DK181790D0 - Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider - Google Patents
Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptiderInfo
- Publication number
- DK181790D0 DK181790D0 DK181790A DK181790A DK181790D0 DK 181790 D0 DK181790 D0 DK 181790D0 DK 181790 A DK181790 A DK 181790A DK 181790 A DK181790 A DK 181790A DK 181790 D0 DK181790 D0 DK 181790D0
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- polypeptides
- norleucin
- regulating
- content
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 230000001105 regulatory effect Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 abstract 4
- 230000004151 fermentation Effects 0.000 abstract 4
- LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 3
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 108010006025 bovine growth hormone Proteins 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15727588A | 1988-02-17 | 1988-02-17 | |
| PCT/US1989/000425 WO1989007651A2 (en) | 1988-02-17 | 1989-02-07 | Methods for controlling norleucine content in polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK181790A DK181790A (da) | 1990-07-30 |
| DK181790D0 true DK181790D0 (da) | 1990-07-30 |
Family
ID=22563048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK181790A DK181790D0 (da) | 1988-02-17 | 1990-07-30 | Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP0401254B1 (da) |
| JP (1) | JP2879063B2 (da) |
| AT (1) | ATE152176T1 (da) |
| AU (1) | AU3058489A (da) |
| DE (1) | DE68927997T2 (da) |
| DK (1) | DK181790D0 (da) |
| WO (1) | WO1989007651A2 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60139196D1 (de) | 2000-05-10 | 2009-08-20 | Asubio Pharma Co Ltd | Verfahren zur hemmung der bildung von nebenprodukten bei der herstellung von genetisch modifizierten polypeptiden |
| EP1702074B1 (en) | 2003-09-25 | 2009-11-11 | Monsanto Technology LLC | Prevention of incorporation of non-standard amino acids into protein |
| RU2315807C2 (ru) * | 2004-09-10 | 2008-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ НОРЛЕЙЦИНА И НОРВАЛИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ РОДА Escherichia, В КОТОРОЙ ВСЕ СИНТАЗЫ АЦЕТОГИДРОКСИКИСЛОТ ИНАКТИВИРОВАНЫ |
| JP6479661B2 (ja) * | 2012-09-19 | 2019-03-06 | ジェネンテック， インコーポレイテッド | タンパク質へのノルロイシン誤取り込みを防ぐための方法及び組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443545A (en) * | 1980-08-25 | 1984-04-17 | Massachusetts Institute Of Technology | Process for producing heparinase |
| US5037806A (en) * | 1985-02-22 | 1991-08-06 | Monsanto Company | Biologically active method using somatotropins |
| US4762784A (en) * | 1985-07-15 | 1988-08-09 | International Minerals & Chemical Corp. | Fermemtation process for the high level production of bovine growth hormone |
-
1989
- 1989-02-07 AT AT89902468T patent/ATE152176T1/de active
- 1989-02-07 AU AU30584/89A patent/AU3058489A/en not_active Abandoned
- 1989-02-07 EP EP89902468A patent/EP0401254B1/en not_active Revoked
- 1989-02-07 DE DE68927997T patent/DE68927997T2/de not_active Revoked
- 1989-02-07 EP EP96104679A patent/EP0737752A3/en not_active Ceased
- 1989-02-07 WO PCT/US1989/000425 patent/WO1989007651A2/en not_active Application Discontinuation
- 1989-02-07 JP JP1502300A patent/JP2879063B2/ja not_active Expired - Lifetime
-
1990
- 1990-07-30 DK DK181790A patent/DK181790D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0401254A1 (en) | 1990-12-12 |
| JPH03502758A (ja) | 1991-06-27 |
| WO1989007651A3 (en) | 1989-11-02 |
| JP2879063B2 (ja) | 1999-04-05 |
| EP0401254B1 (en) | 1997-04-23 |
| EP0737752A2 (en) | 1996-10-16 |
| DE68927997D1 (de) | 1997-05-28 |
| DE68927997T2 (de) | 1997-09-11 |
| DK181790A (da) | 1990-07-30 |
| EP0737752A3 (en) | 1996-10-23 |
| WO1989007651A2 (en) | 1989-08-24 |
| ATE152176T1 (de) | 1997-05-15 |
| AU3058489A (en) | 1989-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |