ATE95425T1 - Impfstofformulierung. - Google Patents
Impfstofformulierung.Info
- Publication number
- ATE95425T1 ATE95425T1 AT87303337T AT87303337T ATE95425T1 AT E95425 T1 ATE95425 T1 AT E95425T1 AT 87303337 T AT87303337 T AT 87303337T AT 87303337 T AT87303337 T AT 87303337T AT E95425 T1 ATE95425 T1 AT E95425T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccine formulation
- vaccine
- saponin
- stimulating
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/853,797 US4806350A (en) | 1986-04-18 | 1986-04-18 | Vaccine formulation |
EP87303337A EP0242205B1 (de) | 1986-04-18 | 1987-04-15 | Impfstofformulierung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE95425T1 true ATE95425T1 (de) | 1993-10-15 |
Family
ID=25316934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87303337T ATE95425T1 (de) | 1986-04-18 | 1987-04-15 | Impfstofformulierung. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4806350A (de) |
EP (1) | EP0242205B1 (de) |
JP (1) | JP2515321B2 (de) |
AT (1) | ATE95425T1 (de) |
AU (1) | AU609667B2 (de) |
CA (1) | CA1282003C (de) |
DE (1) | DE3787663T2 (de) |
DK (1) | DK190387A (de) |
ES (1) | ES2059369T3 (de) |
IE (1) | IE61233B1 (de) |
PT (1) | PT84692B (de) |
ZA (1) | ZA872743B (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8405493D0 (sv) * | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
CA1267087A (en) * | 1985-02-14 | 1990-03-27 | Nicolaas Visser | Synthetic immunogen |
DE3775783D1 (de) * | 1986-01-14 | 1992-02-20 | Nederlanden Staat | Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung. |
US6291228B1 (en) | 1988-08-03 | 2001-09-18 | Vericore Limited | Vaccine |
NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
US5721109A (en) * | 1989-01-18 | 1998-02-24 | Sawai Pharmaceutical Co., Ltd. | Method for diagnosing infection caused by acid-fast bacterium |
DK0454735T3 (da) * | 1989-01-23 | 1996-10-07 | Auspharm Int Ltd | Vaccine sammensætning |
HU212924B (en) * | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
US5246707A (en) * | 1990-04-26 | 1993-09-21 | Haynes Duncan H | Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes |
US5091188A (en) * | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
US5688761A (en) * | 1991-04-19 | 1997-11-18 | Lds Technologies, Inc. | Convertible microemulsion formulations |
ES2136620T3 (es) * | 1991-04-19 | 1999-12-01 | Lds Technologies Inc | Formulaciones de microemulsiones convertibles. |
GB9110808D0 (en) * | 1991-05-17 | 1991-07-10 | Retroscreen Ltd | Aids vaccine and method for its production |
CZ278863B6 (en) * | 1992-09-07 | 1994-07-13 | Galena | Medicinal preparations with n-methylated cyclic undecapeptides |
ES2053402B1 (es) * | 1993-01-15 | 1995-02-01 | Hipra Lab Sa | Metodo de preparacion de vacunas inactivadas y vacunas vivas adyuvantadas asi como las vacunas obtenidas por dicho metodo. |
CA2157004A1 (en) * | 1993-02-26 | 1994-09-01 | Richard T. Coughlin | Methods of inducing immunity to lyme disease and a colorimetric assay for borreliacidal activity of antisera |
US5902565A (en) * | 1993-12-24 | 1999-05-11 | Csl Limited | Spray dried vaccine preparation comprising aluminium adsorbed immunogens |
US5739118A (en) * | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
US5597807A (en) * | 1994-08-01 | 1997-01-28 | University Of Saskatchewan | Quinoa saponin compositions and methods of use |
US5688772A (en) * | 1994-08-01 | 1997-11-18 | University Of Saskatchewan | Quinoa saponin compositions and methods of use |
US5962428A (en) * | 1995-03-30 | 1999-10-05 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
