DK165985C - 1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler - Google Patents

1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler

Info

Publication number
DK165985C
DK165985C DK227388A DK227388A DK165985C DK 165985 C DK165985 C DK 165985C DK 227388 A DK227388 A DK 227388A DK 227388 A DK227388 A DK 227388A DK 165985 C DK165985 C DK 165985C
Authority
DK
Denmark
Prior art keywords
preparation
cytosin
procedures
derivatives
medicinal products
Prior art date
Application number
DK227388A
Other languages
Danish (da)
English (en)
Other versions
DK227388D0 (da
DK165985B (da
DK227388A (da
Inventor
Peter James Machin
Joseph Armstrong Martin
Gareth John Thomas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK227388D0 publication Critical patent/DK227388D0/da
Publication of DK227388A publication Critical patent/DK227388A/da
Publication of DK165985B publication Critical patent/DK165985B/da
Application granted granted Critical
Publication of DK165985C publication Critical patent/DK165985C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK227388A 1987-05-22 1988-04-26 1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler DK165985C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712115A GB8712115D0 (en) 1987-05-22 1987-05-22 Pyrimidine derivatives
GB8712115 1987-05-22

Publications (4)

Publication Number Publication Date
DK227388D0 DK227388D0 (da) 1988-04-26
DK227388A DK227388A (da) 1988-11-23
DK165985B DK165985B (da) 1993-02-22
DK165985C true DK165985C (da) 1993-11-08

Family

ID=10617762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK227388A DK165985C (da) 1987-05-22 1988-04-26 1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler

Country Status (19)

Country Link
EP (1) EP0292023A3 (sh)
JP (1) JPS63303992A (sh)
KR (1) KR880013927A (sh)
CN (1) CN88103089A (sh)
AU (1) AU602083B2 (sh)
DK (1) DK165985C (sh)
FI (1) FI882303A (sh)
GB (1) GB8712115D0 (sh)
HU (1) HU199868B (sh)
IL (1) IL86394A0 (sh)
IS (1) IS3344A7 (sh)
MC (1) MC1934A1 (sh)
MX (1) MX11493A (sh)
NO (1) NO171065C (sh)
NZ (1) NZ224638A (sh)
PH (1) PH26909A (sh)
PT (1) PT87550B (sh)
YU (1) YU46860B (sh)
ZA (1) ZA883447B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340645C (en) * 1987-04-17 1999-07-13 Victor E. Marquez Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
GR1000618B (el) * 1989-03-17 1992-08-31 Oncogen Μεθοδος αναστολης hiv χρησιμοποιωντας συνεργιστικους συνδυασμους νουκλεοσιδικων παραγωγων.
WO1991006554A1 (en) * 1989-11-06 1991-05-16 Nycomed As Nucleoside derivatives
AT400953B (de) * 1994-08-25 1996-05-28 Joern Saischek Pentofuranosid-derivate, deren herstellung und verwendung
ES2276515T3 (es) 1998-02-25 2007-06-16 Emory University 2'-fluoronucleosidos.
EP1411954B1 (en) 2000-10-18 2010-12-15 Pharmasset, Inc. Modified nucleosides for treatment of viral infections and abnormal cellular proliferation
AU2002322325A1 (en) 2001-06-22 2003-01-08 Emory University Beta-2'-or 3'-halonucleosides
DE602005015466D1 (de) 2004-08-23 2009-08-27 Hoffmann La Roche Antivirale 4'-azidonucleoside
US8895531B2 (en) 2006-03-23 2014-11-25 Rfs Pharma Llc 2′-fluoronucleoside phosphonates as antiviral agents
ES2392948T3 (es) 2006-10-10 2012-12-17 Janssen Products, L.P. Intermedio para inhibidores nucleosídicos de VHC

Also Published As

Publication number Publication date
KR880013927A (ko) 1988-12-22
FI882303A (fi) 1988-11-23
IS3344A7 (is) 1988-11-23
CN88103089A (zh) 1988-12-07
EP0292023A3 (de) 1989-06-14
PT87550B (pt) 1992-09-30
GB8712115D0 (en) 1987-06-24
JPS63303992A (ja) 1988-12-12
AU1631788A (en) 1988-11-24
PH26909A (en) 1992-12-03
EP0292023A2 (de) 1988-11-23
NZ224638A (en) 1990-04-26
FI882303A0 (fi) 1988-05-17
HU199868B (en) 1990-03-28
NO882233L (no) 1988-11-23
HUT47127A (en) 1989-01-30
AU602083B2 (en) 1990-09-27
MX11493A (es) 1993-09-01
ZA883447B (en) 1988-11-22
DK227388D0 (da) 1988-04-26
NO882233D0 (no) 1988-05-20
IL86394A0 (en) 1988-11-15
NO171065C (no) 1993-01-20
YU93288A (en) 1990-04-30
NO171065B (no) 1992-10-12
DK165985B (da) 1993-02-22
DK227388A (da) 1988-11-23
YU46860B (sh) 1994-06-24
PT87550A (pt) 1989-05-31
MC1934A1 (fr) 1989-05-19

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