DK165452C - 7-0-(2,6-dideoxy-2-fluor-alfa-l-talopyranosyl)-adriamycinon-14-0-acylderivater, deres fremstilling og anvendelse - Google Patents

7-0-(2,6-dideoxy-2-fluor-alfa-l-talopyranosyl)-adriamycinon-14-0-acylderivater, deres fremstilling og anvendelse

Info

Publication number
DK165452C
DK165452C DK638787A DK638787A DK165452C DK 165452 C DK165452 C DK 165452C DK 638787 A DK638787 A DK 638787A DK 638787 A DK638787 A DK 638787A DK 165452 C DK165452 C DK 165452C
Authority
DK
Denmark
Prior art keywords
preparation
adriamycinon
talopyranosyl
dideoxy
alfa
Prior art date
Application number
DK638787A
Other languages
Danish (da)
English (en)
Other versions
DK638787D0 (da
DK165452B (da
DK638787A (da
Inventor
Hamao Umezawa
Sumio Umezawa
Tsutomu Tsuchiya
Tomio Takeuchi
Yasushi Takagi
Toshio Yoneda
Shunzo Fukatsu
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of DK638787D0 publication Critical patent/DK638787D0/da
Publication of DK638787A publication Critical patent/DK638787A/da
Publication of DK165452B publication Critical patent/DK165452B/da
Application granted granted Critical
Publication of DK165452C publication Critical patent/DK165452C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK638787A 1986-12-05 1987-12-04 7-0-(2,6-dideoxy-2-fluor-alfa-l-talopyranosyl)-adriamycinon-14-0-acylderivater, deres fremstilling og anvendelse DK165452C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28899386 1986-12-05
JP61288993A JPH0742304B2 (ja) 1986-12-05 1986-12-05 新規なアンスラサイクリン誘導体およびその製造法

Publications (4)

Publication Number Publication Date
DK638787D0 DK638787D0 (da) 1987-12-04
DK638787A DK638787A (da) 1988-06-06
DK165452B DK165452B (da) 1992-11-30
DK165452C true DK165452C (da) 1993-04-13

Family

ID=17737453

Family Applications (1)

Application Number Title Priority Date Filing Date
DK638787A DK165452C (da) 1986-12-05 1987-12-04 7-0-(2,6-dideoxy-2-fluor-alfa-l-talopyranosyl)-adriamycinon-14-0-acylderivater, deres fremstilling og anvendelse

Country Status (11)

Country Link
EP (1) EP0275431B1 (de)
JP (1) JPH0742304B2 (de)
KR (1) KR880007556A (de)
AT (1) ATE80890T1 (de)
CA (1) CA1295326C (de)
DE (1) DE3781879T2 (de)
DK (1) DK165452C (de)
ES (1) ES2044900T3 (de)
GR (1) GR3006438T3 (de)
IE (1) IE61308B1 (de)
PT (1) PT86282B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0335369A3 (de) * 1988-03-29 1990-03-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Anthracyclin-Derivate und Verfahren zu deren Herstellung
JPH0742232B2 (ja) * 1989-03-02 1995-05-10 明治製菓株式会社 制癌剤組成物
US5220001A (en) * 1989-10-25 1993-06-15 Zaidan Hojim Biseibutsu Dong-A Pharm Co. Anthracycline glycoside derivatives
KR100211417B1 (ko) * 1990-11-30 1999-10-01 유충식 L-탈로피라노시드 유도체 및 그의 제조방법
DE69509377T2 (de) * 1994-03-11 1999-11-18 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokio/Tokyo Anthracyclin-derivate, die ein trifluormethylierte zuckereinheiten enthalten
ES2134576T3 (es) * 1995-09-08 1999-10-01 Zaidan Hojin Biseibutsu Derivados de antraciclina que contienen fluor, que tienen grupo(s) hidroxilo mono- o di-o-aminoalquilados en su radical de azucar.
KR19990084528A (ko) * 1998-05-07 1999-12-06 박상철 신규 안트라사이클린 유도체 및 제조방법
BR112021003156A2 (pt) 2018-08-23 2021-05-11 Seagen, Inc. composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79729B (de) * 1982-12-20 1984-10-31 Univ Ohio State Res Found

Also Published As

Publication number Publication date
DK638787D0 (da) 1987-12-04
ES2044900T3 (es) 1994-01-16
IE873301L (en) 1988-06-05
DK165452B (da) 1992-11-30
ATE80890T1 (de) 1992-10-15
DE3781879T2 (de) 1993-04-08
CA1295326C (en) 1992-02-04
JPS63141992A (ja) 1988-06-14
EP0275431A1 (de) 1988-07-27
KR880007556A (ko) 1988-08-27
DE3781879D1 (de) 1992-10-29
IE61308B1 (en) 1994-10-19
DK638787A (da) 1988-06-06
PT86282B (pt) 1990-11-07
PT86282A (en) 1988-01-01
JPH0742304B2 (ja) 1995-05-10
GR3006438T3 (de) 1993-06-21
EP0275431B1 (de) 1992-09-23

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Legal Events

Date Code Title Description
PBP Patent lapsed