DK1633355T3 - Benzothiazol-derivater og anvendelse deraf i behandlingen af sygdomme der er relateret til adenosin A2A-receptoren - Google Patents
Benzothiazol-derivater og anvendelse deraf i behandlingen af sygdomme der er relateret til adenosin A2A-receptorenInfo
- Publication number
- DK1633355T3 DK1633355T3 DK04734217T DK04734217T DK1633355T3 DK 1633355 T3 DK1633355 T3 DK 1633355T3 DK 04734217 T DK04734217 T DK 04734217T DK 04734217 T DK04734217 T DK 04734217T DK 1633355 T3 DK1633355 T3 DK 1633355T3
- Authority
- DK
- Denmark
- Prior art keywords
- adenosine
- receptor
- treatment
- diseases related
- benzothiazole derivatives
- Prior art date
Links
- 102000007471 Adenosine A2A receptor Human genes 0.000 title 1
- 108010085277 Adenosine A2A receptor Proteins 0.000 title 1
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03012118 | 2003-05-30 | ||
PCT/EP2004/005474 WO2004105755A1 (en) | 2003-05-30 | 2004-05-21 | Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine a2a receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1633355T3 true DK1633355T3 (da) | 2008-08-04 |
Family
ID=33442738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04734217T DK1633355T3 (da) | 2003-05-30 | 2004-05-21 | Benzothiazol-derivater og anvendelse deraf i behandlingen af sygdomme der er relateret til adenosin A2A-receptoren |
Country Status (27)
Country | Link |
---|---|
US (1) | US7285548B2 (sl) |
EP (1) | EP1633355B1 (sl) |
JP (1) | JP4426572B2 (sl) |
KR (1) | KR100765566B1 (sl) |
CN (1) | CN1798558B (sl) |
AR (1) | AR044569A1 (sl) |
AT (1) | ATE396726T1 (sl) |
AU (1) | AU2004243481B2 (sl) |
BR (1) | BRPI0410878A (sl) |
CA (1) | CA2527174C (sl) |
CL (1) | CL2004001272A1 (sl) |
DE (1) | DE602004014138D1 (sl) |
DK (1) | DK1633355T3 (sl) |
ES (1) | ES2307015T3 (sl) |
HR (1) | HRP20080318T3 (sl) |
IL (1) | IL171769A (sl) |
MX (1) | MXPA05012772A (sl) |
MY (1) | MY138018A (sl) |
NO (1) | NO20055176L (sl) |
NZ (1) | NZ543372A (sl) |
PL (1) | PL1633355T3 (sl) |
PT (1) | PT1633355E (sl) |
RU (1) | RU2348629C2 (sl) |
SI (1) | SI1633355T1 (sl) |
TW (1) | TW200508230A (sl) |
WO (1) | WO2004105755A1 (sl) |
ZA (1) | ZA200509608B (sl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2369256T3 (es) * | 2000-06-26 | 2011-11-28 | Helen Of Troy Limited | Sistema de lámpara recargable. |
MX2007000635A (es) * | 2004-07-22 | 2007-03-07 | Hoffmann La Roche | Benzotiazoles sustituidos. |
US8247609B2 (en) * | 2005-10-25 | 2012-08-21 | Pharamleads | Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase N inhibitors |
GB0622826D0 (en) * | 2006-11-15 | 2006-12-27 | Acurepharma Ab | Novel amides acting on the adenosine receptors |
WO2010140339A1 (ja) * | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
EP2934498B1 (en) | 2012-12-21 | 2017-11-15 | Janssen Sciences Ireland UC | Antibacterial compounds |
DE102019110904B4 (de) | 2019-04-26 | 2022-01-20 | Helmholtz-Zentrum Dresden - Rossendorf E. V. | N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE385794T1 (de) * | 2000-06-21 | 2008-03-15 | Hoffmann La Roche | Benzothiazolderivate zur behandlung von alzheimer und parkinson |
US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
-
2004
- 2004-05-21 EP EP04734217A patent/EP1633355B1/en not_active Expired - Lifetime
- 2004-05-21 JP JP2006508188A patent/JP4426572B2/ja not_active Expired - Fee Related
- 2004-05-21 MX MXPA05012772A patent/MXPA05012772A/es active IP Right Grant
- 2004-05-21 WO PCT/EP2004/005474 patent/WO2004105755A1/en active IP Right Grant
- 2004-05-21 SI SI200430752T patent/SI1633355T1/sl unknown
- 2004-05-21 PT PT04734217T patent/PT1633355E/pt unknown
- 2004-05-21 PL PL04734217T patent/PL1633355T3/pl unknown
- 2004-05-21 CN CN2004800148906A patent/CN1798558B/zh not_active Expired - Fee Related
- 2004-05-21 KR KR1020057022791A patent/KR100765566B1/ko active IP Right Grant
