DK1868599T3 - Antitumor-kombination omfattende substituerede acryloyl-distamycin-derivater og antistoffer, der hæmmer vækstfaktorer og deres receptorer - Google Patents

Antitumor-kombination omfattende substituerede acryloyl-distamycin-derivater og antistoffer, der hæmmer vækstfaktorer og deres receptorer

Info

Publication number
DK1868599T3
DK1868599T3 DK06725409.4T DK06725409T DK1868599T3 DK 1868599 T3 DK1868599 T3 DK 1868599T3 DK 06725409 T DK06725409 T DK 06725409T DK 1868599 T3 DK1868599 T3 DK 1868599T3
Authority
DK
Denmark
Prior art keywords
receptors
antibodies
distamycin derivatives
growth factors
inhibit growth
Prior art date
Application number
DK06725409.4T
Other languages
English (en)
Inventor
Enrico Pesenti
Marina Ciomei
Maria Cristina Geroni
Original Assignee
Nerviano Medical Sciences Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences Srl filed Critical Nerviano Medical Sciences Srl
Application granted granted Critical
Publication of DK1868599T3 publication Critical patent/DK1868599T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
DK06725409.4T 2005-04-08 2006-03-29 Antitumor-kombination omfattende substituerede acryloyl-distamycin-derivater og antistoffer, der hæmmer vækstfaktorer og deres receptorer DK1868599T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05102792 2005-04-08
PCT/EP2006/061153 WO2006108763A1 (en) 2005-04-08 2006-03-29 Antitumor combination comprising substituted acryloyl distamycin derivatives and antibodies inhibiting growth factors or their receptors

Publications (1)

Publication Number Publication Date
DK1868599T3 true DK1868599T3 (da) 2010-02-15

Family

ID=36624474

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06725409.4T DK1868599T3 (da) 2005-04-08 2006-03-29 Antitumor-kombination omfattende substituerede acryloyl-distamycin-derivater og antistoffer, der hæmmer vækstfaktorer og deres receptorer

Country Status (20)

Country Link
US (1) US20090074757A1 (da)
EP (1) EP1868599B1 (da)
JP (1) JP2008534649A (da)
CN (1) CN101141955A (da)
AT (1) ATE447950T1 (da)
AU (1) AU2006233856A1 (da)
BR (1) BRPI0607499A2 (da)
CA (1) CA2598578A1 (da)
CY (1) CY1109782T1 (da)
DE (1) DE602006010349D1 (da)
DK (1) DK1868599T3 (da)
EA (1) EA011574B1 (da)
ES (1) ES2335805T3 (da)
HR (1) HRP20090617T1 (da)
MX (1) MX2007010525A (da)
PL (1) PL1868599T3 (da)
PT (1) PT1868599E (da)
RS (1) RS51231B (da)
SI (1) SI1868599T1 (da)
WO (1) WO2006108763A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013148263A1 (en) * 2012-03-30 2013-10-03 The Regents Of The University Of California Anti-emp2 therapy reduces cancer stem cells
WO2013155346A1 (en) 2012-04-11 2013-10-17 The Regents Of The University Of California Diagnostic tools for response to 6-thiopurine therapy
CN109966499A (zh) * 2019-04-25 2019-07-05 苏州大学 协同增效的抗乳腺癌转移药物组合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5165922A (en) * 1990-05-22 1992-11-24 Bristol-Myers Squibb Company Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy
US6150508A (en) * 1996-03-25 2000-11-21 Northwest Biotherapeutics, Inc. Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
PL371179A1 (en) * 2002-01-02 2005-06-13 Pharmacia Italia S.P.A. Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors
AU2003219102B2 (en) * 2002-04-02 2008-05-08 Nerviano Medical Sciences S.R.L. Combined therapy against tumors comprising subtituted acryloyl distamycin derivatives and radiotherapy

Also Published As

Publication number Publication date
EA200702197A1 (ru) 2008-02-28
PT1868599E (pt) 2010-01-26
SI1868599T1 (sl) 2010-01-29
EA011574B1 (ru) 2009-04-28
HRP20090617T1 (hr) 2009-12-31
PL1868599T3 (pl) 2010-04-30
WO2006108763A1 (en) 2006-10-19
US20090074757A1 (en) 2009-03-19
ES2335805T3 (es) 2010-04-05
BRPI0607499A2 (pt) 2009-06-13
DE602006010349D1 (de) 2009-12-24
CA2598578A1 (en) 2006-10-19
EP1868599B1 (en) 2009-11-11
RS51231B (sr) 2010-12-31
AU2006233856A1 (en) 2006-10-19
JP2008534649A (ja) 2008-08-28
CY1109782T1 (el) 2014-09-10
ATE447950T1 (de) 2009-11-15
EP1868599A1 (en) 2007-12-26
CN101141955A (zh) 2008-03-12
MX2007010525A (es) 2008-01-16

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DK1868599T3 (da) Antitumor-kombination omfattende substituerede acryloyl-distamycin-derivater og antistoffer, der hæmmer vækstfaktorer og deres receptorer