DK176435B1 - Fungicide preparation based on two compounds of the triazole type and method of combating or preventing fungal infestation on culture plants - Google Patents
Fungicide preparation based on two compounds of the triazole type and method of combating or preventing fungal infestation on culture plants Download PDFInfo
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- DK176435B1 DK176435B1 DK199700869A DK86997A DK176435B1 DK 176435 B1 DK176435 B1 DK 176435B1 DK 199700869 A DK199700869 A DK 199700869A DK 86997 A DK86997 A DK 86997A DK 176435 B1 DK176435 B1 DK 176435B1
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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Description
DK 176435 B1DK 176435 B1
Den foreliggende opfindelse angår et fungicidt præparat, som er anvendeligt til behandling af svampeangreb på kulturplanter, på basis af bromuconazol og en anden triazolforbindelse. Opfindelsen angår ligeledes en fremgangsmåde til behandling af kulturplanter med samme formål.The present invention relates to a fungicidal composition useful in the treatment of fungal infestations on culture plants, based on bromuconazole and another triazole compound. The invention also relates to a method for treating cultivated plants for the same purpose.
5 Det er kendt, at bromuconazol er effektivt til bekæmpelse af knækkefodssyge i kornarter. Denne sygdom, som skyldes svampen Pseudocercosporella herpotri-choides, er årsag til betydelige skader, først og fremmest på vinterkornarter. Imidlertid er effektiviteten af bromuconazol ved bekæmpelse af visse andre kornsygdomme og især brunrust (en sygdom, som skyldes svampen Puccinia recondita) og septoriose 10 (en sygdom, som skyldes svampen Septoria tritici) utilstrækkelig, især når udbringningen af det aktive stof gennemføres i det såkaldte “sidste bladbehandlings”-stadium.5 It is known that bromuconazole is effective in controlling crack foot disease in cereals. This disease, caused by the fungus Pseudocercosporella herpotri-choides, is the cause of significant damage, primarily in winter cereals. However, the efficacy of bromuconazole in the control of certain other cereal diseases and in particular brown rust (a disease caused by the fungus Puccinia recondita) and septoriosis 10 (a disease caused by the fungus Septoria tritici) is insufficient, especially when the active substance application is carried out in the so-called “Last leaf processing” stage.
Ved dette udtryk forstås, at den agrokemiske behandling gennemføres, når kornarterne har nået udviklingsstadiet svarende til udviklingen af det sidste blad på stænglen.By this term, it is understood that the agrochemical treatment is carried out when the grains have reached the stage of development corresponding to the development of the last leaf on the stem.
Især bør stabiliteten af bromuconazol forbedres. Ved stabilitet forstås det tidsrum, i 15 hvilket det agrokemiske produkt er i stand til at udøve sin aktivitet.In particular, the stability of bromuconazole should be improved. Stability is defined as the period of time during which the agrochemical product is able to exert its activity.
Især fra Pesticide Manual, 10. udgave, af Clive Tomlin, publiceret af British Crop Protection Council og Royal Society of Chemistry, kendes effektiviteten af visse triazoler, såsom tebuconazol, ved bekæmpelsen af rust og septorioser hos kornarter.Particularly from the Pesticide Manual, 10th edition, by Clive Tomlin, published by the British Crop Protection Council and the Royal Society of Chemistry, the effectiveness of certain triazoles, such as tebuconazole, in the control of rust and septoriosis in cereals is known.
Det er imidlertid stadig ønskeligt at forbedre denne effektivitet, især under 20 formindskelse af den nødvendige dosis af tebuconazol til bekæmpelse af denne sygdom eller også under forøgelse af valgmulighederne, som gives landbrugeren, således at denne kan finde den løsning, som er bedst tilpasset til et bestemt problem.However, it is still desirable to improve this efficacy, in particular by reducing the necessary dose of tebuconazole to combat this disease or also by increasing the options given to the farmer so that he can find the solution that best fits a particular problem.
Et formål med opfindelsen er således at tilvejebringe et nyt fungicidt præparat, som er anvendeligt til løsning af det ovenfor anførte problem.Thus, an object of the invention is to provide a new fungicidal composition which is useful in solving the above problem.
25 Et andet formål med opfindelsen er at foreslå et nyt fungicidt præparat inde holdende bromuconazol, som er anvendeligt ved behandling af brunrust og/eller septorioser i kornarter og/eller akssygdomme (fusarioser), især i hvede.Another object of the invention is to propose a novel fungicidal composition containing bromuconazole which is useful in the treatment of brown rust and / or septoriosis in cereals and / or axillary diseases (fusariosis), especially in wheat.
Et andet formål med opfindelsen er at foreslå et nyt fungicidt præparat indeholdende bromuconazol, som har en forbedret stabilitet.Another object of the invention is to propose a novel fungicidal composition containing bromuconazole which has improved stability.
30 Det har nu vist sig, at disse formål kan opfyldes helt eller delvis med det fun gicide præparat ifølge den foreliggende opfindelse.It has now been found that these objects can be fulfilled in whole or in part with the fungicidal composition of the present invention.
