DK1888077T3 - Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat - Google Patents

Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat

Info

Publication number
DK1888077T3
DK1888077T3 DK06753787T DK06753787T DK1888077T3 DK 1888077 T3 DK1888077 T3 DK 1888077T3 DK 06753787 T DK06753787 T DK 06753787T DK 06753787 T DK06753787 T DK 06753787T DK 1888077 T3 DK1888077 T3 DK 1888077T3
Authority
DK
Denmark
Prior art keywords
tetrahydrofolate
estrogens
methyl
pharmaceutical composition
composition containing
Prior art date
Application number
DK06753787T
Other languages
Danish (da)
English (en)
Inventor
Kai Strothmann
Gavin Welch Smith
Kristina King
Rudolf Moser
Klaus Pietrzik
Original Assignee
Bayer Schering Pharma Ag
Merck Eprova Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37396913&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1888077(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102005023301A external-priority patent/DE102005023301B4/de
Priority claimed from DE102006016285A external-priority patent/DE102006016285A1/de
Application filed by Bayer Schering Pharma Ag, Merck Eprova Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1888077T3 publication Critical patent/DK1888077T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DK06753787T 2005-05-13 2006-05-15 Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat DK1888077T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005023301A DE102005023301B4 (de) 2005-05-13 2005-05-13 Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat
DE102006016285A DE102006016285A1 (de) 2006-04-03 2006-04-03 Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat
PCT/EP2006/004858 WO2006120035A2 (de) 2005-05-13 2006-05-15 Pharmazeutische zusammensetzung enthaltend gestagene und/oder estrogene und 5-methyl-(6s)-tetrahydrofolat

Publications (1)

Publication Number Publication Date
DK1888077T3 true DK1888077T3 (da) 2009-08-17

Family

ID=37396913

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06753787T DK1888077T3 (da) 2005-05-13 2006-05-15 Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat
DK09075120.7T DK2116249T3 (da) 2005-05-13 2006-05-15 Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09075120.7T DK2116249T3 (da) 2005-05-13 2006-05-15 Farmaceutisk sammensætning indeholdende gestagener og/eller estrogener og 5-methyl-(6S)-tetrahydrofolat

Country Status (37)

Country Link
US (2) US20080160004A1 (enExample)
EP (3) EP2116249B2 (enExample)
JP (2) JP2008540482A (enExample)
KR (2) KR20080028369A (enExample)
CN (2) CN101954083A (enExample)
AR (1) AR054123A1 (enExample)
AT (2) ATE555791T1 (enExample)
AU (1) AU2006245921A1 (enExample)
BR (1) BRPI0611443B8 (enExample)
CA (1) CA2608639C (enExample)
CL (2) CL2009002187A1 (enExample)
CR (1) CR9531A (enExample)
CY (2) CY1109261T1 (enExample)
DE (1) DE502006003617D1 (enExample)
DK (2) DK1888077T3 (enExample)
DO (1) DOP2006000110A (enExample)
EA (2) EA014664B1 (enExample)
EC (1) ECSP078001A (enExample)
ES (2) ES2387525T5 (enExample)
GT (1) GT200600200A (enExample)
HR (1) HRP20090418T1 (enExample)
IL (1) IL187340A (enExample)
MA (1) MA29448B1 (enExample)
MY (1) MY147362A (enExample)
NO (1) NO345807B1 (enExample)
PE (1) PE20061415A1 (enExample)
PL (2) PL1888077T3 (enExample)
PT (2) PT2116249E (enExample)
RS (2) RS52651B (enExample)
SG (1) SG169973A1 (enExample)
SI (2) SI1888077T1 (enExample)
SV (1) SV2008002527A (enExample)
TN (1) TNSN07418A1 (enExample)
TW (1) TWI380820B (enExample)
UY (1) UY29527A1 (enExample)
WO (1) WO2006120035A2 (enExample)
ZA (2) ZA200710811B (enExample)

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LT3310333T (lt) 2015-06-18 2020-06-25 Estetra Sprl Burnoje dirperguojama vaisto formą, turinti estetrolio komponentą
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JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物

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Also Published As

Publication number Publication date
EP2116249B1 (de) 2012-05-02
ES2387525T5 (es) 2024-07-05
ES2325600T3 (es) 2009-09-09
ATE429917T1 (de) 2009-05-15
SV2008002527A (es) 2008-03-27
BRPI0611443B1 (pt) 2020-07-21
NO20076408L (no) 2008-02-12
EA028530B1 (ru) 2017-11-30
MY147362A (en) 2012-11-30
TNSN07418A1 (en) 2009-03-17
TW200711651A (en) 2007-04-01
ATE555791T1 (de) 2012-05-15
HRP20090418T1 (hr) 2009-09-30
CL2010000989A1 (es) 2011-02-18
EP1888077B1 (de) 2009-04-29
KR101598735B1 (ko) 2016-03-02
SI2116249T1 (sl) 2013-02-28
KR20080028369A (ko) 2008-03-31
CA2608639A1 (en) 2006-11-16
EA200702349A1 (ru) 2008-04-28
JP2013166753A (ja) 2013-08-29
EP2116249A1 (de) 2009-11-11
UY29527A1 (es) 2006-12-29
WO2006120035A3 (de) 2007-02-15
ZA200908894B (en) 2025-01-29
ECSP078001A (es) 2008-01-23
RS50972B (sr) 2010-10-31
BRPI0611443B8 (pt) 2021-05-25
DK2116249T3 (da) 2012-08-20
PT1888077E (pt) 2009-07-20
CY1109261T1 (el) 2014-07-02
TWI380820B (zh) 2013-01-01
CA2608639C (en) 2013-04-30
IL187340A (en) 2015-03-31
PE20061415A1 (es) 2007-01-26
CR9531A (es) 2008-02-21
JP5883810B2 (ja) 2016-03-15
PT2116249E (pt) 2012-08-07
KR20140069175A (ko) 2014-06-09
AR054123A1 (es) 2007-06-06
EP1888077A2 (de) 2008-02-20
HK1118729A1 (en) 2009-02-20
IL187340A0 (en) 2011-08-01
CN101198332B (zh) 2012-07-18
PL1888077T3 (pl) 2009-12-31
MA29448B1 (fr) 2008-05-02
NO345807B1 (no) 2021-08-16
US10463666B2 (en) 2019-11-05
PL2116249T3 (pl) 2013-06-28
ES2387525T3 (es) 2012-09-25
CL2009002187A1 (es) 2010-10-01
SI1888077T1 (sl) 2009-10-31
RS52651B (sr) 2013-06-28
EA200901393A1 (ru) 2010-02-26
US20080160004A1 (en) 2008-07-03
BRPI0611443A2 (pt) 2010-09-08
DE502006003617D1 (de) 2009-06-10
SG169973A1 (en) 2011-04-29
CN101198332A (zh) 2008-06-11
CN101954083A (zh) 2011-01-26
DOP2006000110A (es) 2012-06-15
CY1114403T1 (el) 2016-08-31
EA014664B1 (ru) 2010-12-30
WO2006120035A2 (de) 2006-11-16
JP2008540482A (ja) 2008-11-20
GT200600200A (es) 2007-03-23
US20160095860A1 (en) 2016-04-07
AU2006245921A1 (en) 2006-11-16
EP2298307A1 (de) 2011-03-23
ZA200710811B (en) 2012-06-27
EP2116249B2 (de) 2023-04-05

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