FR2733151B1 (fr) * | 1995-04-20 | 1997-05-23 | Seppic Sa | Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines |
US6689370B1 (en) | 1995-04-20 | 2004-02-10 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
US6117432A (en) * | 1995-04-20 | 2000-09-12 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
US20010053365A1 (en) * | 1995-04-25 | 2001-12-20 | Smithkline Beecham Biologicals S.A. | Vaccines |
AU709262B2 (en) * | 1995-10-17 | 1999-08-26 | Board Of Regents, The University Of Texas System | Insoluble drug delivery |
WO1997015316A1 (en) * | 1995-10-27 | 1997-05-01 | Merck & Co., Inc. | Conjugates of gonadotropin releasing hormone |
US7255877B2 (en) * | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
US20030125278A1 (en) * | 1997-08-13 | 2003-07-03 | Tang De-Chu C. | Immunization of animals by topical applications of a salmonella-based vector |
US6706693B1 (en) | 1997-08-13 | 2004-03-16 | The Uab Research Foundation | Vaccination by topical application of genetic vectors |
US20030045492A1 (en) * | 1997-08-13 | 2003-03-06 | Tang De-Chu C. | Vaccination by topical application of recombinant vectors |
US6716823B1 (en) | 1997-08-13 | 2004-04-06 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom, and uses thereof |
US6348450B1 (en) | 1997-08-13 | 2002-02-19 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom and uses thereof |
EP2050465B1 (de) * | 1997-08-29 | 2014-06-11 | Antigenics Inc. | Zusammensetzungen mit dem Adjuvans QS-21 und Polysorbat oder Cyclodextrin als Hilfsstoff |
GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
US6524592B2 (en) * | 1997-10-17 | 2003-02-25 | American Home Products Corporation | Veterinary vaccines |
AUPP060097A0 (en) | 1997-11-28 | 1998-01-08 | Commonwealth Scientific And Industrial Research Organisation | Adjuvant system for enhanced response |
US20070059327A2 (en) * | 1998-01-15 | 2007-03-15 | Wyeth | Streptococcus equi compositions and methods of use |
WO1999040906A2 (en) * | 1998-02-11 | 1999-08-19 | Research Triangle Pharmaceuticals | Method and composition for treatment of inflammatory conditions |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
ATE259220T1 (de) | 1998-05-29 | 2004-02-15 | Skyepharma Canada Inc | Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben |
US7097849B2 (en) | 1998-08-19 | 2006-08-29 | Jagotec Ag | Injectable aqueous dispersions of propofol |
RU2233654C2 (ru) * | 1998-11-20 | 2004-08-10 | Ртп Фарма Инк. | Диспергируемые стабилизированные фосфолипидом микрочастицы |
GB9908885D0 (en) * | 1999-04-19 | 1999-06-16 | Smithkline Beecham Biolog | Vccine |
IL145982A0 (en) * | 1999-04-19 | 2002-07-25 | Smithkline Beecham Biolog | Vaccines |
US20040009936A1 (en) * | 1999-05-03 | 2004-01-15 | Tang De-Chu C. | Vaccine and drug delivery by topical application of vectors and vector extracts |
IL148685A0 (en) * | 1999-09-21 | 2002-09-12 | Rtp Pharma Inc | Surface modified particulate compositions of biologically active substances |
ES2469642T3 (es) | 2000-04-20 | 2014-06-18 | Jagotec Ag | Procedimiento mejorado para partículas de fármaco insoluble en agua |
US6634576B2 (en) | 2000-08-31 | 2003-10-21 | Rtp Pharma Inc. | Milled particles |
US8586094B2 (en) * | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
ES2372746T3 (es) * | 2000-09-20 | 2012-01-26 | Jagotec Ag | Micropartículas de fibrato estabilizadas. |
ES2377077T3 (es) * | 2000-10-18 | 2012-03-22 | Glaxosmithkline Biologicals S.A. | Vacunas que comprenden al antígeno MAGE unido a un fragmento de proteína D |
WO2002067901A1 (en) * | 2001-02-22 | 2002-09-06 | Skyepharma Canada Inc. | Fibrate-statin combinations with reduced fed-fasted effects |