Det fungicide præparat ifølge opfindelsen er karakteriseret ved, at det indeholder bromuconazol (B) og en anden triazol (A) valgt blandt tebuconazol og epoxico-nazol.The fungicidal composition of the invention is characterized in that it contains bromuconazole (B) and another triazole (A) selected from tebuconazole and epoxyconazole.
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Bromuconazol og den ovenfor anførte triazol (A) er aktive stoffer, som er velkendte af fagmanden, og som er beskrevet i “The Pesticide Manual”, 10. udgave, af Clive Tomlin, publiceret af British Crop Protection Council.Bromuconazole and the triazole (A) listed above are active substances well known to those skilled in the art and described in "The Pesticide Manual", 10th Edition, by Clive Tomlin, published by the British Crop Protection Council.
Vægtforholdet B/A i præparatet ifølge opfindelsen er i almindelighed mellem 5 0,1 og 20, fortrinsvis mellem 0,5 og 10. Præparatet ifølge opfindelsen er fordelagtigt på grund af aktivitetsspektret og de lave doser, der kan anvendes af de aktive stoffer, idet det sidstnævnte er særligt vigtigt af letforståelige økologiske grunde. Der kan således med præparatet ifølge opfindelsen observeres bemærkelsesværdige synergistiske virkninger. Disse synergistiske virkninger er især påvist ved anvendelse af meto-10 den ifølge Tammes, "Isoboles, a graphic representation of synergism in pesticides”, Netherlands Journal of Plant Pathology, 70 (1964), s. 73-80.The weight ratio B / A of the composition according to the invention is generally between 0.1 and 20, preferably between 0.5 and 10. The composition of the invention is advantageous because of the activity spectrum and the low doses which can be used by the active substances, the latter is especially important for easy to understand ecological reasons. Thus, with the composition of the invention, remarkable synergistic effects can be observed. These synergistic effects have been particularly demonstrated using the method of Tammes, "Isoboles, a graphic representation of synergism in pesticides", Netherlands Journal of Plant Pathology, 70 (1964), pp. 73-80.
Ifølge en foretrukken variant af præparatet ifølge opfindelsen er triazolen A tebuconazol. I dette tilfælde er vægtforholdet B/A fordelagtigt mellem 0,5 og 5, fortrinsvis mellem 1 og 3.According to a preferred variant of the composition of the invention, the triazole A is tebuconazole. In this case, the weight ratio B / A is advantageously between 0.5 and 5, preferably between 1 and 3.
15 Det fungicide præparat ifølge opfindelsen indeholder sædvanligvis 0,05-95% af blandingen af bromuconazol og triazolen A.The fungicidal composition of the invention usually contains 0.05-95% of the mixture of bromuconazole and triazole A.
Der kan være tale om et koncentreret præparat, dvs. et handelsprodukt, hvori de to aktive stoffer er kombineret. Der kan ligeledes være tale om et fortyndet præparat, som er parat til at blive forstøvet på kulturplanterne, som skal behandles. I det 20 sidstnævnte tilfælde kan fortyndingen med vand enten gennemføres ud fra et koncentreret handelspræparat indeholdende de to aktive stoffer (denne blanding betegnes “anvendelsesklar blanding" eller også “ready mix" på engelsk) eller også ved blanding på stedet (på engelsk betegnet “tank mix”) af to koncentrerede handelspræparater, som hver især indeholder et aktivt stof.It may be a concentrated preparation, ie. a commercial product in which the two active substances are combined. It may also be a diluted preparation ready to be sprayed on the culture plants to be treated. In the latter 20 case, the dilution with water can be effected either from a concentrated commercial preparation containing the two active substances (this mixture is called "ready mix" or also "ready mix" in English) or also by on-site mixture (in English) mix ”) of two concentrated commercial preparations, each containing an active substance.
25 Præparatet ifølge opfindelsen kan desuden indeholde alle sædvanlige tilsæt ningsstoffer eller hjælpestoffer i plantebeskyttelsesmidler, især bærestoffer, overflade-aktive stoffer, vedhæftning s midler og flydemidler.The composition of the invention may additionally contain all the usual additives or excipients in plant protection agents, especially carriers, surfactants, adhesives and flow agents.
Med udtrykket “bærestof' menes i den foreliggende beskrivelse et organisk eller uorganisk, naturligt eller syntetisk materiale, som de aktive stoffer kombineres 30 med for at lette deres udbringning på planterne. Denne bærer er således i almindelighed indifferent, og den bør være landbrugsmæssigt acceptabel, især med hensyn til de behandlede planter. Bærestoffet kan være fast (lerarter, naturlige eller syntetiske silikater, siliciumdioxid, harpikser, voksarter, faste gødningsstoffer osv.) eller flydende (vand, alkoholer, ketoner, jordoliefraktioner, aromatiske eller paraffiniske carbonhydri-35 der, chlorerede carbonhydrider, fortættede gasser osv.).By the term "carrier" in the present specification is meant an organic or inorganic, natural or synthetic material with which the active substances are combined to facilitate their application to the plants. Thus, this carrier is generally inert and should be agriculturally acceptable, especially with regard to the treated plants. The carrier may be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, etc.) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, etc.). .
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Det overfladeaktive middel kan være en emulgator, et dispergeringsmiddel eller et befugtningsmiddel af ionisk eller ikke-ionisk type. Der kan f.eks. nævnes salte af polyacrylsyrer, salte af lignosulfonsyrer, salte af phenolsulfon- eller naphthalensul-fonsyrer, polykondensater af ethylenoxid med fedtalkoholer eller fedtsyrer eller fede 5 aminer, substituerede phenoler (især alkylphenoler eller arylphenoler), salte af estere af sulforavsyrer, derivater af taurin (især alkyltaurater), phosphorsyreestere af polyoxyethylerede alkoholer eller phenoler. Tilstedeværelsen af mindst ét overfladeaktivt middel er ønskelig for at fremme dispergeringen af de aktive stoffer i vand og en god udbringning af disse på planterne.The surfactant may be an emulsifier, dispersant or wetting agent of ionic or nonionic type. For example, are mentioned salts of polyacrylic acids, salts of lignosulfonic acids, salts of phenolsulfonic or naphthalenesulfonic acids, polycondensates of ethylene oxide with fatty alcohols or fatty acids or fatty amines, substituted phenols (especially alkylphenols or arylphenols), salts of esters of sulforates alkyl taurates), phosphoric acid esters of polyoxyethylated alcohols or phenols. The presence of at least one surfactant is desirable in order to promote the dispersion of the active substances in water and a good application thereof on the plants.
10 Dette præparat kan også indeholde enhver art af andre bestanddele, f.eks.This composition may also contain any kind of other constituents, e.g.
beskyttelseskolloider, klæbestoffer, fortykningsmidler, thixotropimidler, penetreringsmidler, stabilisatorer, sekvestreringsmidler, pigmenter, farvestoffer og polymerer.protective colloids, adhesives, thickeners, thixotropic agents, penetrating agents, stabilizers, sequestering agents, pigments, dyes and polymers.
Mere generelt kan præparatet ifølge opfindelsen indeholde alle de faste eller flydende tilsætningsstoffer, som er almindeligt anvendt ved formuleringen af plantebe-15 skyttelsesprodukter.More generally, the composition of the invention may contain all the solid or liquid additives commonly used in the formulation of plant protection products.
Præparatet ifølge opfindelsen kan have fast, gelagtig eller flydende form, og det kan i det sidstnævnte tilfælde være i form af opløsninger, suspensioner, emulsioner eller emulgerbare koncentrater. De flydende præparater foretrækkes, både på grund af deres bekvemme anvendelse og på grund af deres simple fremstilling.The composition of the invention may be of solid, gelled or liquid form and in the latter case it may be in the form of solutions, suspensions, emulsions or emulsifiable concentrates. The liquid preparations are preferred, both because of their convenient application and because of their simple preparation.
20 Som faste præparatformer kan der nævnes pulvere til pudring eller disperge- ring (med et indhold af aktive forbindelser på op til 100%), befugtelige pulvere og granulater til tør udbringning samt dispergerbare eller opløselige granulater.As solid formulations, powders or dispersants (containing up to 100% active compounds), wettable powders and granules for dry application, as well as dispersible or soluble granules can be mentioned.
Befugtelige pulvere (eller pulvere til forstøvning) indeholder ligesom dispergerbare granulater sædvanligvis 20-95% aktive stoffer, og ud over det faste bærestof 25 0-5% af et befugtningsmiddel, 3-10% af et dispergeringsmiddel og om fornødent 0-10% af én eller flere stabilisatorer og/eller andre tilsætningsstoffer, såsom pigmenter, farvestoffer, penetreringsmidler, klæbestoffer eller antiklumpningsmidler, farvestoffer osv. Det vil forstås, at visse af disse præparater, såsom befugtelige pulvere eller dispergerbare granulater, er beregnet til at danne flydende præparater ved an-30 vendeisen.Wettable powders (or powders for atomization), like dispersible granules, usually contain 20-95% of active ingredients, and in addition to the solid carrier 25 0-5% of a wetting agent, 3-10% of a dispersant and, if necessary, 0-10% of one or more stabilizers and / or other additives, such as pigments, dyes, penetrants, adhesives or antifouling agents, dyes, etc. It will be understood that certain of these preparations, such as wettable powders or dispersible granules, are intended to form liquid preparations upon application. -30 turnaround.
Som flydende præparatformer kan der nævnes opløsninger, især vandopløselige koncentrater, emulgerbare koncentrater, emulsioner, koncentrerede suspensioner, aerosoler og pastaer.Liquid formulations include solutions, especially water-soluble concentrates, emulsifiable concentrates, emulsions, concentrated suspensions, aerosols and pastes.
De emulgerbare eller opløselige koncentrater indeholder oftest 10-80% aktive 35 stoffer, og de anvendelsesklare emulsioner eller opløsninger indeholder 0,01-20% ak- 4 DK 176435 B1 tive stoffer. Ud over opløsningsmidlet kan de emulgerbare koncentrater om fornødent indeholde 2-20% af passende tilsætningsstoffer, såsom stabilisatorer, overfladeaktive midler, penetreringsmidler, korrosionsinhibitorer, farvestoffer eller klæbestoffer som nævnt ovenfor. Ud fra disse koncentrater kan der ved fortynding med vand dannes 5 emulsioner med enhver ønsket koncentration, som især er egnede til påføring på de overjordiske dele af planten, som skal behandles. Som allerede anført er de vandige dispersioner og emulsioner, f.eks. præparater opnået ved fortynding med vand af et befugteligt pulver eller et emulgerbart koncentrat ifølge opfindelsen, omfattet af den foreliggende opfindelse. Emulsionerne kan være af vand-i-olie-typen eller olie-i-vand-10 typen, og de kan have en tyk konsistens, ligesom mayonnaise.The emulsifiable or soluble concentrates most often contain 10-80% of active substances and the ready-to-use emulsions or solutions contain 0.01-20% of active substances. In addition to the solvent, the emulsifiable concentrates may contain, if necessary, 2-20% of suitable additives such as stabilizers, surfactants, penetrants, corrosion inhibitors, dyes or adhesives as mentioned above. From these concentrates, by diluting with water, 5 emulsions can be formed with any desired concentration which is particularly suitable for application to the above-ground parts of the plant to be treated. As already stated, the aqueous dispersions and emulsions, e.g. compositions obtained by diluting with water a wettable powder or an emulsifiable concentrate according to the invention, within the scope of the present invention. The emulsions may be water-in-oil or oil-in-water type and may have a thick consistency, such as mayonnaise.
De koncentrerede suspensioner, som ligeledes kan anvendes til forstøvning, er stabile flydende produkter, som ikke fortykkes eller danner et bundfald ved oplagring, og de indeholder sædvanligvis 10-75% aktive stoffer, 0,5-15% overfladeaktive midler, 0,1-10% thixotropimidler og 0-10% passende tilsætningsstoffer, såsom pig-15 menter, farvestoffer, skumdæmpende midler, korrosionsinhibitorer, stabilisatorer, penetreringsmidler og klæbestoffer og, som bærestof, vand eller en organisk væske, hvori de aktive stoffer er tungtopløselige eller uopløselige. Visse faste organiske stoffer eller uorganiske salte kan være opløst i bærestoffet for at bidrage til at forhindre bundfældning eller som midler til at forhindre, at vandet fryser.The concentrated suspensions, which can also be used for atomization, are stable liquid products which do not thicken or precipitate upon storage and usually contain 10-75% of active substances, 0.5-15% of surfactants, 0.1- 10% thixotropic agents and 0-10% suitable additives such as pigments, dyes, antifoaming agents, corrosion inhibitors, stabilizers, penetrating agents and adhesives and, as a carrier, water or an organic liquid wherein the active substances are heavily soluble or insoluble. Certain solid organics or inorganic salts may be dissolved in the carrier to help prevent precipitation or as means to prevent water from freezing.
20 Præparatet ifølge opfindelsen fremstilles ifølge i og for sig kendte metoder.The composition of the invention is prepared according to methods known per se.
Til fremstilling af pulvere til forstøvning eller befugtelige pulvere blandes de aktive stoffer således intimt i passende blandere med de yderligere stoffer, og der formales i møller eller andre formalingsapparater. Der fås derved pulvere til forstøvning, hvis befugtelighed og suspenderbarhed er fordelagtig. De kan suspenderes med vand 25 i enhver ønsket koncentration, og suspensionerne er meget fordelagtige at anvende, især til påføring på de overjordiske dele af planter.Thus, for the preparation of powders for atomization or wettable powders, the active substances are intimately mixed in suitable mixers with the additional substances and milled in mills or other grinding apparatus. Thus, powders are provided for atomization, the wettability and suspendability of which is advantageous. They can be suspended with water 25 at any desired concentration and the suspensions are very advantageous to use, especially for application to the above-ground parts of plants.
I stedet for befugtelige pulvere kan der fremstilles pastaer eller koncentrerede suspensioner. Der anvendes lignende betingelser og nærmere omstændigheder med hensyn til fremstilling og anvendelse af disse pastaer som for befugtelige pulvere eller 30 pulvere til forstøvning, idet en del af den nødvendige formalingsproces blot gennemføres i flydende medium.Instead of wettable powders, pastes or concentrated suspensions can be prepared. Similar conditions and conditions for the preparation and use of these pastes are used as for wettable powders or powders for atomization, part of the necessary grinding process being carried out only in liquid medium.
De dispergerbare granulater fremstilles sædvanligvis ved agglomerering eller ekstrudering eller komprimering i egnede granuleringssystemer af præparater af den befugtelige pulver-type. Granulater til tør udbringning fås sædvanligvis ved imprægne-35 ring af et granuleret bærestof med en opløsning eller emulsion af de aktive stoffer.The dispersible granules are usually prepared by agglomeration or extrusion or compression in suitable granulation systems of wettable powder type preparations. Dry application granules are usually obtained by impregnating a granulated carrier with a solution or emulsion of the active substances.
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Opfindelsen angår endelig også en behandlingsfremgangsmåde, som er beregnet til at bekæmpe eller forebygge svampeangreb på kulturplanter, og som er karakteriseret ved, at der på planternes overjordiske dele påføres en effektiv og ikke-fytotoksisk dosis af et præparat ifølge opfindelsen.Finally, the invention also relates to a method of treatment intended to control or prevent fungal infestation on cultured plants, characterized in that an effective and non-phytotoxic dose of a composition according to the invention is applied to the plants' soil.
5 Dette præparat anvendes fordelagtigt således, at den anvendte dosis af bromuconazol er mellem 100 og 300 g/ha, fortrinsvis mellem 150 og 250 g/ha, og dosen af triazol A er mellem 50 og 250 g/ha, fortrinsvis mellem 75 og 200 g/ha. Denne dosis er afhængig af sygdommens natur, de behandlede planters udviklingsstadie, angrebsgraden og de klimatiske forhold.This composition is advantageously used such that the dose of bromuconazole used is between 100 and 300 g / ha, preferably between 150 and 250 g / ha, and the dose of triazole A is between 50 and 250 g / ha, preferably between 75 and 200 g / ha. This dose depends on the nature of the disease, the stage of development of the treated plants, the degree of attack and the climatic conditions.
10 Når forbindelse A ifølge en foretrukken variant af præparatet ifølge opfindel sen er tebuconazol, er dosen af tebuconazol mellem 75 og 250 g/ha, fortrinsvis mellem 100 og 150 g/ha.When compound A of a preferred variant of the composition of the invention is tebuconazole, the dose of tebuconazole is between 75 and 250 g / ha, preferably between 100 and 150 g / ha.
Svampeangrebene er først og fremmest sådanne forårsaget af septorioser (Septoria tritici, Septoria nodorum), rust (Puccinia striiformis, Puccinia recondita) og 15 aks-fusarioser (Fusarium culmorum, Microdochium nivale).The fungal attacks are primarily those caused by septoroses (Septoria tritici, Septoria nodorum), rust (Puccinia striiformis, Puccinia recondita) and 15 ax fusarioses (Fusarium culmorum, Microdochium nivale).
Afgrøder, som egner sig til behandlingsfremgangsmåden ifølge opfindelsen, er kornarter, især byg, hvede, rug og triticale, fortrinsvis hvede.Crops suitable for the process of the invention are cereals, especially barley, wheat, rye and triticale, preferably wheat.
De følgende eksempler tjener til at illustrere de fordelagtige egenskaber af præparaterne ifølge opfindelsen.The following examples serve to illustrate the advantageous properties of the compositions of the invention.
20 I de vedføjede tegningsfigurer er dosen af hvert aktivt stof, som er nødvendig til at kontrollere den fytopatogene svamp på det anførte niveau, sammenlignet med dosen af de to aktive stoffer i blanding. Den effektive dosis af hvert aktivt stof taget isoleret er anført på abscissen og ordinaten, og der er trukket en ret linie, som skærer disse to akser og forbinder disse to doser. Hvad angår de to aktive stoffer taget som 25 blanding, er dosen af blandingen ved et givet forhold anført ved et punkt.In the accompanying drawings, the dose of each active substance required to control the phytopathogenic fungus at the indicated level is compared to the dose of the two active substances in admixture. The effective dose of each active substance taken in isolation is indicated on the abscissa and ordinate, and a straight line is drawn which intersects these two axes and connects these two doses. For the two active substances taken as a mixture, the dose of the mixture at a given ratio is indicated at one point.
6 DK 176435 B16 DK 176435 B1
Eksempel 1: Forsøg under glas med et præparat indeholdende en blanding af bromuconazol og tebuconazol på Puccinia recondita, som er ansvarlig for brunrust hos hvede.Example 1: Test under glass with a composition containing a mixture of bromuconazole and tebuconazole on Puccinia recondita, which is responsible for brown rust in wheat.
Der anvendes enten et præparat indeholdende bromuconazol i form af en 5 koncentreret suspension med 200 g/l, et præparat indeholdende tebuconazol i form af et emulgerbart koncentrat med 250 g/l eller også et præparat ifølge opfindelsen opnået ved blanding af de to foregående præparater.Either a composition containing bromuconazole is used in the form of a concentrated suspension of 200 g / L, a preparation containing tebuconazole in the form of an emulsifiable concentrate of 250 g / L or also a composition of the invention obtained by mixing the previous two compositions.
Når der er tale om en blanding af aktive stoffer, er vægtforholdet mellem bromuconazol og tebuconazol 1, 1,5, 2, 2,5 og 3.In the case of a mixture of active substances, the weight ratio of bromuconazole to tebuconazole is 1, 1.5, 2, 2.5 and 3.
10 Hvedeplanter (varietet Talent) dyrkes i potter. Når planterne har en alder på 14 dage, hvilket svarer til Zadocks-stadiet 11, behandles de ved forstøvning af hvert af de ovenfor anførte præparater.10 Wheat plants (variety Talent) are grown in pots. When the plants have an age of 14 days, which corresponds to Zadocks stage 11, they are treated by spraying each of the preparations listed above.
Skalaen ifølge Zadoks er defineret i en artikel i Phytiatrie phytopharmacie 1977, 26, side 129-140, med titlen “Un code decimal pour les stades de croissance 15 des céréales”, af J.C. Zadoks, T.T. Chang, C.F. Konzak.The scale according to Zadoks is defined in an article in Phytiatrie phytopharmacie 1977, 26, pages 129-140, entitled “Un code decimal for les stades de croissance 15 des céréales”, by J.C. Zadoks, T.T. Chang, C.F. Konzak.
24 timer efter behandlingen podes hver plante ved forstøvning af en vandig sporesuspension (100.000 sporer/cm3) af Puccinia recondita.Twenty-four hours after treatment, each plant is seeded by spraying an aqueous spore suspension (100,000 spores / cm3) of Puccinia recondita.
Efter denne podning inkuberes hvedeplanteme ved 20°C og 100% relativ fugtighed i 24 timer, hvorefter de anbringes under glas ved 18°C og 70% relativ fugtighed.After this grafting, the wheat plants are incubated at 20 ° C and 100% relative humidity for 24 hours, then placed under glass at 18 ° C and 70% relative humidity.
20 12 dage efter podningen foretages en bestemmelse af den procentiske kon- taminerede bladoverflade. Ved sammenligning med en kontrol-hvedeplante, som ikke er behandlet med et aktivt stof, men er blevet podet med Puccinia recondita, beregnes den procentiske ødelæggelse af den fytopatogene svamp.Twenty-12 days after inoculation, the percentage of contaminated leaf surface is determined. When compared to a control wheat plant, which has not been treated with an active substance but has been seeded with Puccinia recondita, the percent destruction of the phytopathogenic fungus is calculated.
De opnåede resultater er angivet i form af punkter, svarende til 80%’s øde-25 læggelse af mikroorganismen og placeret i et Tammes-diagram, hvori der ad abscissen er anført doserne af tebuconazol udtrykt i g/ha og ad ordinaten er anført doserne af bromuconazol, ligeledes i g/ha.The results obtained are in the form of points corresponding to 80% destruction of the microorganism and placed in a Tammes diagram, in which the doses of tebuconazole expressed in g / ha and the doses of bromuconazole, also in g / ha.
Der fås diagrammet i fig. 1, hvoraf det fremgår, at tilsætning af en dosis af tebuconazol på under 28 g/ha (som svarer til den dosis af tebuconazol alene, som det 30 er nødvendigt at anvende for at opnå en 80%’s ødelæggelse af mikroorganismen) ganske uventet gør det muligt at nedsætte den dosis af bromuconazol, som er nødvendig til 80%’s ødelæggelse af mikroorganismen, til godt under 337 g/ha (denne værdi svarer til den dosis af bromuconazoi alene, som det er nødvendigt at anvende for at opnå den samme 80%'s ødelæggelse).The diagram of FIG. 1, which shows that the addition of a dose of tebuconazole below 28 g / ha (which corresponds to the dose of tebuconazole alone which is necessary to use to achieve an 80% destruction of the microorganism) is quite unexpected allows the dose of bromuconazole required for 80% destruction of the microorganism to be reduced to well below 337 g / ha (this value corresponds to the dose of bromuconazole alone needed to obtain it same 80% destruction).
7 DK 176435 B17 DK 176435 B1
Den opnåede placering af punkterne viser således en tosidet virkning, som på engelsk ifølge den ovennævnte Tammes-metode betegnes “two sided effect”. Denne placering svarer til en isobol af type III ifølge den nævnte metode (side 75 i den allerede anførte litteraturreference) og er karakteristisk for en synergi.Thus, the obtained position of the points shows a two-sided effect, which in English according to the above-mentioned Tammes method is called “two sided effect”. This location corresponds to a type III isobol according to the method mentioned (page 75 of the literature reference already cited) and is characteristic of a synergy.
55
Eksempel 2: Forsøg under glas med et præparat indeholdende en blanding af bromuconazol og epoxiconazol på Septoria tritici, som er ansvarlig for septoriose i hvede.Example 2: Glass test with a composition containing a mixture of bromuconazole and epoxiconazole on Septoria tritici, which is responsible for septoriosis in wheat.
