DK1641438T3 - Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel - Google Patents

Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel

Info

Publication number
DK1641438T3
DK1641438T3 DK05758626.5T DK05758626T DK1641438T3 DK 1641438 T3 DK1641438 T3 DK 1641438T3 DK 05758626 T DK05758626 T DK 05758626T DK 1641438 T3 DK1641438 T3 DK 1641438T3
Authority
DK
Denmark
Prior art keywords
amorphous form
drug
preparing
preparation
active pharmaceutical
Prior art date
Application number
DK05758626.5T
Other languages
English (en)
Inventor
Claude Singer
Valerie Niddam-Hildesheim
Greta Sterimbaum
Szabolcs Szoke
Csaba Szabo
Lorant Gyuricza
Original Assignee
Teva Gyogyszergyar Zartkoeruen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Gyogyszergyar Zartkoeruen filed Critical Teva Gyogyszergyar Zartkoeruen
Application granted granted Critical
Publication of DK1641438T3 publication Critical patent/DK1641438T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/12Machines or apparatus for drying solid materials or objects with movement which is non-progressive in stationary drums or other mainly-closed receptacles with moving stirring devices
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/041Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum for drying flowable materials, e.g. suspensions, bulk goods, in a continuous operation, e.g. with locks or other air tight arrangements for charging/discharging

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK05758626.5T 2004-06-01 2005-06-01 Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel DK1641438T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57621604P 2004-06-01 2004-06-01
US58377804P 2004-06-28 2004-06-28
US59970004P 2004-08-05 2004-08-05
PCT/US2005/019485 WO2005117837A1 (en) 2004-06-01 2005-06-01 Process for preparation of amorphous form of a drug

Publications (1)

Publication Number Publication Date
DK1641438T3 true DK1641438T3 (da) 2010-06-07

Family

ID=35134738

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05758626.5T DK1641438T3 (da) 2004-06-01 2005-06-01 Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel

Country Status (11)

Country Link
US (1) US7589128B2 (da)
JP (1) JP2008500405A (da)
KR (1) KR20060123772A (da)
AT (1) ATE458476T1 (da)
CA (1) CA2560984A1 (da)
DE (1) DE602005019509D1 (da)
DK (1) DK1641438T3 (da)
ES (1) ES2339682T3 (da)
IL (1) IL179719A0 (da)
MX (1) MXPA06010084A (da)
WO (1) WO2005117837A1 (da)

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US20060083784A1 (en) * 2002-08-07 2006-04-20 Smithkline Beecham Corporation Amorphous pharmaceutical compositions
JP2008503595A (ja) 2004-10-15 2008-02-07 テバ ファーマシューティカル インダストリーズ リミティド テルミサルタンの調製方法
MX2007005348A (es) * 2004-11-03 2007-06-25 Teva Pharma Formas amorfas y polimorficas de sodio de telmisartan.
EP1817315A1 (en) * 2004-12-01 2007-08-15 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Processes for producing crystalline macrolides
WO2006079921A2 (en) 2005-01-28 2006-08-03 Pfizer Products Inc. Drying of drug-containing particles
EP1904448B1 (en) 2005-07-05 2011-02-02 Teva Pharmaceutical Industries, Ltd. Purification of montelukast
US20070161796A1 (en) * 2005-11-16 2007-07-12 Ilan Kor-Sade Drying methods of montelukast sodium by azeotropic removal of the solvent
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
PT2043610E (pt) 2006-07-21 2015-10-22 Bend Res Inc Secagem de partículas contendo fármacos
GB2441328A (en) * 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium
US20080187684A1 (en) * 2007-02-07 2008-08-07 Imra America, Inc. Method for depositing crystalline titania nanoparticles and films
WO2009070307A1 (en) * 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Amorphous retapamulin and processes for preparation thereof
GB2457452B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV)
EP2366378A1 (en) 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Sustained-release donepezil formulations
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
US8471030B2 (en) 2010-12-06 2013-06-25 Orochem Technologies Inc. Purification of montelukast using simulated moving bed
CA3111275A1 (en) 2018-09-06 2020-03-12 Innopharmascreen Inc. Methods and compositions for treatment of asthma or parkinson's disease

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JPS5270083A (en) 1975-12-04 1977-06-10 Yoshitomi Pharmaceut Ind Ltd Manufacture of an antibiotics, trans-pseudomonic acid
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HUP0600679A2 (en) 2001-12-28 2008-06-30 Biogal Gyogyszergyar Processes for preparing crystalline and amorphous mupirocin calcium and pharmaceutical compositions containing the same
RU2278659C9 (ru) 2002-02-01 2007-02-20 Пфайзер Продактс Инк. Способ получения гомогенных, высушенных распылением твердых аморфных дисперсий лекарственного средства с использованием модифицированной установки сушки распылением
EP1469830A2 (en) 2002-02-01 2004-10-27 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles
IL150907A (en) 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
EP1817315A1 (en) 2004-12-01 2007-08-15 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Processes for producing crystalline macrolides

Also Published As

Publication number Publication date
ES2339682T3 (es) 2010-05-24
CA2560984A1 (en) 2005-12-15
JP2008500405A (ja) 2008-01-10
US7589128B2 (en) 2009-09-15
MXPA06010084A (es) 2007-03-01
DE602005019509D1 (de) 2010-04-08
KR20060123772A (ko) 2006-12-04
WO2005117837A1 (en) 2005-12-15
ATE458476T1 (de) 2010-03-15
IL179719A0 (en) 2007-05-15
US20050272768A1 (en) 2005-12-08

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