DK169731B1 - Carbolinderivater, farmaceutiske præparater som indeholder dem, fremgangsmåde til fremstilling af disse præparater samt fremgangsmåde til fremstilling af carbolinderivaterne - Google Patents
Carbolinderivater, farmaceutiske præparater som indeholder dem, fremgangsmåde til fremstilling af disse præparater samt fremgangsmåde til fremstilling af carbolinderivaterne Download PDFInfo
- Publication number
- DK169731B1 DK169731B1 DK294989A DK294989A DK169731B1 DK 169731 B1 DK169731 B1 DK 169731B1 DK 294989 A DK294989 A DK 294989A DK 294989 A DK294989 A DK 294989A DK 169731 B1 DK169731 B1 DK 169731B1
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- group
- methylene chloride
- pyrrolo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/16—Peri-condensed systems
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8801565 | 1988-06-20 | ||
NL8801565 | 1988-06-20 | ||
NL8900136 | 1989-01-20 | ||
NL8900136 | 1989-01-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK294989D0 DK294989D0 (da) | 1989-06-15 |
DK294989A DK294989A (da) | 1989-12-21 |
DK169731B1 true DK169731B1 (da) | 1995-01-30 |
Family
ID=26646394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK294989A DK169731B1 (da) | 1988-06-20 | 1989-06-15 | Carbolinderivater, farmaceutiske præparater som indeholder dem, fremgangsmåde til fremstilling af disse præparater samt fremgangsmåde til fremstilling af carbolinderivaterne |
Country Status (8)
Country | Link |
---|---|
US (1) | US5332746A (ja) |
EP (1) | EP0347980A1 (ja) |
JP (1) | JPH0245485A (ja) |
AU (1) | AU628059B2 (ja) |
CA (1) | CA1338190C (ja) |
DK (1) | DK169731B1 (ja) |
IL (1) | IL90652A (ja) |
NZ (1) | NZ229587A (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0357122A3 (en) * | 1988-08-29 | 1991-10-23 | Duphar International Research B.V | Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties |
US5663178A (en) * | 1995-02-06 | 1997-09-02 | Eli Lilly And Company | Tetrahydro-beta carbolines |
IL145998A0 (en) * | 1999-06-15 | 2002-07-25 | Du Pont Pharm Co | Substituted heterocycle fused gamma-carbolines |
US8563567B2 (en) | 2009-12-30 | 2013-10-22 | Arqule, Inc. | Substituted heterocyclic compounds |
US10092550B2 (en) | 2014-10-21 | 2018-10-09 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof |
US9907786B2 (en) | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
US10947253B2 (en) | 2019-08-05 | 2021-03-16 | Ankh Life Sciences Limited | Fused polycyclic dimers |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES273769A1 (es) * | 1961-01-18 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico |
DD129791A5 (de) * | 1976-04-13 | 1978-02-08 | Synthelabo | Verfahren zur herstellung von naphtyridinderivaten |
GB2005267B (en) * | 1977-09-30 | 1982-05-19 | Omnium Chimique Sa | Indole derivatives their preparation and pharmaceutical compositions containing them |
NL189463C (nl) * | 1978-12-28 | 1993-04-16 | Omnichem Sa | Indolonaftyridinederivaten, werkwijze voor het bereiden daarvan en geneesmiddel voor de behandeling van cardiocirculatore en cerebrovasculaire aandoeningen. |
LU84664A1 (fr) * | 1983-02-25 | 1984-11-08 | Onmichem S A | Alkyl-4-indolonaphtyridines et leur application therapeutique |
DE3855147D1 (de) * | 1987-07-20 | 1996-05-02 | Duphar Int Res | 8,9-Anellierte 1,2,3,4-Tetrahydro-beta-carbolin-Derivate |
DK686688A (da) * | 1987-12-14 | 1989-06-15 | Duphar Int Res | 8,9-annelerede beta-carboliner, deres fremstilling og laegemidler indeholdende forbindelserne |
EP0357122A3 (en) * | 1988-08-29 | 1991-10-23 | Duphar International Research B.V | Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties |
-
1989
- 1989-06-14 EP EP89201538A patent/EP0347980A1/en not_active Withdrawn
- 1989-06-15 CA CA000602836A patent/CA1338190C/en not_active Expired - Fee Related
- 1989-06-15 DK DK294989A patent/DK169731B1/da not_active IP Right Cessation
- 1989-06-16 AU AU36501/89A patent/AU628059B2/en not_active Ceased
- 1989-06-16 NZ NZ229587A patent/NZ229587A/en unknown
- 1989-06-19 IL IL90652A patent/IL90652A/xx not_active IP Right Cessation
- 1989-06-20 JP JP1155920A patent/JPH0245485A/ja active Pending
-
1991
- 1991-05-08 US US07/700,058 patent/US5332746A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU3650189A (en) | 1989-12-21 |
IL90652A0 (en) | 1990-01-18 |
JPH0245485A (ja) | 1990-02-15 |
NZ229587A (en) | 1991-05-28 |
DK294989A (da) | 1989-12-21 |
AU628059B2 (en) | 1992-09-10 |
US5332746A (en) | 1994-07-26 |
IL90652A (en) | 1993-08-18 |
EP0347980A1 (en) | 1989-12-27 |
DK294989D0 (da) | 1989-06-15 |
CA1338190C (en) | 1996-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |