DK1758569T3 - Guanylhydrazonsalte, sammensætninger, fremgangsmåder til fremstilling og fremgangsmåder til anvendelse - Google Patents

Guanylhydrazonsalte, sammensætninger, fremgangsmåder til fremstilling og fremgangsmåder til anvendelse

Info

Publication number
DK1758569T3
DK1758569T3 DK05763891.8T DK05763891T DK1758569T3 DK 1758569 T3 DK1758569 T3 DK 1758569T3 DK 05763891 T DK05763891 T DK 05763891T DK 1758569 T3 DK1758569 T3 DK 1758569T3
Authority
DK
Denmark
Prior art keywords
methods
compositions
preparation
guanyl hydrazone
hydrazone salts
Prior art date
Application number
DK05763891.8T
Other languages
English (en)
Inventor
Thais M Sielecki-Dzurdz
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Application granted granted Critical
Publication of DK1758569T3 publication Critical patent/DK1758569T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DK05763891.8T 2004-06-25 2005-06-27 Guanylhydrazonsalte, sammensætninger, fremgangsmåder til fremstilling og fremgangsmåder til anvendelse DK1758569T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58253204P 2004-06-25 2004-06-25
US60199204P 2004-08-17 2004-08-17
US11/165,255 US7244765B2 (en) 2004-06-25 2005-06-24 Guanylhydrazone salts, compositions, processes of making and methods of using
PCT/US2005/022626 WO2006004613A2 (en) 2004-06-25 2005-06-27 Guanylhydrazone salts, compositions, processes of making and methods of using

Publications (1)

Publication Number Publication Date
DK1758569T3 true DK1758569T3 (da) 2013-07-01

Family

ID=35600290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05763891.8T DK1758569T3 (da) 2004-06-25 2005-06-27 Guanylhydrazonsalte, sammensætninger, fremgangsmåder til fremstilling og fremgangsmåder til anvendelse

Country Status (12)

Country Link
US (3) US7244765B2 (da)
EP (2) EP2540703B1 (da)
JP (2) JP5086072B2 (da)
CN (1) CN1968686B (da)
AU (1) AU2005260126B2 (da)
BR (1) BRPI0511819A (da)
CA (1) CA2566648C (da)
DK (1) DK1758569T3 (da)
ES (1) ES2424356T3 (da)
PL (1) PL1758569T3 (da)
PT (1) PT1758569E (da)
WO (1) WO2006004613A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244765B2 (en) * 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
CN102936212A (zh) * 2004-08-17 2013-02-20 辉凌公司 脒腙化合物、组合物、制备方法及使用方法
CA2655632A1 (en) * 2006-06-23 2008-01-03 The Feinstein Institute For Medical Research Inhibitors of a.beta. and synuclein aggregation
WO2009054994A2 (en) * 2007-10-23 2009-04-30 President And Fellows Of Harvard College Sirt-3 related methods and compositions for mimicking exercise
MX2011003002A (es) * 2008-09-19 2011-05-31 Cytokine Pharmasciences Inc Prevención de poi.

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US4321253A (en) 1980-08-22 1982-03-23 Beatty Morgan L Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
DK161312C (da) 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
DK147640C (da) 1982-06-11 1985-05-06 Dumex Ltd As Fremgangsmaade til fremstilling af nitroimidazol-derivater
US5272165A (en) 1984-03-19 1993-12-21 The Rockefeller University 2-alkylidene-aminoguanidines and methods of use therefor
US4791196A (en) 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt
US5690954A (en) 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
US5028625A (en) 1989-06-20 1991-07-02 American Home Products Corporation Acid addition salt of ibuprofen and meglumine
US7425543B2 (en) 1992-11-16 2008-09-16 The Corporation Of Mercer University Microencapsulated materials and method of making same
US5599984A (en) 1994-01-21 1997-02-04 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US6008255A (en) 1994-01-21 1999-12-28 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US5567592A (en) 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5599986A (en) * 1994-09-29 1997-02-04 Hoechst Marion Roussel Inc. Process for the preparation of alkali metal salts of diformylamide
US5993858A (en) 1996-06-14 1999-11-30 Port Systems L.L.C. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
CN1230123A (zh) 1996-07-11 1999-09-29 荷兰发马克有限公司 含碱性药物的酸加成盐的药物组合物
DE69739734D1 (de) 1996-11-15 2010-02-25 Cytokine Pharmasciences Inc Guanylhydrazone die nützlich sind zur behandlung von mit t-zellen verbundenen krankheiten
US6319894B1 (en) * 1997-01-08 2001-11-20 The Picower Institute For Medical Research Complexes and combinations of fetuin with therapeutic agents
FR2758459B1 (fr) 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
FR2760190B1 (fr) 1997-02-28 1999-04-09 Adir Composition pharmaceutique pour la liberation programmee de dexfenfluramine
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CA2643231A1 (en) 1999-07-01 2001-01-11 Pharmacia & Upjohn Company Norepinephrine reuptake inhibitors and methods of using the same
DE60114772T2 (de) 2000-02-02 2006-07-20 Dorian Bevec Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen
AU2001269092A1 (en) * 2000-06-27 2002-01-08 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
CA2775616C (en) 2000-08-04 2013-09-17 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and application thereof
WO2002058699A1 (en) 2001-01-25 2002-08-01 Bristol-Myers Squibb Company Pharmaceutical forms of epothilones for oral administration
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US20030198669A1 (en) 2001-07-05 2003-10-23 R.T. Alamo Ventures I, Llc Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
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MXPA04005210A (es) 2001-11-29 2004-08-19 Schering Corp Procedimiento para la preparacion de composiciones que tienen una cantidad incrementada de sales farmaceuticamente activas de rotameros.
CN100436449C (zh) 2001-11-29 2008-11-26 先灵公司 作为ccr5-拮抗剂用于治疗aids和相关的hiv感染的药用盐的制备
CA2476896A1 (en) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
GB0207104D0 (en) 2002-03-26 2002-05-08 Pfizer Ltd Stable hydrate of a muscarinic receptor antagonist
EP1389480A1 (en) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Therapeutical use of guanylhydrazones for the inhibition of CD83 dependent processes and dendritic cell maturation
US7244765B2 (en) 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
US7795314B2 (en) * 2005-06-01 2010-09-14 Cytokine Pharmasciences, Inc. Protective role of semapimod in necrotizing enterocolitis

Also Published As

Publication number Publication date
PT1758569E (pt) 2013-08-23
JP2012121905A (ja) 2012-06-28
WO2006004613A2 (en) 2006-01-12
JP5576416B2 (ja) 2014-08-20
EP2540703A1 (en) 2013-01-02
PL1758569T3 (pl) 2013-10-31
US20080262090A1 (en) 2008-10-23
AU2005260126A1 (en) 2006-01-12
US20060014833A1 (en) 2006-01-19
US8497306B2 (en) 2013-07-30
EP1758569A2 (en) 2007-03-07
CN1968686A (zh) 2007-05-23
US20080146670A1 (en) 2008-06-19
AU2005260126B2 (en) 2012-04-19
EP1758569B1 (en) 2013-05-08
US7244765B2 (en) 2007-07-17
JP5086072B2 (ja) 2012-11-28
BRPI0511819A (pt) 2007-12-26
CN1968686B (zh) 2013-01-16
ES2424356T3 (es) 2013-10-01
US8034840B2 (en) 2011-10-11
EP2540703B1 (en) 2015-05-27
CA2566648C (en) 2013-04-02
CA2566648A1 (en) 2006-01-12
EP1758569A4 (en) 2010-01-20
JP2008504288A (ja) 2008-02-14
WO2006004613A3 (en) 2006-05-26

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