DK1874341T3 - Erythrocytter, der indeholder arginin deiminase - Google Patents
Erythrocytter, der indeholder arginin deiminaseInfo
- Publication number
- DK1874341T3 DK1874341T3 DK06744562T DK06744562T DK1874341T3 DK 1874341 T3 DK1874341 T3 DK 1874341T3 DK 06744562 T DK06744562 T DK 06744562T DK 06744562 T DK06744562 T DK 06744562T DK 1874341 T3 DK1874341 T3 DK 1874341T3
- Authority
- DK
- Denmark
- Prior art keywords
- arginine deiminase
- containing arginine
- erythrocytes containing
- erythrocytes
- deiminase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
- C12Y305/03006—Arginine deiminase (3.5.3.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0504122A FR2884717B1 (fr) | 2005-04-25 | 2005-04-25 | Erythrocytes renfermant de l'arginine deiminase |
PCT/IB2006/001004 WO2006114691A1 (en) | 2005-04-25 | 2006-04-25 | Erythrocytes containing arginine deiminase |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1874341T3 true DK1874341T3 (da) | 2009-08-03 |
Family
ID=35787979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06744562T DK1874341T3 (da) | 2005-04-25 | 2006-04-25 | Erythrocytter, der indeholder arginin deiminase |
Country Status (18)
Country | Link |
---|---|
US (2) | US9125876B2 (da) |
EP (1) | EP1874341B1 (da) |
JP (1) | JP5339899B2 (da) |
KR (1) | KR101431650B1 (da) |
CN (1) | CN101163497B (da) |
AT (1) | ATE432711T1 (da) |
AU (1) | AU2006238917C1 (da) |
CA (1) | CA2606420C (da) |
CY (1) | CY1109353T1 (da) |
DE (1) | DE602006007122D1 (da) |
DK (1) | DK1874341T3 (da) |
ES (1) | ES2326549T3 (da) |
FR (1) | FR2884717B1 (da) |
HK (1) | HK1112187A1 (da) |
PL (1) | PL1874341T3 (da) |
PT (1) | PT1874341E (da) |
SI (1) | SI1874341T1 (da) |
WO (1) | WO2006114691A1 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
EP2242507B1 (en) * | 2008-02-13 | 2013-02-20 | Erytech Pharma | Formulation and method for the prevention and treatment of skeletal manifestation of gaucher's disease |
US8815232B2 (en) | 2008-08-26 | 2014-08-26 | Kyon Biotech Ag | Compositions and methods for treating cancer |
FR2940087B1 (fr) | 2008-12-18 | 2011-05-06 | Lab Francais Du Fractionnement | Erythrocytes contenant du facteur viii, preparation et utilisations. |
US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
JP6017422B2 (ja) | 2010-08-10 | 2016-11-02 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) | 赤血球結合療法 |
US9033948B2 (en) * | 2011-04-19 | 2015-05-19 | Fenwel, Inc. | Single collection bag blood collection system, method and apparatus |
FR3005420B1 (fr) * | 2013-05-07 | 2015-09-18 | Erytech Pharma | Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues. |
CA2930665A1 (en) | 2013-11-18 | 2015-05-21 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
FR3017299B1 (fr) | 2014-02-12 | 2018-05-18 | Erytech Pharma | Composition pharmaceutique comprenant des erythrocytes encapsulant une enzyme a plp et son cofacteur |
AU2015233084B2 (en) | 2014-02-21 | 2020-12-17 | Anokion Sa | Glycotargeting therapeutics |
US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
CA2944492A1 (en) | 2014-04-01 | 2015-10-08 | Rubius Therapeutics, Inc. | Methods and compositions for immunomodulation |
US11613759B2 (en) | 2015-09-04 | 2023-03-28 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
SG11201805253SA (en) | 2016-01-11 | 2018-07-30 | Rubius Therapeutics Inc | Compositions and methods related to multimodal therapeutic cell systems for cancer indications |
WO2018232176A1 (en) | 2017-06-16 | 2018-12-20 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
WO2019042628A1 (en) | 2017-08-31 | 2019-03-07 | Erytech Pharma | ARGININE DEIMINASE ENCAPSULATED WITHIN ERYTHROCYTES AND THEIR USE IN THE TREATMENT OF CANCER AND ARGINASE-1 DEFICIENCY |