DK1367997T3 (da) * | 2001-02-28 | 2009-11-30 | Intervet Int Bv | Injicerbare vand-i-olie emulsioner |
US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
BR0309603A (pt) * | 2002-04-24 | 2005-02-15 | Univ Bruxelles | Polipeptìdeo e7 mutado de hpv-16, composição farmacêutica que o compreende e seu processo de preparação |
WO2004087204A2 (en) | 2003-04-04 | 2004-10-14 | Pfizer Products Inc. | Microfluidized oil-in-water emulsions and vaccine compositions |
MX2007010306A (es) * | 2005-02-23 | 2007-09-26 | Uab Research Foundation | Vacunacion mejorada con alquil-glicosido. |
AU2007245198B2 (en) * | 2006-03-30 | 2010-08-12 | Zoetis Services Llc | Methods and compositions for vaccination of poultry |
WO2009039628A1 (en) | 2007-09-27 | 2009-04-02 | Immunovaccine Technologies Inc. | Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo |
US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
JP5715051B2 (ja) | 2008-06-05 | 2015-05-07 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | リポソーム、抗原、ポリヌクレオチド及び疎水性物質の連続相を含む担体を含む組成物 |
JP6240077B2 (ja) | 2011-10-06 | 2017-11-29 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | Tlr2を活性化するか、またはその活性を増加させるアジュバントを含むリポソーム組成物およびその使用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1503388A (en) * | 1975-07-01 | 1978-03-08 | Inverni Della Beffa Spa | Pharmaceutically active complexes and pharmaceutical compositions containing them |
JPS5428813A (en) * | 1977-08-09 | 1979-03-03 | Yuuichi Yamamura | Solid preparation containing cell membrane extract substance used as suspension when using same |
SE8205892D0 (sv) * | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
EP0142193A1 (de) * | 1983-10-22 | 1985-05-22 | Akzo N.V. | Herstellung von Immunogenen bestehend aus an Glykosid enthaltenden Trägern gebundenen Antigenen und/oder antigenen Determinanten |
SE8405493D0 (sv) * | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
DE3446515A1 (de) * | 1984-12-20 | 1986-06-26 | Behringwerke Ag, 3550 Marburg | Oeladjuvierte vaccine und verfahren zu ihrer herstellung |
-
1986
- 1986-04-18 US US06/853,797 patent/US4806350A/en not_active Expired - Lifetime
-
1987
- 1987-04-13 DK DK190387A patent/DK190387A/da not_active Application Discontinuation
- 1987-04-15 ES ES87303337T patent/ES2059369T3/es not_active Expired - Lifetime
- 1987-04-15 PT PT84692A patent/PT84692B/pt not_active IP Right Cessation
- 1987-04-15 DE DE87303337T patent/DE3787663T2/de not_active Expired - Lifetime
- 1987-04-15 EP EP87303337A patent/EP0242205B1/de not_active Expired - Lifetime
- 1987-04-15 AT AT87303337T patent/ATE95425T1/de not_active IP Right Cessation
- 1987-04-16 AU AU71760/87A patent/AU609667B2/en not_active Ceased
- 1987-04-16 JP JP62096109A patent/JP2515321B2/ja not_active Expired - Lifetime
- 1987-04-16 CA CA000534893A patent/CA1282003C/en not_active Expired - Fee Related
- 1987-04-16 IE IE100387A patent/IE61233B1/en not_active IP Right Cessation
- 1987-04-16 ZA ZA872743A patent/ZA872743B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPS62255436A (ja) | 1987-11-07 |
ZA872743B (en) | 1988-04-27 |
PT84692B (pt) | 1989-11-30 |
US4806350A (en) | 1989-02-21 |
AU609667B2 (en) | 1991-05-02 |
PT84692A (en) | 1987-05-01 |
EP0242205B1 (de) | 1993-10-06 |
EP0242205A2 (de) | 1987-10-21 |
IE871003L (en) | 1987-10-18 |
DE3787663D1 (de) | 1993-11-11 |
CA1282003C (en) | 1991-03-26 |
DE3787663T2 (de) | 1994-02-17 |
JP2515321B2 (ja) | 1996-07-10 |
IE61233B1 (en) | 1994-10-19 |
DK190387A (da) | 1987-10-19 |
ES2059369T3 (es) | 1994-11-16 |
DK190387D0 (da) | 1987-04-13 |
AU7176087A (en) | 1987-10-22 |
EP0242205A3 (en) | 1989-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |