DE3465306D1 - Disubstituted piperidines, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Disubstituted piperidines, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3465306D1
DE3465306D1 DE8484400712T DE3465306T DE3465306D1 DE 3465306 D1 DE3465306 D1 DE 3465306D1 DE 8484400712 T DE8484400712 T DE 8484400712T DE 3465306 T DE3465306 T DE 3465306T DE 3465306 D1 DE3465306 D1 DE 3465306D1
Authority
DE
Germany
Prior art keywords
phenyl
oxygen
image
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484400712T
Other languages
English (en)
Inventor
Gilbert Regnier
Alain Dhainaut
Michel Laubie
Jacques Duhault
Francois Roman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE3465306D1 publication Critical patent/DE3465306D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8484400712T 1983-04-12 1984-04-11 Disubstituted piperidines, processes for their preparation and pharmaceutical compositions containing them Expired DE3465306D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8305904A FR2544315B1 (fr) 1983-04-12 1983-04-12 Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
DE3465306D1 true DE3465306D1 (en) 1987-09-17

Family

ID=9287737

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484400712T Expired DE3465306D1 (en) 1983-04-12 1984-04-11 Disubstituted piperidines, processes for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4593026A (de)
EP (1) EP0122855B1 (de)
JP (1) JPS59196888A (de)
KR (1) KR840009096A (de)
AT (1) ATE28871T1 (de)
AU (1) AU560621B2 (de)
CA (1) CA1227204A (de)
DE (1) DE3465306D1 (de)
DK (1) DK185984A (de)
ES (1) ES8603457A1 (de)
FR (1) FR2544315B1 (de)
GR (1) GR81936B (de)
IL (1) IL71503A (de)
NO (1) NO159018C (de)
NZ (1) NZ207820A (de)
OA (1) OA07703A (de)
PH (1) PH19660A (de)
PT (1) PT78410B (de)
ZA (1) ZA842686B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024617D0 (en) * 1989-12-05 1991-01-02 Ici Plc Heterocyclic compounds
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
FR2667243B1 (fr) * 1990-09-27 1994-11-04 Adir Utilisation de s derives de la triazine et de la pyrimidine pour l'obtention de medicaments reversant la resistance aux agents anticancereux et antimalariques.
FR2673627B1 (fr) * 1991-03-07 1993-05-07 Adir Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
AU676315B2 (en) * 1993-06-30 1997-03-06 Takeda Chemical Industries Ltd. Stabilized solid pharmaceutical preparation and method of producing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1256513A (de) * 1968-10-02 1971-12-08
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
PT78410A (fr) 1984-05-01
ZA842686B (en) 1985-02-27
FR2544315A1 (fr) 1984-10-19
IL71503A0 (en) 1984-07-31
EP0122855B1 (de) 1987-08-12
PT78410B (fr) 1986-07-17
JPS59196888A (ja) 1984-11-08
IL71503A (en) 1987-11-30
NO159018C (no) 1988-11-23
OA07703A (fr) 1985-08-30
US4593026A (en) 1986-06-03
DK185984A (da) 1984-10-13
EP0122855A1 (de) 1984-10-24
AU560621B2 (en) 1987-04-09
GR81936B (de) 1984-12-12
NO159018B (no) 1988-08-15
FR2544315B1 (fr) 1985-07-05
ES531572A0 (es) 1985-12-16
CA1227204A (fr) 1987-09-22
NZ207820A (en) 1986-11-12
NO841451L (no) 1984-10-15
KR840009096A (ko) 1984-12-24
ES8603457A1 (es) 1985-12-16
PH19660A (en) 1986-06-09
ATE28871T1 (de) 1987-08-15
DK185984D0 (da) 1984-04-11
AU2684984A (en) 1984-10-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee