DK185984A - Disubstituerede polymethyleniminer, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem - Google Patents

Disubstituerede polymethyleniminer, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem Download PDF

Info

Publication number
DK185984A
DK185984A DK185984A DK185984A DK185984A DK 185984 A DK185984 A DK 185984A DK 185984 A DK185984 A DK 185984A DK 185984 A DK185984 A DK 185984A DK 185984 A DK185984 A DK 185984A
Authority
DK
Denmark
Prior art keywords
phenyl
oxygen
image
disubstituted
polymethylenimines
Prior art date
Application number
DK185984A
Other languages
English (en)
Other versions
DK185984D0 (da
Inventor
Gilbert Regnier
Alain Dhainaut
Michel Laubie
Jacques Duhault
Francois Roman
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK185984D0 publication Critical patent/DK185984D0/da
Publication of DK185984A publication Critical patent/DK185984A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Description

valgfrit er substitueret med et eller flere halogenatomer eller alkoxy-grupper med fra 1 til 5 carbcnatomer eller en 0-(CH2)m-0-gruppe, hvor m betyder 1, 2 eller 3; en phenyigruppe valgfrit substitueret med et elier flere halogenatomer, er. eller flere alkoxygrupper med fra 1 til 5 carbonatomer, eller en -0-(CK^^-G-gruppe, hvor m betegner 1, 2 eller 3; en furyl-, thienyl-, benzofuryl-, benzothienyl-, benzodioxanyl-eller benzodioxinylgruppe; eller en
Figure DK185984AD00021
hvor R1 oq R2 er ens eller forskellige og hver betegner hydrogen eller 12 alkyl med fra 1 til 6 carbonatomer eller R og R sammen med nitrogenatomet, hvortil de er bundet, danner en pentagonal eller hexagonal heterocyklisk gruppe valgfrit indeholdende oxygen; eller -S02R'', hvor R’* betegner lige eller forgrenet alkyl med fra 1 til 3 carbonatomer eller phenyl.
Disse forbindelser eller deres fysiologisk tolerable salte kan anvendes terapeutisk, anvnlig til behandling af enhver art vævshypoxi.
DK185984A 1983-04-12 1984-04-11 Disubstituerede polymethyleniminer, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem DK185984A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8305904A FR2544315B1 (fr) 1983-04-12 1983-04-12 Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant
FR8305904 1983-04-12

Publications (2)

Publication Number Publication Date
DK185984D0 DK185984D0 (da) 1984-04-11
DK185984A true DK185984A (da) 1984-10-13

Family

ID=9287737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK185984A DK185984A (da) 1983-04-12 1984-04-11 Disubstituerede polymethyleniminer, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem

Country Status (19)

Country Link
US (1) US4593026A (da)
EP (1) EP0122855B1 (da)
JP (1) JPS59196888A (da)
KR (1) KR840009096A (da)
AT (1) ATE28871T1 (da)
AU (1) AU560621B2 (da)
CA (1) CA1227204A (da)
DE (1) DE3465306D1 (da)
DK (1) DK185984A (da)
ES (1) ES531572A0 (da)
FR (1) FR2544315B1 (da)
GR (1) GR81936B (da)
IL (1) IL71503A (da)
NO (1) NO159018C (da)
NZ (1) NZ207820A (da)
OA (1) OA07703A (da)
PH (1) PH19660A (da)
PT (1) PT78410B (da)
ZA (1) ZA842686B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024617D0 (en) * 1989-12-05 1991-01-02 Ici Plc Heterocyclic compounds
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
FR2667243B1 (fr) * 1990-09-27 1994-11-04 Adir Utilisation de s derives de la triazine et de la pyrimidine pour l'obtention de medicaments reversant la resistance aux agents anticancereux et antimalariques.
FR2673627B1 (fr) * 1991-03-07 1993-05-07 Adir Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
AU676315B2 (en) * 1993-06-30 1997-03-06 Takeda Chemical Industries Ltd. Stabilized solid pharmaceutical preparation and method of producing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1256513A (da) * 1968-10-02 1971-12-08
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
JPS59196888A (ja) 1984-11-08
IL71503A0 (en) 1984-07-31
PT78410A (fr) 1984-05-01
OA07703A (fr) 1985-08-30
PH19660A (en) 1986-06-09
KR840009096A (ko) 1984-12-24
ZA842686B (en) 1985-02-27
NO841451L (no) 1984-10-15
EP0122855A1 (fr) 1984-10-24
FR2544315B1 (fr) 1985-07-05
IL71503A (en) 1987-11-30
DE3465306D1 (en) 1987-09-17
FR2544315A1 (fr) 1984-10-19
NO159018B (no) 1988-08-15
NZ207820A (en) 1986-11-12
CA1227204A (fr) 1987-09-22
PT78410B (fr) 1986-07-17
DK185984D0 (da) 1984-04-11
ES8603457A1 (es) 1985-12-16
AU2684984A (en) 1984-10-18
US4593026A (en) 1986-06-03
AU560621B2 (en) 1987-04-09
ATE28871T1 (de) 1987-08-15
NO159018C (no) 1988-11-23
ES531572A0 (es) 1985-12-16
GR81936B (da) 1984-12-12
EP0122855B1 (fr) 1987-08-12

Similar Documents

Publication Publication Date Title
ES539658A0 (es) Procedimiento de preparacion de nuevos derivados de la xan- tina y de sus sales de adicion con acidos apropiados
DK342883D0 (da) Fremgangsmade til fremstilling af xantinderivater
ATE16805T1 (de) Trifluoromethylphenyltetrahydropyridine mit appetithemmender wirkung, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES528175A0 (es) Procedimiento para la preparacion de nuevas 1,4-dihidropiridinas sustituidas
DK185984A (da) Disubstituerede polymethyleniminer, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem
ZA85390B (en) Methylenediphosphonic acid derivatives,process for their preparation and antirheumatic pharmaceutical compositions in which they are present
ES511574A0 (es) Procedimiento para la obtencion de derivados de benzodioxol.
AR018632A1 (es) Compuestos derivados de acido 1,2,3,4-tetrahidroquinolin-2-carboxilico, su uso en la fabricacion de medicamentos, composicion farmaceutica que los contiene, proceso para su preparacion.
ATE116647T1 (de) Thiophenderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
SE8205867D0 (sv) Noveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation leur application comme medicaments et les compositions les renfermant
MX4767E (es) Procedimiento para la preparacion de derivados del 1,8-etano-5-oxo octa y decahidroquinolinas
NO166321C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridinforbindelser.
DE3866292D1 (de) Piperazinylalkylpiperazindion-derivate, ihre verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DK106287A (da) Glycero-3(2)-phospho-l-serin-derivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og farmaceutiske praeparater indeholdende disse
DK290086D0 (da) I 17-stillingen substituerede sparteinderivater og deres anvendelse som laegemidler
RU2006121328A (ru) Новые пиперидинзамещенные индолы или их гетеропроизводные
ATE5586T1 (de) Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
PT88234A (pt) Processo para a preparacao de derivados de cloroanilina
RU94021690A (ru) Производные бензанилида, способ их получения и фармацевтическая композиция

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment