DK1868622T3 - Lactic Acid Bacteria For Reducing Mammalian Inflammation - Google Patents

Lactic Acid Bacteria For Reducing Mammalian Inflammation Download PDF

Info

Publication number
DK1868622T3
DK1868622T3 DK06733290.8T DK06733290T DK1868622T3 DK 1868622 T3 DK1868622 T3 DK 1868622T3 DK 06733290 T DK06733290 T DK 06733290T DK 1868622 T3 DK1868622 T3 DK 1868622T3
Authority
DK
Denmark
Prior art keywords
cells
reuteri
inflammation
tnfa
inflammatory
Prior art date
Application number
DK06733290.8T
Other languages
Danish (da)
English (en)
Inventor
Eamonn Connolly
Original Assignee
Biogaia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogaia Ab filed Critical Biogaia Ab
Application granted granted Critical
Publication of DK1868622T3 publication Critical patent/DK1868622T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK06733290.8T 2005-04-15 2006-04-12 Lactic Acid Bacteria For Reducing Mammalian Inflammation DK1868622T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/107,438 US7344867B2 (en) 2005-04-15 2005-04-15 Selection and use of lactic acid bacteria for reducing inflammation in mammals
PCT/SE2006/000434 WO2006110088A1 (en) 2005-04-15 2006-04-12 Selection and use of lactic acid bacteria for reducing inflammation in mammals

Publications (1)

Publication Number Publication Date
DK1868622T3 true DK1868622T3 (en) 2017-01-16

Family

ID=37087291

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06733290.8T DK1868622T3 (en) 2005-04-15 2006-04-12 Lactic Acid Bacteria For Reducing Mammalian Inflammation

Country Status (16)

Country Link
US (2) US7344867B2 (enExample)
EP (1) EP1868622B1 (enExample)
JP (1) JP4740999B2 (enExample)
KR (1) KR101042123B1 (enExample)
CN (1) CN101160134B (enExample)
AU (1) AU2006234793B2 (enExample)
DK (1) DK1868622T3 (enExample)
ES (1) ES2606765T3 (enExample)
HU (1) HUE032297T2 (enExample)
LT (1) LT1868622T (enExample)
MX (1) MX2007012656A (enExample)
PL (1) PL1868622T3 (enExample)
PT (1) PT1868622T (enExample)
RU (1) RU2378370C2 (enExample)
SI (1) SI1868622T1 (enExample)
WO (1) WO2006110088A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254011A1 (en) * 2007-04-11 2008-10-16 Peter Rothschild Use of selected lactic acid bacteria for reducing atherosclerosis
US20110293710A1 (en) 2010-02-02 2011-12-01 Delphine Saulnier Immunomodulatory properties of lactobacillus strains
US8785183B2 (en) * 2010-09-21 2014-07-22 Biogaia Ab Active plastic material in oil
US20130022586A1 (en) * 2011-07-21 2013-01-24 James Versalovic Production and use of bacterial histamine
ES2402014B1 (es) 2011-09-07 2014-02-27 Consejo Superior De Investigaciones Científicas (Csic) Peptido secretado por lactobacillus plantarum con función inmunomoduladora
CA3008794C (en) 2012-03-29 2021-03-16 Therabiome, Llc Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
CN104755091B (zh) 2012-06-04 2020-07-21 生命大地女神有限公司 预防哺乳动物骨质疏松的乳酸杆菌的选择和应用
RU2015140610A (ru) 2013-03-14 2017-04-17 ТЕРАБАЙОМ, ЭлЭлСи Направленная доставка в желудочно-кишечный тракт пробиотических микроорганизмов и/или терапевтических средств
AU2015209763B2 (en) 2014-01-23 2020-12-24 Biogaia Ab Selection of agents modulating gastrointestinal pain
SG11201705479UA (en) * 2015-03-26 2017-10-30 Biogaia Ab Histamine-producing bacterial strains and their use in cancer
US10376563B1 (en) 2016-02-12 2019-08-13 Wisconsin Alumni Research Foundation Methods for systemically delivering polypeptides and microorganisms therefor
FI3442547T3 (fi) 2016-04-15 2023-09-05 Baylor College Medicine Lactobacillus reuteri MM4-1A käytettäväksi autismikirjon häiriöiden hoidossa tai ehkäisyssä
KR102250597B1 (ko) 2017-11-20 2021-05-11 경희대학교 산학협력단 신규 유산균 및 이의 용도
CN110893195B (zh) * 2019-09-30 2023-03-14 内蒙古伊利实业集团股份有限公司 一种具有缓解肠道炎症功能的副干酪乳杆菌et-22
HUE063707T2 (hu) 2019-11-08 2024-01-28 Biogaia Ab Szerotonintermelõ baktériumok
CN114196581B (zh) * 2020-12-16 2023-06-13 江南大学 缓解高尿酸血症的罗伊氏乳杆菌ccfm1132及应用
AU2022318574B2 (en) 2021-07-30 2024-03-21 Helaina, Inc. Methods and compositions for protein synthesis and secretion
CA3228922A1 (en) 2021-10-11 2023-04-20 Ajinomoto Co., Inc. Bacterium modified to express heterologous tat protein
KR102752058B1 (ko) * 2023-08-25 2025-01-13 전남대학교 산학협력단 락토바실러스 루터리 nchbl-005 균주, 사균체 또는 이의 혼합물을 유효 성분으로 포함하는 염증성 질환 예방, 치료 또는 개선용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413960A (en) 1987-05-01 1995-05-09 Biogaia Ab Antibiotic reuterin
US5458875A (en) 1990-06-15 1995-10-17 Biogaia Ab In ovo method for delivering Lactobacillus reuteri to the gastrointestinal tract of poultry
US5534253A (en) * 1995-06-07 1996-07-09 Biogaia Ab Method of treating enteropathogenic bacterial infections in poultry
US5837238A (en) 1996-06-05 1998-11-17 Biogaia Biologics Ab Treatment of diarrhea
US20010049115A1 (en) * 2000-01-17 2001-12-06 Collins John Kevin Vitro model for gastrointestinal inflammation
AU5773600A (en) * 1999-06-30 2001-01-31 Board Of Regents Of The University Of Nebraska, The Method of isolation of regulated virulence determinants from bacterial pathogens
US6953574B2 (en) * 2002-06-21 2005-10-11 Technology Commercialization, Inc. Method for producing a fermented hydrolyzed medium containing microorganisms
US7105336B2 (en) 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US20040208863A1 (en) 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria

Also Published As

Publication number Publication date
CN101160134B (zh) 2012-08-22
RU2007142174A (ru) 2009-05-20
CN101160134A (zh) 2008-04-09
LT1868622T (lt) 2017-01-10
US20080107635A1 (en) 2008-05-08
ES2606765T3 (es) 2017-03-27
EP1868622A1 (en) 2007-12-26
AU2006234793B2 (en) 2010-10-28
JP4740999B2 (ja) 2011-08-03
MX2007012656A (es) 2007-12-13
AU2006234793A1 (en) 2006-10-19
KR101042123B1 (ko) 2011-06-16
PL1868622T3 (pl) 2017-04-28
RU2378370C2 (ru) 2010-01-10
EP1868622B1 (en) 2016-09-28
HUE032297T2 (en) 2017-09-28
KR20070121700A (ko) 2007-12-27
SI1868622T1 (sl) 2017-01-31
EP1868622A4 (en) 2011-11-02
HK1115730A1 (en) 2008-12-05
PT1868622T (pt) 2016-12-29
US7344867B2 (en) 2008-03-18
US20060233775A1 (en) 2006-10-19
WO2006110088A1 (en) 2006-10-19
JP2008538288A (ja) 2008-10-23

Similar Documents

Publication Publication Date Title
US20080107635A1 (en) Selection and use of lactic acid bacteria for reducing inflammation in mammals
Guarner et al. Role of bacteria in experimental colitis
Zhang et al. Alive and dead Lactobacillus rhamnosus GG decrease tumor necrosis factor-α–induced interleukin-8 production in caco-2 cells
CA2676956A1 (en) Product containing inactivated probiotic for children or infants
DK3061458T3 (en) OIL PRODUCT FOR IMPROVED BREAST MILK NUTRITION TO REDUCE THE RISK OF ALLERGY
KR20070110115A (ko) 면역기능 조정제
RU2642320C2 (ru) Пробиотические штаммы для лечения и/или профилактики диареи
WO2009068474A1 (en) Strains of lactobacillus plantarum as probiotics with immunomodulatory specific effect
AU2002347697B2 (en) Method of improving immune function in mammals using lactobacillus reuteri strains
EP1868596B1 (en) Use of lactobacillus rhamnosus gg in combination with a long chain polyunsaturated fatty acid for the treatment, prevention or reduction of systemic inflammation in a formula-fed infant
US20060233752A1 (en) Method for treating or preventing systemic inflammation in formula-fed infants
TW201313240A (zh) 新穎洛德乳酸桿菌菌株及其應用於改善自體免疫疾病之用途
HK1115730B (en) Selection and use of lactic acid bacteria for reducing inflammation in mammals
KR100887822B1 (ko) 락토바실러스 루테리 균주를 이용하여 포유동물에서 면역기능을 향상시키는 방법
McCoy Effects of feeding Lactobacillus reuteri X-18 on blood chemistry and immune parameters in beagle (Canis familiaris) puppies
Adewoyin Immunomodulating Potential of Exopolysaccharide Producing Lactic Acid Bacteria Isolated from Fer-mented Milk Products
KR100887819B1 (ko) 락토바실러스 루테리 균주를 이용하여 포유동물에서 면역 기능을 향상시키는 방법