EP3449935A1 (en) | 2017-08-31 | 2019-03-06 | Erytech Pharma | Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency |
WO2020009740A2 (en) * | 2018-04-25 | 2020-01-09 | Washington University | Compositions and methods of use thereof for treatment of metabolic diseases and related disorders |
US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
EP4149440A1 (en) | 2020-05-11 | 2023-03-22 | Erytech Pharma | Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof |
CN113750232B (zh) * | 2021-09-12 | 2023-06-02 | 重庆医科大学 | 一种巨噬细胞膜包覆精氨酸脱亚胺酶/过氧化氢酶/ir780纳米粒、制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1051382A (da) * | 1900-01-01 | |||
DE2740053A1 (de) * | 1977-09-06 | 1979-05-03 | Klaus Prof Dr Med Gersonde | Verwendung von allosterischen effektoren mit hilfe von lipidvesikeln ueber eine irreversible inkorporierung zwecks verbesserter o tief 2 -entladung des haemoglobins in erythrozyten |
JPH0235081A (ja) | 1988-07-26 | 1990-02-05 | Agency Of Ind Science & Technol | アルギニン・デイミナーゼおよびその用途 |
JPH0253490A (ja) | 1988-08-16 | 1990-02-22 | Agency Of Ind Science & Technol | アルギニン・デイミナーゼ遺伝子 |
DE58908768D1 (de) | 1988-09-30 | 1995-01-26 | Siemens Ag | Verfahren zum synchronisierten Umtasten eines Polarisationszustandes eines optischen Sendesignals eines optischen Übertragungssystems mit Überlagerungsempfang und Vorrichtung zur Durchführung des Verfahrens. |
JP2900279B2 (ja) | 1989-08-02 | 1999-06-02 | 株式会社ジャパンエナジー | 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤 |
FR2678512B1 (fr) * | 1991-07-03 | 1995-06-30 | Novacell | Machine a internaliser. |
JP3004788B2 (ja) | 1991-10-28 | 2000-01-31 | 株式会社ジャパンエナジー | アルギニンデイミナーゼ発現ベクター、形質転換微生物およびアルギニンデイミナーゼの製造法 |
US5372942A (en) | 1992-02-10 | 1994-12-13 | Coriell Institute For Medical Research | Protease K resistant arginine deiminase, its method of preparation and its use as an anti-neoplastic agent |
AU680890B2 (en) * | 1993-03-23 | 1997-08-14 | Cbr Laboratories, Inc. | Method and apparatus for encapsulation of biologically-active substances in cells |
US5804183A (en) | 1997-01-31 | 1998-09-08 | Enzon, Inc. | Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same |
US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
US6183738B1 (en) | 1997-05-12 | 2001-02-06 | Phoenix Pharamacologics, Inc. | Modified arginine deiminase |
KR100406268B1 (ko) | 1999-12-24 | 2003-11-19 | 주식회사 안지오랩 | 아르기닌 디이미네이즈를 유효성분으로 하는 혈관신생에 의한 질환 치료용 조성물 |
WO2002009741A1 (en) | 2000-07-27 | 2002-02-07 | Angiolab, Inc. | The pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis |
CN1518595A (zh) * | 2000-11-28 | 2004-08-04 | 凤凰药理学公司 | 修饰的精氨酸脱亚胺酶 |
EP1599217B1 (en) * | 2002-11-18 | 2014-04-16 | Polaris Group | Methods for inhibiting viral replication in vivo |
WO2005026319A2 (en) * | 2003-08-06 | 2005-03-24 | The Regents Of Teh University Of California | Erythrocytic cells and method for loading solutes |
-
2005
- 2005-04-25 FR FR0504122A patent/FR2884717B1/fr not_active Expired - Fee Related
-
2006
- 2006-04-25 AU AU2006238917A patent/AU2006238917C1/en active Active
- 2006-04-25 ES ES06744562T patent/ES2326549T3/es active Active
- 2006-04-25 CA CA2606420A patent/CA2606420C/en active Active
- 2006-04-25 EP EP06744562A patent/EP1874341B1/en active Active
- 2006-04-25 CN CN2006800137421A patent/CN101163497B/zh active Active
- 2006-04-25 SI SI200630327T patent/SI1874341T1/sl unknown
- 2006-04-25 AT AT06744562T patent/ATE432711T1/de active
- 2006-04-25 PL PL06744562T patent/PL1874341T3/pl unknown
- 2006-04-25 WO PCT/IB2006/001004 patent/WO2006114691A1/en not_active Application Discontinuation
- 2006-04-25 JP JP2008507191A patent/JP5339899B2/ja active Active
