DK175390A - Paramagnetiske forbindelser - Google Patents

Paramagnetiske forbindelser Download PDF

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Publication number
DK175390A
DK175390A DK175390A DK175390A DK175390A DK 175390 A DK175390 A DK 175390A DK 175390 A DK175390 A DK 175390A DK 175390 A DK175390 A DK 175390A DK 175390 A DK175390 A DK 175390A
Authority
DK
Denmark
Prior art keywords
paramagnetic
connections
paramagnetic connections
Prior art date
Application number
DK175390A
Other languages
Danish (da)
English (en)
Other versions
DK175390D0 (da
Inventor
Jo Klaveness
P L Rongved
Per Strande
Original Assignee
Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed As filed Critical Nycomed As
Publication of DK175390D0 publication Critical patent/DK175390D0/da
Publication of DK175390A publication Critical patent/DK175390A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK175390A 1988-01-26 1990-07-23 Paramagnetiske forbindelser DK175390A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888801646A GB8801646D0 (en) 1988-01-26 1988-01-26 Chemical compounds
PCT/EP1989/000078 WO1989006979A1 (en) 1988-01-26 1989-01-26 Paramagnetic compounds

Publications (2)

Publication Number Publication Date
DK175390D0 DK175390D0 (da) 1990-07-23
DK175390A true DK175390A (da) 1990-09-20

Family

ID=10630512

Family Applications (1)

Application Number Title Priority Date Filing Date
DK175390A DK175390A (da) 1988-01-26 1990-07-23 Paramagnetiske forbindelser

Country Status (13)

Country Link
US (1) US5208324A (de)
EP (2) EP0396617B1 (de)
JP (1) JPH03502338A (de)
CA (1) CA1331458C (de)
DK (1) DK175390A (de)
FI (1) FI903108A0 (de)
GB (1) GB8801646D0 (de)
HU (1) HU205212B (de)
IE (1) IE890233L (de)
NZ (1) NZ227750A (de)
RU (1) RU2081881C1 (de)
WO (1) WO1989006979A1 (de)
ZA (1) ZA89628B (de)

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US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
GB8900719D0 (en) * 1989-01-13 1989-03-08 Nycomed As Compounds
US5395608A (en) * 1989-04-26 1995-03-07 The Curators Of The University Of Missouri Triamine chelants, their derivatives, complexes and conjugates
AU625529B2 (en) * 1989-12-22 1992-07-16 E.R. Squibb & Sons, Inc. 10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes
AU6709390A (en) * 1989-12-22 1991-06-27 E.R. Squibb & Sons, Inc. 10-(2'-hydroxy-3'-polyoxaalkyl)-1,4,7-tris-carboxymethyl -1,4,7,10-tetraazacyclododecane
EP0511275A1 (de) * 1990-01-19 1992-11-04 Nycomed Imaging As Komplexbildner
US5236694A (en) * 1990-02-21 1993-08-17 The Board Of Regents, The University Of Texas System 19f labelled dextrans and antibodies as nmr imaging and spectroscopy agents
US5190744A (en) * 1990-03-09 1993-03-02 Salutar Methods for detecting blood perfusion variations by magnetic resonance imaging
US5494655A (en) * 1990-03-09 1996-02-27 The Regents Of The University Of California Methods for detecting blood perfusion variations by magnetic resonance imaging
FR2663544B1 (fr) * 1990-06-26 1994-05-06 Medgenix Group Sa Agent de contraste pour l'imagerie par rmn et agents chelateurs comportant des structures peptidiques.
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
CA2115275A1 (en) * 1991-08-09 1993-02-18 David L. White Amino acid, ester and/or catechol contrast agents for mri
AU663572B2 (en) * 1992-03-27 1995-10-12 Nihon Medi-Physics Co., Ltd. Tetraazacyclododecane derivative and its use
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5871710A (en) * 1992-09-04 1999-02-16 The General Hospital Corporation Graft co-polymer adducts of platinum (II) compounds
EP0665729B1 (de) * 1992-09-04 2003-05-07 The General Hospital Corporation Diagnostische und therapeutische Einheiten enthaltende biokompatible Polymere
US5817292A (en) * 1992-10-14 1998-10-06 Nycomed Imaging As MR imaging compositions and methods
US5756688A (en) * 1992-10-14 1998-05-26 Sterling Winthrop Inc. MR imaging compositions and methods
US5401493A (en) * 1993-03-26 1995-03-28 Molecular Biosystems, Inc. Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same
CA2163232A1 (en) * 1993-05-20 1994-12-08 Robert C. Brasch Macromolecular contrast media for mr imaging
US5605672A (en) * 1993-06-09 1997-02-25 The General Hospital Corporation Blood pool imaging composition and method of its use
AU698176B2 (en) * 1993-07-28 1998-10-29 Cis Bio International Radiolabelled glucans
US5730968A (en) * 1994-03-31 1998-03-24 Sterling Winthrop Inc. Segmented chelating polymers as imaging and therapeutic agents
CA2160819A1 (en) * 1994-10-21 1996-04-22 Yuji Hashiguchi Diagnostic imaging agent
US5602180A (en) * 1995-03-31 1997-02-11 World Health Group Method of administering EDTA complexes
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
US6107090A (en) 1996-05-06 2000-08-22 Cornell Research Foundation, Inc. Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
NL1003776C2 (nl) * 1996-08-09 1998-02-20 Cooperatie Cosun U A Milieuvriendelijke complexanten voor zware metalen
US6045776A (en) * 1996-12-04 2000-04-04 Schering Aktiengesellschaft Process for the production of metal-complex carboxylic acid amides
DE19808079A1 (de) * 1998-02-20 1999-08-26 Schering Ag Hydroxyethylstärke-Konjugate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
WO2002096460A1 (en) * 2001-05-30 2002-12-05 Cornell Research Foundation, Inc. Endopeptidase/anti-psma antibody fusion proteins for treatment of cancer
US7666414B2 (en) * 2001-06-01 2010-02-23 Cornell Research Foundation, Inc. Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
US7514078B2 (en) * 2001-06-01 2009-04-07 Cornell Research Foundation, Inc. Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
IL158969A0 (en) 2001-06-01 2004-05-12 Cornell Res Foundation Inc Modified antibodies to prostate-specific membrane antigen and uses thereof
AU2002305767B2 (en) * 2001-09-20 2008-04-10 Cornell Research Foundation, Inc. Methods and compositions for treating and preventing skin disorders using binding agents specific for PSMA
US20040136998A1 (en) * 2002-10-30 2004-07-15 Bander Neil H. Methods and compositions for treating or preventing insulin-related disorders using binding agents specific for prostate specific membrane antigen
AU2003293556A1 (en) 2003-01-10 2004-08-10 Millennium Pharmaceuticals, Inc. Methods of diagnosing and treating cancer
WO2005070456A2 (en) * 2004-01-09 2005-08-04 Millennium Pharmaceuticals, Inc. Diagnosing and treating female reproductive tract or chilhood cancer with pmsa antibodies
WO2005094882A1 (en) * 2004-03-03 2005-10-13 Millennium Pharmaceuticals, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
WO2006124726A2 (en) 2005-05-12 2006-11-23 The General Hospital Corporation Novel biotinylated compositions
US8323676B2 (en) * 2008-06-30 2012-12-04 Abbott Cardiovascular Systems Inc. Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
US20090258028A1 (en) * 2006-06-05 2009-10-15 Abbott Cardiovascular Systems Inc. Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug
DE102007002726A1 (de) 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US8765162B2 (en) 2008-06-30 2014-07-01 Abbott Cardiovascular Systems Inc. Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
US20100196272A1 (en) * 2009-01-30 2010-08-05 Neoprobe Corporation Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran
JP6209159B2 (ja) * 2011-06-21 2017-10-04 イミュノジェン・インコーポレーテッド ペプチドリンカーを有する新規メイタンシノイド誘導体およびその結合体
CA2883130A1 (en) 2012-08-31 2014-03-06 The General Hospital Corporation Biotin complexes for treatment and diagnosis of alzheimer's disease
WO2018053460A1 (en) * 2016-09-19 2018-03-22 The Regents Of The University Of California Paramagnetic polymers
EP3551231A4 (de) 2016-12-08 2020-08-12 The Brigham and Women's Hospital, Inc. Bismut-gadolinium nanopartikel
WO2021189052A1 (en) 2020-03-20 2021-09-23 Robert Taub Composition for radiation treatment of intracavitary or metastatic deposits of malignancy and method for treatment therewith
FR3116197A1 (fr) * 2020-11-19 2022-05-20 Nh Theraguix Procédé de traitement de tumeurs par captation du cuivre et/ou du fer

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SE420565B (sv) * 1974-06-06 1981-10-19 Pharmacia Ab Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4741900A (en) * 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
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DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
CA1243602A (en) * 1983-08-25 1988-10-25 Hong-Ning Yeung Methods for enhancing the contrast in nmr imaging
US4615879A (en) * 1983-11-14 1986-10-07 Vanderbilt University Particulate NMR contrast agents for gastrointestinal application
GB8413772D0 (en) * 1984-05-30 1984-07-04 Nyegaard & Co As Chemical compounds
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US4687658A (en) * 1984-10-04 1987-08-18 Salutar, Inc. Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging
US4687659A (en) * 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US4639365A (en) * 1984-10-18 1987-01-27 The Board Of Regents, The University Of Texas System Gadolinium chelates as NMR contrast agents
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Also Published As

Publication number Publication date
ZA89628B (en) 1989-10-25
US5208324A (en) 1993-05-04
HU205212B (en) 1992-03-30
EP0396617B1 (de) 1992-06-24
CA1331458C (en) 1994-08-16
HU891057D0 (en) 1990-12-28
IE890233L (en) 1989-07-26
RU2081881C1 (ru) 1997-06-20
JPH03502338A (ja) 1991-05-30
GB8801646D0 (en) 1988-02-24
DK175390D0 (da) 1990-07-23
FI903108A0 (fi) 1990-06-20
NZ227750A (en) 1991-03-26
WO1989006979A1 (en) 1989-08-10
EP0326226A1 (de) 1989-08-02
EP0396617A1 (de) 1990-11-14
HUT55022A (en) 1991-04-29

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment