692B (pt) 1989-11-30
ATE95425T1 (de) 1993-10-15
IE61233B1 (en) 1994-10-19
JPS62255436A (ja) 1987-11-07

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment