DK174888B1 - Fremgangsmåde til fremstilling af tertiære karbinoler indeholdende en aminisk substituent - Google Patents

Fremgangsmåde til fremstilling af tertiære karbinoler indeholdende en aminisk substituent Download PDF

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Publication number
DK174888B1
DK174888B1 DK198900912A DK91289A DK174888B1 DK 174888 B1 DK174888 B1 DK 174888B1 DK 198900912 A DK198900912 A DK 198900912A DK 91289 A DK91289 A DK 91289A DK 174888 B1 DK174888 B1 DK 174888B1
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DK
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Prior art keywords
acid
mixture
reaction mixture
temperature
formula
Prior art date
Application number
DK198900912A
Other languages
Danish (da)
English (en)
Other versions
DK91289D0 (da
DK91289A (da
Inventor
Elvio Bellasio
Original Assignee
Aventis Bulk S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Bulk S P A filed Critical Aventis Bulk S P A
Publication of DK91289D0 publication Critical patent/DK91289D0/da
Publication of DK91289A publication Critical patent/DK91289A/da
Application granted granted Critical
Publication of DK174888B1 publication Critical patent/DK174888B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/22—Trihydroxylic alcohols, e.g. glycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198900912A 1988-03-03 1989-02-27 Fremgangsmåde til fremstilling af tertiære karbinoler indeholdende en aminisk substituent DK174888B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8805113 1988-03-03
GB888805113A GB8805113D0 (en) 1988-03-03 1988-03-03 Process for preparation of tertiary carbinols containing aminic substituent

Publications (3)

Publication Number Publication Date
DK91289D0 DK91289D0 (da) 1989-02-27
DK91289A DK91289A (da) 1989-09-04
DK174888B1 true DK174888B1 (da) 2004-01-19

Family

ID=10632804

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900912A DK174888B1 (da) 1988-03-03 1989-02-27 Fremgangsmåde til fremstilling af tertiære karbinoler indeholdende en aminisk substituent

Country Status (15)

Country Link
US (1) US5777125A (fr)
EP (1) EP0330875B1 (fr)
JP (1) JPH023615A (fr)
KR (1) KR960009681B1 (fr)
AT (1) ATE126507T1 (fr)
CA (1) CA1340055C (fr)
DE (1) DE68923808T2 (fr)
DK (1) DK174888B1 (fr)
ES (1) ES2075000T3 (fr)
GB (1) GB8805113D0 (fr)
GR (1) GR3017284T3 (fr)
HU (1) HU209295B (fr)
IE (1) IE67632B1 (fr)
IL (1) IL89403A0 (fr)
ZA (1) ZA891134B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3856850B2 (ja) * 1994-08-18 2006-12-13 生化学工業株式会社 光学活性アミノケトン及びアミノアルコールの製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3000896A (en) * 1961-09-19 Process for the manufacture of second-
US2624739A (en) * 1949-11-23 1953-01-06 Wm S Merrell Co Alpha, alpha diaryl piperidino methanols
US2833775A (en) * 1951-08-17 1958-05-06 Schering Corp Substituted piperidines
US2804422A (en) * 1954-12-29 1957-08-27 Wm S Merrell Co Tranquilizing composition comprising alpha phenyl, alpha-(4-piperidyl)-benzyl alcohol and method of using same
GB805511A (en) * 1956-01-25 1958-12-10 Mead Johnson & Co 1,1-diaryl-2-aminoalkanols
US2879294A (en) * 1956-01-25 1959-03-24 Mead Johnson & Co 1, 1-diaryl-2-aminoalkanols
US2832786A (en) * 1956-02-27 1958-04-29 Wm S Merrell Co Phosphoramides
US3052685A (en) * 1961-12-05 1962-09-04 Abbott Lab Diphenyl 4-piperidyl carbinol andits acid-addition salts
JPS6016928B2 (ja) * 1979-10-31 1985-04-30 住友化学工業株式会社 光学活性アミノアルコ−ルの製法

Also Published As

Publication number Publication date
IE67632B1 (en) 1996-04-17
EP0330875A2 (fr) 1989-09-06
GB8805113D0 (en) 1988-03-30
ES2075000T3 (es) 1995-10-01
DE68923808T2 (de) 1995-12-21
US5777125A (en) 1998-07-07
HUT54618A (en) 1991-03-28
KR890014420A (ko) 1989-10-23
GR3017284T3 (en) 1995-11-30
IE890376L (en) 1989-09-03
IL89403A0 (en) 1989-09-10
DE68923808D1 (de) 1995-09-21
ZA891134B (en) 1990-03-28
HU209295B (en) 1994-04-28
KR960009681B1 (en) 1996-07-23
EP0330875A3 (en) 1990-10-10
EP0330875B1 (fr) 1995-08-16
DK91289D0 (da) 1989-02-27
DK91289A (da) 1989-09-04
ATE126507T1 (de) 1995-09-15
JPH023615A (ja) 1990-01-09
CA1340055C (fr) 1998-09-22

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