MX2007005348A - Formas amorfas y polimorficas de sodio de telmisartan. - Google Patents

Formas amorfas y polimorficas de sodio de telmisartan.

Info

Publication number
MX2007005348A
MX2007005348A MX2007005348A MX2007005348A MX2007005348A MX 2007005348 A MX2007005348 A MX 2007005348A MX 2007005348 A MX2007005348 A MX 2007005348A MX 2007005348 A MX2007005348 A MX 2007005348A MX 2007005348 A MX2007005348 A MX 2007005348A
Authority
MX
Mexico
Prior art keywords
amorphous
telmisartan sodium
polymorphic forms
telmisartan
sodium
Prior art date
Application number
MX2007005348A
Other languages
English (en)
Inventor
Shlomit Wizel
Sharon Avhar-Maydan
Nurit Perlman
Eyal Gilboa
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of MX2007005348A publication Critical patent/MX2007005348A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Se proporciona la forma amorfa de sodio de telmisartan y la preparacion de ella. Tambien se proporcionan las formas 0 a XIII y XV a XX cristalinas polimorfas de sodio de telmisartan y las preparaciones de ellas. Tambien se proporcionan composiciones farmaceuticas de las formas amorfas y polimorficas de sodio de telmisartan o mezclas de ellas, y metodos de tratamiento de un mamifero que lo necesita.
MX2007005348A 2004-11-03 2005-11-03 Formas amorfas y polimorficas de sodio de telmisartan. MX2007005348A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62484204P 2004-11-03 2004-11-03
US65224605P 2005-02-11 2005-02-11
PCT/US2005/040059 WO2006050509A2 (en) 2004-11-03 2005-11-03 Amorphous and polymorphic forms of telmisartan sodium

Publications (1)

Publication Number Publication Date
MX2007005348A true MX2007005348A (es) 2007-06-25

Family

ID=35788339

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007005348A MX2007005348A (es) 2004-11-03 2005-11-03 Formas amorfas y polimorficas de sodio de telmisartan.

Country Status (8)

Country Link
US (1) US20060293377A1 (es)
EP (1) EP1807400A2 (es)
JP (1) JP2008516001A (es)
KR (1) KR20070072588A (es)
CA (1) CA2583694A1 (es)
IL (1) IL182240A0 (es)
MX (1) MX2007005348A (es)
WO (1) WO2006050509A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006044648A1 (en) 2004-10-15 2006-04-27 Teva Pharmaceutical Industries Ltd. Process for preparing telmisartan
US20090030057A1 (en) * 2005-11-22 2009-01-29 Shlomit Wizel Pharmaceutical composition of telmisartan
SI22297A (sl) * 2006-06-23 2007-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Priprava soli telmisartana
CN101990434B (zh) * 2008-01-15 2013-07-31 西佳技术公司 用于治疗沙粒病毒感染的抗病毒药物
ES2415357T3 (es) 2009-06-19 2013-07-25 Krka Tovarna Zdravil, D.D., Novo Mesto Procedimiento para la preparación de telmisartán
EA025946B1 (ru) 2010-10-27 2017-02-28 Крка, Товарна Здравил, Д. Д., Ново Место Многослойная фармацевтическая композиция, содержащая телмисартан и амлодипин
MX2021001169A (es) 2013-11-15 2023-02-10 Akebia Therapeutics Inc Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carb onil]amino}acético, composiciones, y usos de las mismas.
EP2979691A1 (en) * 2014-07-30 2016-02-03 Boehringer Ingelheim International GmbH Oral disintegrating tablet

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591762A (en) * 1991-02-06 1997-01-07 Dr. Karl Thomae Gmbh Benzimidazoles useful as angiotensin-11 antagonists
US6358986B1 (en) * 1999-01-19 2002-03-19 Boehringer Ingelheim Pharma Kg Polymorphs of telmisartan
DE10153737A1 (de) * 2001-10-31 2003-05-28 Boehringer Ingelheim Pharma Kristallines Natriumsalz des Telmisartans, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US6737432B2 (en) * 2001-10-31 2004-05-18 Boehringer Ingelheim Pharma Kg Crystalline form of telmisartan sodium
CN101352421A (zh) * 2002-01-16 2009-01-28 贝林格尔英格海姆法玛两合公司 一种制备基本上非结晶形式的替米沙坦的方法
US6770762B2 (en) * 2002-01-18 2004-08-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for preparing and purifying 1,7′-dimethyl-2′-propyl-2,5′-bi-1H-benzimidazole
GB0214224D0 (en) * 2002-06-20 2002-07-31 Strover Angus E Unicompartmental prosthetic knee joint device
DE10244681A1 (de) * 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
US9029363B2 (en) * 2003-04-30 2015-05-12 Boehringer Ingelheim International Gmbh Telmisartan sodium salt pharmaceutical formulation
CN1548421A (zh) * 2003-05-22 2004-11-24 上海医药工业研究院 替米沙坦盐及其制备方法
ATE458476T1 (de) * 2004-06-01 2010-03-15 Teva Gyogyszergyar Zartkoeruen Verfahren für die zubereitung der amorphen form eines medikamentes

Also Published As

Publication number Publication date
CA2583694A1 (en) 2006-05-11
IL182240A0 (en) 2007-09-20
WO2006050509A3 (en) 2006-08-03
KR20070072588A (ko) 2007-07-04
US20060293377A1 (en) 2006-12-28
WO2006050509A2 (en) 2006-05-11
JP2008516001A (ja) 2008-05-15
EP1807400A2 (en) 2007-07-18

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