DK1844135T3 - Escherichia-stamme der kan omdanne xmp til gmp og opretholde den inaktiverede tilstand af gen(er) associeret med gmp-nedbrydning og fremgangsmåder til anvendelse deraf - Google Patents

Escherichia-stamme der kan omdanne xmp til gmp og opretholde den inaktiverede tilstand af gen(er) associeret med gmp-nedbrydning og fremgangsmåder til anvendelse deraf

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Publication number
DK1844135T3
DK1844135T3 DK06702908.2T DK06702908T DK1844135T3 DK 1844135 T3 DK1844135 T3 DK 1844135T3 DK 06702908 T DK06702908 T DK 06702908T DK 1844135 T3 DK1844135 T3 DK 1844135T3
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DK
Denmark
Prior art keywords
gmp
gen
escherichia
trials
procedures
Prior art date
Application number
DK06702908.2T
Other languages
Danish (da)
English (en)
Inventor
Young-Hoon Park
Hyoung-Suk Kim
Ki-Hoon Oh
Jeong-Hwan Kim
Yoon-Suk Oh
Jae-Ick Sim
Kyung-Oh Choi
Jin-Nam Lee
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Application granted granted Critical
Publication of DK1844135T3 publication Critical patent/DK1844135T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/32Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
DK06702908.2T 2005-01-21 2006-01-20 Escherichia-stamme der kan omdanne xmp til gmp og opretholde den inaktiverede tilstand af gen(er) associeret med gmp-nedbrydning og fremgangsmåder til anvendelse deraf DK1844135T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020050005863A KR100664653B1 (ko) 2005-01-21 2005-01-21 Xmp를 gmp로 전환시킬 수 있으면서도, gmp의분해에 관련되는 유전자가 불활성화되어 있는 대장균변이주 및 그를 이용하는 방법
PCT/KR2006/000221 WO2006078132A1 (en) 2005-01-21 2006-01-20 Escherichia strain capable of converting xmp to gmp and maintaining the inactivated state of gene(s) associated with gmp degradation and methods of using the same

Publications (1)

Publication Number Publication Date
DK1844135T3 true DK1844135T3 (da) 2014-01-20

Family

ID=36692473

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06702908.2T DK1844135T3 (da) 2005-01-21 2006-01-20 Escherichia-stamme der kan omdanne xmp til gmp og opretholde den inaktiverede tilstand af gen(er) associeret med gmp-nedbrydning og fremgangsmåder til anvendelse deraf

Country Status (9)

Country Link
US (1) US7741101B2 (de)
EP (1) EP1844135B1 (de)
JP (1) JP4769255B2 (de)
KR (1) KR100664653B1 (de)
CN (1) CN101137743B (de)
DK (1) DK1844135T3 (de)
ES (1) ES2443099T3 (de)
TW (1) TW200637909A (de)
WO (1) WO2006078132A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100686561B1 (ko) * 2005-11-25 2007-02-26 씨제이 주식회사 Gmp 저분해 활성을 갖는 코리네박테리움 암모니아게네스cjxcv19 kccm-10692p 및 변이주의 고속선별방법
KR101072720B1 (ko) * 2008-12-17 2011-10-11 씨제이제일제당 (주) 5'-구아닐산 생산능이 향상된 미생물 및 이를 이용한 5'-구아닐산의 생산방법
JP5636648B2 (ja) * 2009-08-10 2014-12-10 味の素株式会社 5’−グアニル酸の製造法
JP7111878B1 (ja) 2021-10-27 2022-08-02 旭化成ファーマ株式会社 ニコチンアミドモノヌクレオチドの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100697551B1 (ko) * 1997-07-18 2007-03-21 아지노모토 가부시키가이샤 발효에 의한 퓨린 뉴클레오사이드의 제조 방법
KR100498897B1 (ko) * 1998-12-16 2005-09-12 씨제이 주식회사 핵산분해능이 약화되고 단백질합성능이 강화된 대장균 변이주
ES2272378T3 (es) * 2000-07-05 2007-05-01 Ajinomoto Co., Inc. Metodo para la produccion de nucleotidos por fermentacion.
JP4696404B2 (ja) * 2000-07-05 2011-06-08 味の素株式会社 発酵法によるヌクレオチドの製造法
KR100547586B1 (ko) * 2003-12-19 2006-01-31 씨제이 주식회사 ushA 유전자가 불활성화된 재조합 에스케리키아속 미생물 및 이를 이용한 5'-구아닐산 합성효소를 배지 중에 축적시키는 방법

Also Published As

Publication number Publication date
CN101137743A (zh) 2008-03-05
ES2443099T3 (es) 2014-02-17
US7741101B2 (en) 2010-06-22
KR100664653B1 (ko) 2007-01-04
WO2006078132A1 (en) 2006-07-27
EP1844135A1 (de) 2007-10-17
JP4769255B2 (ja) 2011-09-07
EP1844135B1 (de) 2013-12-25
EP1844135A4 (de) 2009-04-15
JP2008543272A (ja) 2008-12-04
CN101137743B (zh) 2010-12-08
TW200637909A (en) 2006-11-01
US20080299620A1 (en) 2008-12-04
KR20060084994A (ko) 2006-07-26

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