- 2006-04-25 PT PT06744562T patent/PT1874341E/pt unknown
- 2006-04-25 DE DE602006007122T patent/DE602006007122D1/de active Active
- 2006-04-25 US US11/912,236 patent/US9125876B2/en active Active
- 2006-04-25 DK DK06744562T patent/DK1874341T3/da active
- 2006-04-25 KR KR1020077027105A patent/KR101431650B1/ko active IP Right Grant
-
2008
- 2008-07-02 HK HK08107313.7A patent/HK1112187A1/xx unknown
-
2009
- 2009-08-28 CY CY20091100903T patent/CY1109353T1/el unknown
-
2015
- 2015-07-31 US US14/815,203 patent/US9968663B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL1874341T3 (pl) | 2009-12-31 |
CN101163497B (zh) | 2012-12-19 |
SI1874341T1 (sl) | 2009-08-31 |
ES2326549T3 (es) | 2009-10-14 |
AU2006238917B2 (en) | 2011-04-07 |
ATE432711T1 (de) | 2009-06-15 |
FR2884717B1 (fr) | 2009-07-03 |
JP5339899B2 (ja) | 2013-11-13 |
EP1874341B1 (en) | 2009-06-03 |
PT1874341E (pt) | 2009-07-21 |
US20080274092A1 (en) | 2008-11-06 |
US9968663B2 (en) | 2018-05-15 |
CN101163497A (zh) | 2008-04-16 |
DE602006007122D1 (de) | 2009-07-16 |
FR2884717A1 (fr) | 2006-10-27 |
HK1112187A1 (en) | 2008-08-29 |
KR20080000678A (ko) | 2008-01-02 |
US20160030532A1 (en) | 2016-02-04 |
EP1874341A1 (en) | 2008-01-09 |
US9125876B2 (en) | 2015-09-08 |
JP2008538761A (ja) | 2008-11-06 |
CA2606420A1 (en) | 2006-11-02 |
CA2606420C (en) | 2015-01-27 |
WO2006114691A1 (en) | 2006-11-02 |
AU2006238917A1 (en) | 2006-11-02 |
AU2006238917C1 (en) | 2011-08-04 |
CY1109353T1 (el) | 2014-07-02 |
KR101431650B1 (ko) | 2014-08-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1874341T3 (da) | Erythrocytter, der indeholder arginin deiminase | |
ATE508190T1 (de) | Mehrfachpromotor-expressionskassetten zurgleichzeitigen zuführung von rnai-agentien | |
BRPI0508470A (pt) | sistema de teste in vitro para prever toleráncia do paciente aos agentes terapêuticos | |
EA200700717A1 (ru) | Сульфонамиды | |
MX2009007421A (es) | Nucleo absorbente que tiene estructura mejorada. | |
MX2009004320A (es) | Inhibidores de serina proteasa tipo tripsina, y su preparacion y uso. | |
MX2010001589A (es) | Nucleo absorbente. | |
EA200900091A1 (ru) | Новые показания к применению прямых ингибиторов тромбина в лечении сердечно-сосудистых заболеваний | |
MX2010005983A (es) | Nucleo absorbente. | |
EA200800357A1 (ru) | Новые фармацевтические соединения | |
AR051765A1 (es) | Compuestos de moleculas conjugadas con una actividad reforzada de absorcion de celulas | |
WO2008054534A3 (en) | Screening systems utilizing rtp801 | |
ATE485261T1 (de) | Salicylsäurederivate | |
MY150745A (en) | Isoserine derivatives for use as coagulation factor ixa inhibitors | |
CY1116840T1 (el) | Χρηση 24-norudca | |
WO2008081094A3 (fr) | Methode de mesure fonctionnelle de l'activite de la thrombomoduline plasmatique | |
CY1113525T1 (el) | Θεραπεια στοχευσης καθεψινης s | |
EA200870058A1 (ru) | Композиции, содержащие остеопонтин крупного рогатого скота, для улучшения процесса заживления ран | |
BRPI0515161A (pt) | substratos enzimáticos derivados de fenoxazinona e seu uso como revelador na detecção de microorganismos com atividade de peptidase | |
HK1137419A1 (en) | Tartrate derivatives for use as coagulation factor ixa inhibitors | |
NO20085412L (no) | Pyrrolidinderivater som har aktivitet ved GLYT1 transportoren | |
Kinoshita | Effects of oxidative stress on vascular function, and the role of anesthetics | |
ATE474567T1 (de) | Kombinationspräparate enthaltend 2- methylthiazolidin-2,4-dicarbonsäure | |
WO2008073634A3 (en) | Compositions and methods for detecting and treating endothelial dysfunction | |
WO2005087216A3 (de) | Behandlung von anämischen zuständen durch inhibierung der erythrozytenapoptose |