DK1706390T3 - Isoxazolderivater og deres anvendelse som cyclo-oxygenase inhibitorer - Google Patents

Isoxazolderivater og deres anvendelse som cyclo-oxygenase inhibitorer

Info

Publication number
DK1706390T3
DK1706390T3 DK05702217.0T DK05702217T DK1706390T3 DK 1706390 T3 DK1706390 T3 DK 1706390T3 DK 05702217 T DK05702217 T DK 05702217T DK 1706390 T3 DK1706390 T3 DK 1706390T3
Authority
DK
Denmark
Prior art keywords
cyclo
isoxazole derivatives
oxygenase inhibitors
inhibitors
oxygenase
Prior art date
Application number
DK05702217.0T
Other languages
English (en)
Inventor
Antonio Scilimati
Nunno Leonardo Di
Paola Vitale
Paola Patrignani
Stefania Tacconelli
Ettore Porreca
Liborio Stuppia
Original Assignee
Uni Degli Studi Di Chieti
Univ Bari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi Di Chieti, Univ Bari filed Critical Uni Degli Studi Di Chieti
Application granted granted Critical
Publication of DK1706390T3 publication Critical patent/DK1706390T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK05702217.0T 2004-01-12 2005-01-12 Isoxazolderivater og deres anvendelse som cyclo-oxygenase inhibitorer DK1706390T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000019A ITMI20040019A1 (it) 2004-01-12 2004-01-12 Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
PCT/IB2005/000047 WO2005068442A2 (en) 2004-01-12 2005-01-12 Isoxazole derivatives and their use as cyclooxygenase inhibitors

Publications (1)

Publication Number Publication Date
DK1706390T3 true DK1706390T3 (da) 2010-08-23

Family

ID=34779432

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05702217.0T DK1706390T3 (da) 2004-01-12 2005-01-12 Isoxazolderivater og deres anvendelse som cyclo-oxygenase inhibitorer

Country Status (7)

Country Link
EP (2) EP1706390B1 (da)
AT (2) ATE538107T1 (da)
DE (1) DE602005021309D1 (da)
DK (1) DK1706390T3 (da)
ES (1) ES2344738T3 (da)
IT (1) ITMI20040019A1 (da)
WO (1) WO2005068442A2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943588B2 (en) 2006-03-28 2011-05-17 Trustees Of Dartmouth College Method for preventing or treating neuropathic pain
US7989450B2 (en) 2008-01-11 2011-08-02 Universita' Degli Studi Di Bari Functionalized diarylisoxazoles inhibitors of ciclooxygenase

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1128526A (en) * 1979-10-05 1982-07-27 Cdc Life Sciences Inc. 3,4-diarylisoxazol-5-acetic acids
JPH04134077A (ja) * 1990-09-21 1992-05-07 Taiho Yakuhin Kogyo Kk イソオキサゾール化合物
CA2102209C (en) * 1991-05-01 1997-11-18 Takashi Shindo Novel isoxazole derivative and salt thereof
CN1107058C (zh) * 1995-02-13 2003-04-30 G·D·瑟尔公司 用于治疗类症的取代的异噁唑
AU733091B2 (en) * 1997-04-21 2001-05-03 Dainippon Sumitomo Pharma Co., Ltd. Isoxazole derivatives
WO2001081332A2 (en) * 2000-04-25 2001-11-01 Pharmacia Corporation 2-fluorobenzenesulfonyl compounds for the treatment of inflammation
US20030105144A1 (en) * 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
US6673818B2 (en) * 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
US20030105334A1 (en) * 2001-10-02 2003-06-05 Letendre Leo J. Method for preparing benzenesulfonyl compounds
US6809204B2 (en) * 2001-10-12 2004-10-26 Onconova Therapeutics, Inc. Processes for the preparation of substituted isoxazoles and 2-isoxazolines
US20030232871A1 (en) * 2002-03-15 2003-12-18 Sheikh Ahmad Y. Crystalline parecoxib sodium
ES2321502T3 (es) * 2002-04-05 2009-06-08 Cadila Healthcare Limited Compuestos de 4-(heterociclil)-benzenosulfoximina para el tratamiento de la inflamacion.
DE10237883A1 (de) * 2002-08-19 2004-03-04 Merckle Gmbh Chem.-Pharm. Fabrik Substituierte Isoxazolderivate und ihre Verwendung in der Pharmazie
CA2503063A1 (en) * 2002-10-22 2004-05-06 Merck Frosst Canada & Co./Merck Frosst Canada & Cie Nitric oxide releasing selective cyclooxygenase-2 inhibitors
HUP0302219A2 (hu) * 2003-07-16 2005-03-29 Richter Gedeon Vegyészeti Gyár Rt. N-hidroxi-4-(3-fenil-5-metil-izoxazol-4-il)-benzolszulfonamid-szolvátok, eljárás előállításukra és alkalmazásuk

Also Published As

Publication number Publication date
EP1706390A2 (en) 2006-10-04
EP2246337A1 (en) 2010-11-03
ITMI20040019A1 (it) 2004-04-12
WO2005068442A2 (en) 2005-07-28
ATE468329T1 (de) 2010-06-15
ES2344738T3 (es) 2010-09-06
EP1706390B1 (en) 2010-05-19
ATE538107T1 (de) 2012-01-15
WO2005068442A3 (en) 2006-04-06
EP2246337B1 (en) 2011-12-21
DE602005021309D1 (de) 2010-07-01

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