DK172481A - Fremgangsmaade til fremstilling af dipeptidyl-4-0-og-6-0-acyl-2-amino-2-deoxy-d-glucosederivater - Google Patents

Fremgangsmaade til fremstilling af dipeptidyl-4-0-og-6-0-acyl-2-amino-2-deoxy-d-glucosederivater

Info

Publication number
DK172481A
DK172481A DK172481A DK172481A DK172481A DK 172481 A DK172481 A DK 172481A DK 172481 A DK172481 A DK 172481A DK 172481 A DK172481 A DK 172481A DK 172481 A DK172481 A DK 172481A
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
phenyl
substituted
amino
Prior art date
Application number
DK172481A
Other languages
English (en)
Inventor
T Y Shen
P L Durette
C P Dorn
J B Doherty
R T Dean
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK172481A publication Critical patent/DK172481A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK172481A 1980-04-17 1981-04-15 Fremgangsmaade til fremstilling af dipeptidyl-4-0-og-6-0-acyl-2-amino-2-deoxy-d-glucosederivater DK172481A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/141,227 US4368190A (en) 1980-04-17 1980-04-17 Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation

Publications (1)

Publication Number Publication Date
DK172481A true DK172481A (da) 1981-10-18

Family

ID=22494746

Family Applications (1)

Application Number Title Priority Date Filing Date
DK172481A DK172481A (da) 1980-04-17 1981-04-15 Fremgangsmaade til fremstilling af dipeptidyl-4-0-og-6-0-acyl-2-amino-2-deoxy-d-glucosederivater

Country Status (10)

Country Link
US (1) US4368190A (da)
EP (1) EP0038750B1 (da)
JP (1) JPS56164196A (da)
AT (1) ATE23537T1 (da)
CA (1) CA1174232A (da)
DE (1) DE3175602D1 (da)
DK (1) DK172481A (da)
ES (1) ES501457A0 (da)
GR (1) GR76828B (da)
PT (1) PT72866B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA853989B (en) * 1984-05-29 1986-01-29 Ciba Geigy Ag Acylated sugar derivatives,processes for their manufacture,and their use
US4640911A (en) * 1985-05-29 1987-02-03 Ciba-Geigy Corporation Acylated sugar derivatives, processes for their manufacture, and their use
US4937077A (en) * 1987-09-21 1990-06-26 Eastman Kodak Company Method for improving feed conversion of meat-producing animals by oral administration of 2-deoxy-D-hexose
US4866035A (en) * 1987-10-05 1989-09-12 Merck & Co., Inc. Dipeptidyl saccharides as host resistance enhancers in AIDS-immuno-compromised hosts and methods of use
WO1995031998A1 (en) * 1994-05-23 1995-11-30 The Research & Development Institute, Inc. Candida albicans adhesin as a vaccine
US6488929B2 (en) 1994-05-23 2002-12-03 Montana State University Candida albicans phosphomannan complex as a vaccine
US6309642B1 (en) 1997-04-28 2001-10-30 The Research And Development Institute, Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
DE19631189A1 (de) * 1996-08-02 1998-02-05 Max Delbrueck Centrum Neuartige kationische Amphiphile für den liposomalen Gentransfer
US20030072775A1 (en) * 1997-04-28 2003-04-17 The Research And Development Institute Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
CN1301847A (zh) * 1999-12-27 2001-07-04 上海博德基因开发有限公司 一种新的多肽——脂肪氧化酶10和编码这种多肽的多核苷酸
CN1313389A (zh) * 2000-03-15 2001-09-19 上海博德基因开发有限公司 一种新的多肽——人脂肪氧化酶9和编码这种多肽的多核苷酸
EP2217224B1 (en) 2007-11-09 2019-05-08 Basf As Lipid compounds for use in cosmetic products, as food supplement or as a medicament
EP2147910A1 (en) * 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Novel lipid compounds
MX2011011614A (es) 2009-05-08 2011-11-18 Pronova Biopharma Norge As Acidos grasos poliinsaturados para el tratamiento de trastornos relacionados a las areas de los trastornos cardiovasculares, metabolicos e inflamatorios.
MX2012006877A (es) 2009-12-18 2012-08-31 Idenix Pharmaceuticals Inc Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
AU2011324909B2 (en) 2010-11-05 2016-09-08 Pronova Biopharma Norge As Methods of treatment using lipid compounds
CN105120842B (zh) 2013-02-28 2020-12-01 普罗诺瓦生物医药挪威公司 包含脂质化合物、甘油三酯和表面活性剂的组合物以及使用它们的方法
WO2016173923A1 (en) 2015-04-28 2016-11-03 Pronova Biopharma Norge As Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis
BR112020011431A2 (pt) 2017-12-06 2020-11-24 Basf As derivados de ácido graxo para o tratamento de esteato-hepatite não alcoólica

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288527A2 (fr) 1974-10-22 1976-05-21 Anvar Compositions contenant de la n-acetyl-muramyl- l-alanyl - d-isoglutamine ou de l'acide n-acetyl-muramyl-l-alanyl - d-glutamique, exemptes d'huile et ayant des proprietes adjuvantes
SE7607300L (sv) 1975-08-13 1977-02-14 Kefalas As Tiaxantenforeningar samt forfarande for framstellning av dem
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
JPS5479228A (en) * 1977-12-02 1979-06-25 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5479227A (en) * 1977-12-02 1979-06-25 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
EP0002677B1 (en) * 1977-12-02 1982-10-13 Takeda Chemical Industries, Ltd. Glucosamine-peptide derivatives and their pharmaceutical compositions
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
JPS54130517A (en) * 1978-03-31 1979-10-09 Yuuichi Yamamura Muramyldipeptide higher fatty acid ester
HU186585B (en) * 1978-05-18 1985-08-28 Ciba Geigy Ag Process for producing new muramil-peptide derivatives
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2449697A1 (fr) * 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation

Also Published As

Publication number Publication date
PT72866B (en) 1985-11-25
ATE23537T1 (de) 1986-11-15
EP0038750B1 (en) 1986-11-12
US4368190A (en) 1983-01-11
ES8207553A1 (es) 1982-09-16
JPS56164196A (en) 1981-12-17
PT72866A (en) 1981-05-01
CA1174232A (en) 1984-09-11
DE3175602D1 (en) 1987-01-02
EP0038750A1 (en) 1981-10-28
ES501457A0 (es) 1982-09-16
GR76828B (da) 1984-09-04

Similar Documents

Publication Publication Date Title
DK172481A (da) Fremgangsmaade til fremstilling af dipeptidyl-4-0-og-6-0-acyl-2-amino-2-deoxy-d-glucosederivater
GB1088531A (en) Substituted benzamides
JPS53119844A (en) Optically active amino acid-mandelic acid complexes and theire preparation
NO921281L (no) Piperidinderivater, fremgangsmaate for deres fremstilling og terapeutiske anvendelse
DK148183D0 (da) Fremgangsmade til fremstilling af imidazolylphenyl-tetrahydropyridaziner
DK152090D0 (da) Piperidylsubstituerede indolderivater
HUP0001396A2 (hu) 3-Amino-3 aril-propán-1-ol-származékok, előállításuk és felhasználásuk
ATE6863T1 (de) Dipeptid-derivate von 5-0,6-0-acyl-2-amin-2desoxy-d-glucofuranose und verfahren zur herstellung.
SE8207302L (sv) Nya 2-pyrrolidonforeningar och forfarande for framstellning av desamma
ES523415A0 (es) Un metodo para preparar compuestos de piridilo
NO983472L (no) Taxoider, deres fremstilling og farmas°ytiske preparater inneholdende taxoidene
DK152426C (da) Analogifremgangsmaade til fremstilling af alkoxyphenylpyrrolidoner eller farmaceutisk acceptable salte deraf
DK524283D0 (da) Fremgangsmade til fremstilling af nitrosoureaderivater
FI972530A (fi) Menetelmä substituoitujen 4-etyyli-piperidiinien valmistamiseksi ja niiden valmistuksessa käytettävä välituote
ES517042A0 (es) Procedimiento para la preparacion de una aroilimidazolidin-2-ona.
DK214589D0 (da) 3-substituerede 3-(thien-2-yl)-piperazin-2-oner eller farmakologisk acceptable syreadditionsforbindelser deraf, deres fremstilling og anvendelse
DK519783D0 (da) Fremgangsmade til fremstilling af 1-aroyl-5-oxo-2-pyrrolidinpropansyrer samt beslaegtede estre samt kompositioner indeholdende disse
ES2147825T3 (es) Derivados tetraciclicos de la 1,4-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
SE7907251L (sv) Nya metyl-l-piperidinol-4-estrar och sett att framstella dessa samt farmaceutiska kompositioner, innehallande nemnda estrar
EP0011845A3 (de) Haarbehandlungsmittel mit Antischuppenwirkung
SE8505858L (sv) Karbazater
JPS523081A (en) Preparation of sulfonylpyridazionones
PT96885A (pt) Processo para a preparacao de n-cicloalquilalquilaminas e de composicoes farmaceuticas que os contem
FI813139L (fi) Nya kefalosporin foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel
MY102115A (en) Pyridyl compounds

Legal Events

Date Code Title Description
ATS Application withdrawn
B1 Patent granted (law 1993)