DK165325C - Analogifremgangsmaade til fremstilling af 4-aza-17-substituerede 5alfa-androstan-3-oner - Google Patents

Analogifremgangsmaade til fremstilling af 4-aza-17-substituerede 5alfa-androstan-3-oner

Info

Publication number
DK165325C
DK165325C DK152579A DK152579A DK165325C DK 165325 C DK165325 C DK 165325C DK 152579 A DK152579 A DK 152579A DK 152579 A DK152579 A DK 152579A DK 165325 C DK165325 C DK 165325C
Authority
DK
Denmark
Prior art keywords
5alfa
androstan
aza
ones
substituted
Prior art date
Application number
DK152579A
Other languages
Danish (da)
English (en)
Other versions
DK165325B (da
DK152579A (da
Inventor
Gary H Rasmusson
David B R Johnston
Donald F Reinhold
Torleif Utne
Ronald B Jobson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK152579A publication Critical patent/DK152579A/da
Publication of DK165325B publication Critical patent/DK165325B/da
Application granted granted Critical
Publication of DK165325C publication Critical patent/DK165325C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016Oximes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J11/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J33/00Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007Cyclic thioketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J73/00Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK152579A 1978-04-13 1979-04-11 Analogifremgangsmaade til fremstilling af 4-aza-17-substituerede 5alfa-androstan-3-oner DK165325C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89612078 1978-04-13
US05/896,120 US4179453A (en) 1978-04-13 1978-04-13 Process for preparing 17β-carboxy-5-androsten-3-ones

Publications (3)

Publication Number Publication Date
DK152579A DK152579A (da) 1979-10-14
DK165325B DK165325B (da) 1992-11-09
DK165325C true DK165325C (da) 1993-03-29

Family

ID=25405660

Family Applications (2)

Application Number Title Priority Date Filing Date
DK152579A DK165325C (da) 1978-04-13 1979-04-11 Analogifremgangsmaade til fremstilling af 4-aza-17-substituerede 5alfa-androstan-3-oner
DK092192A DK92192A (da) 1978-04-13 1992-07-15 Fremgangsmaade til fremstilling af a-homo-androstaner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK092192A DK92192A (da) 1978-04-13 1992-07-15 Fremgangsmaade til fremstilling af a-homo-androstaner

Country Status (11)

Country Link
US (1) US4179453A (pt)
AR (7) AR231991A1 (pt)
AT (1) AT377767B (pt)
DK (2) DK165325C (pt)
ES (1) ES479576A1 (pt)
FI (1) FI67389C (pt)
GR (1) GR68531B (pt)
NO (1) NO153141C (pt)
PL (2) PL126826B1 (pt)
PT (1) PT69451A (pt)
YU (1) YU86879A (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237061A (en) * 1988-10-31 1993-08-17 Merck & Co., Inc. Methods of synthesizing benign prostatic hypertropic agents and their intermediates
US4937237A (en) * 1988-12-23 1990-06-26 Smithkline Beckman Corporation Phosphinic acid substituted aromatic steroids as inhibitors of steroid 5-60 -reductase
US4970205A (en) * 1988-12-23 1990-11-13 Smithkline Beecham Corporation Sulfonic acid substituted aromatic steroids as inhibitors of steroid 5-α-reductase
US5360881A (en) * 1989-06-14 1994-11-01 Societe Francaise Hoechst Method of cross-linking ethylene monomers using diallyloxyacetic acid and its basic addition salts as cross-linking agents
IE76452B1 (en) * 1990-10-29 1997-10-22 Sankyo Co Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use
FR2724174B1 (fr) * 1994-09-06 1997-01-17 Roussel Uclaf Procede de preparation d'un derive steroide 17beta-carboxy et nouveaux intermediaires

Also Published As

Publication number Publication date
AR224011A1 (es) 1981-10-15
AR228037A1 (es) 1983-01-14
DK165325B (da) 1992-11-09
AR222391A1 (es) 1981-05-15
US4179453A (en) 1979-12-18
PL214881A1 (pt) 1981-12-11
FI67389B (fi) 1984-11-30
DK92192D0 (da) 1992-07-15
AR241488A1 (es) 1992-07-31
PL223577A1 (pt) 1981-11-27
AR222390A1 (es) 1981-05-15
AR231991A1 (es) 1985-04-30
PL126826B1 (en) 1983-09-30
NO153141C (no) 1986-01-22
ES479576A1 (es) 1979-12-01
DK92192A (da) 1992-07-15
NO791220L (no) 1979-10-16
AR225045A1 (es) 1982-02-15
FI67389C (fi) 1985-03-11
FI791193A (fi) 1979-10-14
AT377767B (de) 1985-04-25
DK152579A (da) 1979-10-14
GR68531B (pt) 1982-01-14
NO153141B (no) 1985-10-14
PT69451A (en) 1979-05-01
YU86879A (en) 1983-10-31
ATA275079A (de) 1984-09-15

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Legal Events

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PBP Patent lapsed
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