DK166278C - Triazinsalt, fremgangsmaade til dets fremstilling og farmaceutisk komposition indeholdende saltet - Google Patents

Triazinsalt, fremgangsmaade til dets fremstilling og farmaceutisk komposition indeholdende saltet

Info

Publication number
DK166278C
DK166278C DK275987A DK275987A DK166278C DK 166278 C DK166278 C DK 166278C DK 275987 A DK275987 A DK 275987A DK 275987 A DK275987 A DK 275987A DK 166278 C DK166278 C DK 166278C
Authority
DK
Denmark
Prior art keywords
salt
triazin
procedure
preparation
pharmaceutical composition
Prior art date
Application number
DK275987A
Other languages
Danish (da)
English (en)
Other versions
DK275987A (da
DK166278B (da
DK275987D0 (da
Inventor
David Alan Sawyer
Frederick Charles Copp
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK275987D0 publication Critical patent/DK275987D0/da
Publication of DK275987A publication Critical patent/DK275987A/da
Publication of DK166278B publication Critical patent/DK166278B/da
Application granted granted Critical
Publication of DK166278C publication Critical patent/DK166278C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK275987A 1986-05-30 1987-05-29 Triazinsalt, fremgangsmaade til dets fremstilling og farmaceutisk komposition indeholdende saltet DK166278C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8613183 1986-05-30
GB868613183A GB8613183D0 (en) 1986-05-30 1986-05-30 Triazine salt

Publications (4)

Publication Number Publication Date
DK275987D0 DK275987D0 (da) 1987-05-29
DK275987A DK275987A (da) 1987-12-01
DK166278B DK166278B (da) 1993-03-29
DK166278C true DK166278C (da) 1993-08-23

Family

ID=10598692

Family Applications (1)

Application Number Title Priority Date Filing Date
DK275987A DK166278C (da) 1986-05-30 1987-05-29 Triazinsalt, fremgangsmaade til dets fremstilling og farmaceutisk komposition indeholdende saltet

Country Status (18)

Country Link
US (1) US4847249A (de)
EP (1) EP0247892B1 (de)
JP (1) JPH0751571B2 (de)
KR (1) KR910002254B1 (de)
AT (1) ATE62902T1 (de)
AU (1) AU597982B2 (de)
CA (1) CA1286670C (de)
DE (1) DE3769516D1 (de)
DK (1) DK166278C (de)
ES (1) ES2021709B3 (de)
FI (1) FI90770C (de)
GB (1) GB8613183D0 (de)
GR (1) GR3001942T3 (de)
HU (1) HU196769B (de)
IE (1) IE60626B1 (de)
IL (1) IL82710A (de)
NZ (1) NZ220497A (de)
ZA (1) ZA873896B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9012312D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB9124807D0 (en) * 1991-11-22 1992-01-15 Wellcome Found Pharmaceutical formulations
MY110880A (en) * 1991-01-30 1999-06-30 The Wellcome Foundation Ltd Water-dispersible tablets
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB9203483D0 (en) * 1992-02-19 1992-04-08 Wellcome Found Anti-inflammatory compounds
ES2097516T3 (es) * 1992-06-12 1997-04-01 Wellcome Found Uso de isetionato de 3,5-diamino-6-(2,3-diclorofenil)-1,2,4-triazina para el tratamiento y prevencion de la dependencia, tolerancia y sensibilidad a los farmacos y drogas.
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2699078B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application de la lamotrigine dans le traitement de lésions neurologiques liées à des traumatismes.
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
FR2700117B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
FR2702148B1 (fr) * 1993-03-05 1995-04-07 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement du neuro-sida.
GB9305693D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
US5866597A (en) * 1993-03-19 1999-02-02 Glaxo Wellcome Inc. Use of triazine compounds for the treatment of memory and learning disorders
GB9306639D0 (en) * 1993-03-30 1993-05-26 Tocris Neuramin Limited Organic compounds
FR2702149B1 (fr) * 1993-06-03 1995-04-07 Rhone Poulenc Rorer Sa Application de la lamotrigine dans le traitement du neuro-sida.
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
EP0800520B1 (de) * 1994-12-30 2002-06-19 The Wellcome Foundation Limited Verfahren zur herstellung von lamotrigine
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
GB9812413D0 (en) 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
AU1292400A (en) * 1998-12-14 2000-07-03 Sharad Kumar Vyas An improved process for the preparation of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
WO2001049669A1 (en) * 2000-01-03 2001-07-12 Rpg Life Sciences Limited A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine
IL134730A (en) * 2000-02-25 2003-10-31 Chemagis Ltd Process for preparing substituted benzoyl cyanide amidinohydrazones
IL157608A0 (en) * 2001-02-27 2004-03-28 Teva Pharma New crystal forms of lamotrigine and processes for their preparations
CA2483103A1 (en) * 2002-04-23 2003-11-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing lamotrigine particles of defined morphology
HU225667B1 (en) * 2002-09-20 2007-05-29 Richter Gedeon Nyrt Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
ES2209639B1 (es) 2002-10-31 2005-08-01 Vita Cientifica, S.L. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio.
GB2395483A (en) * 2003-07-03 2004-05-26 Jubilant Organosys Ltd Crystalline lamotrigine and its monohydrate
US8486927B2 (en) 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine
US12605388B2 (en) 2024-09-25 2026-04-21 Azurity Pharmaceuticals Ireland Limited Lamotrigine salts, co-crystals, and compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153787C (da) * 1979-06-01 1989-01-16 Wellcome Found Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved
DE3069556D1 (en) * 1979-08-16 1984-12-06 Wellcome Found Solid pharmaceutical formulation containing substitued phenyl-triazines
EP0093186B1 (de) * 1982-05-03 1986-07-09 Richardson Vicks Limited Pharmazeutisches Präparat zur topischen Behandlung von Akne
GB8328757D0 (en) * 1983-10-27 1983-11-30 Wellcome Found Chemical compounds

Also Published As

Publication number Publication date
IL82710A0 (en) 1987-11-30
KR870011112A (ko) 1987-12-21
DK275987A (da) 1987-12-01
JPH0751571B2 (ja) 1995-06-05
EP0247892A1 (de) 1987-12-02
ATE62902T1 (de) 1991-05-15
ES2021709B3 (es) 1991-11-16
HUT45978A (en) 1988-09-28
US4847249A (en) 1989-07-11
NZ220497A (en) 1990-05-28
AU597982B2 (en) 1990-06-14
GB8613183D0 (en) 1986-07-02
FI872406L (fi) 1987-12-01
DE3769516D1 (de) 1991-05-29
DK166278B (da) 1993-03-29
FI90770C (fi) 1994-03-25
FI90770B (fi) 1993-12-15
IE60626B1 (en) 1994-07-27
IL82710A (en) 1992-01-15
EP0247892B1 (de) 1991-04-24
AU7368487A (en) 1987-12-03
DK275987D0 (da) 1987-05-29
CA1286670C (en) 1991-07-23
ZA873896B (en) 1989-01-25
IE871415L (en) 1987-11-30
GR3001942T3 (en) 1992-11-23
HU196769B (en) 1989-01-30
JPS62289570A (ja) 1987-12-16
KR910002254B1 (ko) 1991-04-08
FI872406A0 (fi) 1987-05-29

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