Der anvendes enten et præparat indeholdende bromuconazol i form af en 10 koncentreret suspension med 200 g/l, et præparat indeholdende epoxiconazol i form af en koncentreret suspension med 125 g/l eller også et præparat ifølge opfindelsen opnået ved blanding af de to foregående præparater.Either a composition containing bromuconazole in the form of a concentrated concentration of 200 g / l, a composition containing epoxiconazole in the form of a concentrated suspension of 125 g / l or also a composition of the invention obtained by mixing the preceding two compositions is used.
Når der er tale om en blanding af aktive stoffer, er vægtforholdet mellem bromuconazol og epoxiconazol 1, 3, 4, 5 og 6.In the case of a mixture of active substances, the weight ratio of bromuconazole to epoxiconazole is 1, 3, 4, 5 and 6.
15 Hvedeplanter (varietet Darius) dyrkes i potter. Når planterne har en alder på 14 dage, hvilket svarer til Zadocks-stadiet 11, behandles de ved forstøvning af hvert af de ovenfor anførte præparater.15 Wheat plants (variety Darius) are grown in pots. When the plants have an age of 14 days, which corresponds to Zadocks stage 11, they are treated by spraying each of the preparations listed above.
24 timer efter behandling podes hver plante ved forstøvning af en vandig sporesuspension (250.000 sporer/cm3) af Septoria tritici.Twenty-four hours after treatment, each plant is seeded by spraying an aqueous spore suspension (250,000 spores / cm3) of Septoria tritici.
20 Efter denne podning inkuberes hvedeplanterne ved 18°C og 100% relativ fug tighed i 4 dage, hvorefter de anbringes under glas ved 18°C og 90% relativ fugtighed.After this grafting, the wheat plants are incubated at 18 ° C and 100% relative humidity for 4 days, then placed under glass at 18 ° C and 90% relative humidity.
20 dage efter podningen foretages en bestemmelse af den procentiske kon-taminerede bladoverflade. Ved sammenligning med en kontrol-hvedeplante, som ikke er behandlet med et aktivt stof, men er blevet podet med Septoria tritici, beregnes den 25 procentiske udryddelse af den fytopatogene svamp.Twenty days after grafting, the percentage of contaminated leaf surface is determined. When compared to a control wheat plant, which has not been treated with an active substance but has been seeded with Septoria tritici, the 25% eradication of the phytopathogenic fungus is calculated.
De opnåede resultater er angivet i form af punkter, svarende til 50% udryddelse af mikroorganismen og placeret i et Tammes-diagram, hvori der ad abscissen er anført doserne af epoxiconazol udtrykt i g/ha og ad ordinaten doserne af bromuconazol, ligeledes i g/ha.The results obtained are expressed in points corresponding to 50% eradication of the microorganism and placed in a Tammes diagram, indicating the doses of epoxiconazole expressed in g / ha and the doses of bromuconazole, also in g / ha.
30 Der fås diagrammet i fig. 2, hvoraf det fremgår, at tilsætning af en dosis af epoxiconazol på under 7 g/ha (hvilket svarer til den dosis af epoxiconazol alene, som det er nødvendigt at anvende for at opnå en 50%’s udryddelse af mikroorganismen) ganske uventet gør det muligt at nedsætte dosen af bromuconazol, som er nødvendig for 50%’s udryddelse af mikroorganismen, til godt under 101 g/ha (denne værdi svarer DK 176435 B1 8 til den dosis af bromuconazot alene, som det er nødvendigt at anvende for at opnå den samme procentiske udryddelse på 50%).30 The diagram of FIG. 2, which shows that the addition of a dose of epoxiconazole below 7 g / ha (which corresponds to the dose of epoxiconazole alone needed to achieve a 50% eradication of the microorganism) quite unexpectedly does it is possible to reduce the dose of bromuconazole required for 50% eradication of the microorganism to well below 101 g / ha (this value corresponds to the dose of bromuconazole alone which it is necessary to use to achieve the same percentage extinction of 50%).
Placeringen af de opnåede punkter, især placeringen svarende til forholdene 3, 4, 5 og 6, viser en tosidet virkning, som er karakteristisk for en synergi.The location of the points obtained, especially the position corresponding to conditions 3, 4, 5 and 6, shows a two-sided effect characteristic of a synergy.
Claims (9)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9609138A FR2751173B1 (en) | 1996-07-16 | 1996-07-16 | FUNGICIDE COMPOSITION BASED ON 2 TRIAZOLE-LIKE COMPOUNDS |
| FR9609138 | 1996-07-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK86997A DK86997A (en) | 1998-01-17 |
| DK176435B1 true DK176435B1 (en) | 2008-02-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK199700869A DK176435B1 (en) | 1996-07-16 | 1997-07-15 | Fungicide preparation based on two compounds of the triazole type and method of combating or preventing fungal infestation on culture plants |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE1010505A3 (en) |
| CZ (1) | CZ293674B6 (en) |
| DE (1) | DE19730134B4 (en) |
| DK (1) | DK176435B1 (en) |
| FR (1) | FR2751173B1 (en) |
| GB (1) | GB2315218B (en) |
| HU (1) | HU227789B1 (en) |
| NL (1) | NL1006531C2 (en) |
| PL (1) | PL187142B1 (en) |
| RO (1) | RO116858B1 (en) |
| RU (1) | RU2165701C2 (en) |
| SK (1) | SK284515B6 (en) |
| UA (1) | UA58490C2 (en) |
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| WO2007028753A2 (en) * | 2005-09-09 | 2007-03-15 | Basf Aktiengesellschaft | Triazole-based fungicidal mixtures |
| AU2006289118A1 (en) * | 2005-09-09 | 2007-03-15 | Basf Se | Triazole-based fungicidal mixtures |
| WO2007028756A1 (en) * | 2005-09-09 | 2007-03-15 | Basf Se | Triazole-based fungicidal mixtures |
| BRPI0615840A2 (en) * | 2005-09-14 | 2012-12-18 | Basf Se | fungicidal mixture, process to combat harmful fungi, seed, use of compost, and fungicidal agent |
| JP5365158B2 (en) | 2008-11-25 | 2013-12-11 | 住友化学株式会社 | Composition for controlling plant diseases and method for controlling plant diseases |
| CN102754649B (en) * | 2012-08-01 | 2013-08-21 | 杭州宇龙化工有限公司 | Sterilizing composition containing phenylate bi (imidazole) and epoxiconazole |
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| GB8908794D0 (en) * | 1989-04-19 | 1989-06-07 | Janssen Pharmaceutica Nv | Synergistic compositions containing propiconazole and tebuconazole |
| DE4139637A1 (en) * | 1991-12-02 | 1993-06-03 | Bayer Ag | FUNGICIDAL ACTIVE COMPOUNDS |
| GB9204878D0 (en) * | 1992-03-05 | 1992-04-22 | Sandoz Ltd | Fungicidal compositions |
| DE4318285A1 (en) * | 1993-06-02 | 1994-12-08 | Bayer Ag | Fungicidal active ingredient combinations |
| DE4406819A1 (en) * | 1994-03-02 | 1995-09-07 | Bayer Ag | Wood preservative, esp. for fungus and insect control |
| TW286264B (en) * | 1994-05-20 | 1996-09-21 | Ciba Geigy Ag | |
| US5714507A (en) * | 1994-07-01 | 1998-02-03 | Janssen Pharmaceutica, N.V. | Synergistic compositions containing metconazole and another triazole |
| DE4437048A1 (en) * | 1994-10-17 | 1996-04-18 | Bayer Ag | Fungicidal active ingredient combinations |
-
1996
- 1996-07-16 FR FR9609138A patent/FR2751173B1/en not_active Expired - Lifetime
-
1997
- 1997-07-02 BE BE9700568A patent/BE1010505A3/en active
- 1997-07-09 RO RO97-01276A patent/RO116858B1/en unknown
- 1997-07-10 NL NL1006531A patent/NL1006531C2/en not_active IP Right Cessation
- 1997-07-14 PL PL97321120A patent/PL187142B1/en unknown
- 1997-07-14 DE DE19730134A patent/DE19730134B4/en not_active Expired - Lifetime
- 1997-07-14 SK SK956-97A patent/SK284515B6/en not_active IP Right Cessation
- 1997-07-14 CZ CZ19972227A patent/CZ293674B6/en not_active IP Right Cessation
- 1997-07-15 DK DK199700869A patent/DK176435B1/en not_active IP Right Cessation
- 1997-07-15 HU HU9701205A patent/HU227789B1/en unknown
- 1997-07-15 RU RU97112691/04A patent/RU2165701C2/en active
- 1997-07-15 UA UA97073775A patent/UA58490C2/en unknown
- 1997-07-16 GB GB9714972A patent/GB2315218B/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK86997A (en) | 1998-01-17 |
| HUP9701205A3 (en) | 2000-05-29 |
| RU2165701C2 (en) | 2001-04-27 |
| GB2315218B (en) | 2000-08-09 |
| GB2315218A (en) | 1998-01-28 |
| HU227789B1 (en) | 2012-03-28 |
| RO116858B1 (en) | 2001-07-30 |
| SK284515B6 (en) | 2005-05-05 |
| CZ222797A3 (en) | 1998-02-18 |
| CZ293674B6 (en) | 2004-06-16 |
| DE19730134A1 (en) | 1998-01-22 |
| PL321120A1 (en) | 1998-01-19 |
| UA58490C2 (en) | 2003-08-15 |
| DE19730134B4 (en) | 2009-08-20 |
| BE1010505A3 (en) | 1998-10-06 |
| SK95697A3 (en) | 1998-02-04 |
| NL1006531C2 (en) | 1998-01-21 |
| FR2751173B1 (en) | 1998-08-28 |
| HU9701205D0 (en) | 1997-08-28 |
| PL187142B1 (en) | 2004-05-31 |
| HUP9701205A2 (en) | 1998-03-30 |
| GB9714972D0 (en) | 1997-09-24 |
| FR2751173A1 (en) | 1998-01-23 |
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