DK1857451T3 - Fremgangsmåde til fremstilling af en intermediær nyttig til asymmetrisk syntese af (+) - Google Patents

Fremgangsmåde til fremstilling af en intermediær nyttig til asymmetrisk syntese af (+)

Info

Publication number
DK1857451T3
DK1857451T3 DK06009313.5T DK06009313T DK1857451T3 DK 1857451 T3 DK1857451 T3 DK 1857451T3 DK 06009313 T DK06009313 T DK 06009313T DK 1857451 T3 DK1857451 T3 DK 1857451T3
Authority
DK
Denmark
Prior art keywords
duloxetine
methyl
preparing
acid
asymmetric synthesis
Prior art date
Application number
DK06009313.5T
Other languages
English (en)
Inventor
Andrea Poggiali
Francesco Pizzocaro
Paolo Tubertini
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Application granted granted Critical
Publication of DK1857451T3 publication Critical patent/DK1857451T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
DK06009313.5T 2006-05-05 2006-05-05 Fremgangsmåde til fremstilling af en intermediær nyttig til asymmetrisk syntese af (+) DK1857451T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06009313A EP1857451B1 (en) 2006-05-05 2006-05-05 A process for the preparation of an intermediate useful for the asymmetric synthesis of (+)duloxetine

Publications (1)

Publication Number Publication Date
DK1857451T3 true DK1857451T3 (da) 2010-10-11

Family

ID=36609435

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06009313.5T DK1857451T3 (da) 2006-05-05 2006-05-05 Fremgangsmåde til fremstilling af en intermediær nyttig til asymmetrisk syntese af (+)

Country Status (9)

Country Link
EP (1) EP1857451B1 (da)
AT (1) ATE474832T1 (da)
CY (1) CY1110740T1 (da)
DE (1) DE602006015617D1 (da)
DK (1) DK1857451T3 (da)
ES (1) ES2349047T3 (da)
PL (1) PL1857451T3 (da)
PT (1) PT1857451E (da)
SI (1) SI1857451T1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362279B2 (en) 2006-01-06 2013-01-29 Msn Laboratories Limited Process for pure duloxetine hydrochloride

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956388A (en) 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
GB0229583D0 (en) 2002-12-19 2003-01-22 Cipla Ltd A process for preparing duloxetine and intermediates for use therein
JP2006079738A (ja) 2004-09-10 2006-03-23 Matsushita Electric Ind Co Ltd ディスク装置
CZ297560B6 (cs) 2004-10-26 2007-02-07 Zentiva, A. S. Zpusob výroby hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu (duloxetinu)

Also Published As

Publication number Publication date
CY1110740T1 (el) 2012-05-23
SI1857451T1 (sl) 2010-11-30
ES2349047T3 (es) 2010-12-22
DE602006015617D1 (de) 2010-09-02
PT1857451E (pt) 2010-10-25
PL1857451T3 (pl) 2010-12-31
EP1857451A1 (en) 2007-11-21
EP1857451B1 (en) 2010-07-21
ATE474832T1 (de) 2010-08-15

Similar Documents

Publication Publication Date Title
WO2011154433A3 (en) Pesticidal mixtures including isoxazoline derivatives
CY1116498T1 (el) Διεργασια για την παρασκευη (r)-(-)-3-(καρβαμοϋλομεθυλ)-5-μεθυλεξανοϊκου οξεος και πρεγκαμπαλινης και συνθεση ενδιαμεσων
WO2011154434A3 (en) Pesticidal mixtures including isoxazoline derivatives
ATE537136T1 (de) Neues verfahren zur herstellung von säurechloriden
WO2009141362A3 (en) Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
ATE453622T1 (de) Verfahren zur herstellung von enantiomeren angereicherten cyclischen beta-aryl- oder heteroarylcarbonsäuren
ATE515496T1 (de) Verfahren zur herstellung von enantiomerenangereicherter indolin-2-carbonsäure
NZ588894A (en) Process for preparing (s)-pregabalin by chiral resolution
ATE526312T1 (de) Verfahren zur herstellung von reinen 4- pyrrolidinophenylbenzyletherderivaten als maob- inhibitoren
DE602006021355D1 (de) Ein Verfahren zur Herstellung von Tolterodin
WO2012093411A3 (en) Process for the preparation of r-(-)-3- (carbamoylmethyl)-5-methylhexanoic acid and the intermediates
DE602004022337D1 (de) Verfahren zur herstellung von pyridinylmethyl-1h-benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere
WO2011033366A3 (en) Process for the preparation of duloxetine hydrochloride and its precursors
DK1857451T3 (da) Fremgangsmåde til fremstilling af en intermediær nyttig til asymmetrisk syntese af (+)
MX2009011858A (es) Composiciones de (-)-e-10-oh-nt y metodos para su sintesis y uso.
ATE466003T1 (de) Herstellung von 2-aminothiazol-5- carbonsäurederivaten
TW200700369A (en) Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation field of the invention
WO2008107911A3 (en) Novel process for preparation of duloxetine hydrochloride
LT1881953T (lt) Praturtintos karboksirūgščių kompozicijos gavimo būdas
DE602007010926D1 (de) Neues verfahren zur herstellung von ammoniumsalzen von esomeprazol
ATE415388T1 (de) Verfahren zur herstellung von enantiomerenreinen 4-pyrrolidinophenyl- benzyletherderivaten
HK1144192A1 (en) Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester (r)-3--345- 1-[222]
WO2009087674A3 (en) Improved process for the preparation of (s)-pregabalin
WO2008004191A3 (en) Process for the preparation of enantiomerically pure salts of n-methyl-3- ( 1-naphthaleneoxy) -3- (2-thienyl) propanamine
ATE529382T1 (de) Verbessertes verfahren zur herstellung von blausäure