- 2004-05-21 CA CA2527174A patent/CA2527174C/en not_active Expired - Fee Related
- 2004-05-21 AT AT04734217T patent/ATE396726T1/de active
- 2004-05-21 AU AU2004243481A patent/AU2004243481B2/en not_active Ceased
- 2004-05-21 DK DK04734217T patent/DK1633355T3/da active
- 2004-05-21 DE DE602004014138T patent/DE602004014138D1/de not_active Expired - Lifetime
- 2004-05-21 ES ES04734217T patent/ES2307015T3/es not_active Expired - Lifetime
- 2004-05-21 RU RU2005141307/04A patent/RU2348629C2/ru not_active IP Right Cessation
- 2004-05-21 NZ NZ543372A patent/NZ543372A/en unknown
- 2004-05-21 BR BRPI0410878-7A patent/BRPI0410878A/pt not_active Application Discontinuation
- 2004-05-26 TW TW093114971A patent/TW200508230A/zh unknown
- 2004-05-26 US US10/854,059 patent/US7285548B2/en not_active Expired - Fee Related
- 2004-05-26 CL CL200401272A patent/CL2004001272A1/es unknown
- 2004-05-27 MY MYPI20042036A patent/MY138018A/en unknown
- 2004-05-28 AR ARP040101840A patent/AR044569A1/es not_active Application Discontinuation
-
2005
- 2005-11-03 IL IL171769A patent/IL171769A/en active IP Right Grant
- 2005-11-03 NO NO20055176A patent/NO20055176L/no unknown
- 2005-11-28 ZA ZA200509608A patent/ZA200509608B/en unknown
-
2008
- 2008-07-02 HR HR20080318T patent/HRP20080318T3/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1917246T3 (da) | Benzoquinazolinderivater og deres anvendelse til behandling af knoglesygdomme | |
NO20081842L (no) | Fremgangsmåter og sammensetninger for anvendelse ved behandling av pasienter med autoantistoff-positive sykdommer | |
DK1928886T3 (da) | Pyridin-derivater og deres anvendelse i behandlingen af psykotiske lidelser | |
NO20055204D0 (no) | Derivater av piperidinyl- og pipemzinylalkylkarbamater, fremgangsmater for fremstilling derav og anvendelse av de samme i terapi | |
DK1673104T3 (da) | Fremføring af terapeutiske forbindelser til hjernen og andre væv | |
DK1765322T3 (da) | Retinal-derivater og fremgangsmåder til anvendelse deraf i behandlingen af synsforstyrrelser | |
DK1578755T3 (da) | Phosphonooxyguinalinderivater og deres farmaceutiske anvendelse | |
IS7348A (is) | N-pýrasínýl-fenýlsúlfónamíð og notkun þeirra til að meðhöndla flakkboðatengda sjúkdóma | |
NO20051942D0 (no) | Substituerte 4-cindazol-3-yl)fenoler som ostrogenreseptor-(ER) ligander og deres anvendelse ved behandling av inflammatoriske sykdommer | |
DK2069342T3 (da) | Derivater af 2-aryl-6-phenyl-imidazol[1,2-A]pyridiner, fremstilling og terapeutisk anvendelse deraf | |
DK1583542T3 (da) | Sammensætninger og fremgangsmåder til antiviral kombinationsterapi | |
IS7916A (is) | Arýl alkýl karbamat afleiður framleiðslu og notkun þeirra í meðferð | |
NO20035202D0 (no) | En adenosin A2A reseptoragonist og et antikolinergmiddel i kombinasjon forbehandling av obstruktive luftveissykdommer | |
IS7699A (is) | Afleiður af díoxan-2-alkýl karbamötum, framleiðslu aðferð þeirra og notkun við meðferð sjúkdóma | |
IS8123A (is) | Ný heteróhringlaga efnasambönd sem eru gagnleg í meðhöndlun á bólgu- og ofnæmissjúkdómum; aðferðir til að framleiða þau og lyfjablöndur sem innihaldaþau | |
DE60307503D1 (de) | Antivirale nukleosidderivate | |
DK1885380T3 (da) | Natriummetaarsenit til anvendelse til behandling af metastatiske neoplastiske sygdomme | |
DK1765376T3 (da) | Topiske sammensætninger og anvendelse deraf til behandling af epitel-relaterede tilstande | |
IS8497A (is) | Aðferðir og hvarfefni til að meðhöndla bólgusjúkdóma | |
DK1487828T3 (da) | Morpholinyl-urea-derivater til anvendelse til behandling af inflammatoriske sygdomme | |
GB2429778B (en) | Method for measuring the temperature in the body of human or animal with acoustic inversion | |
DK1575951T3 (da) | Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi | |
DK1928235T3 (da) | Præparat og fremgangsmåde til anvendelse i brusk-sygdoms-tilstande | |
DK1513836T3 (da) | Piperazinylacylpiperidinderivater, fremstilling og terapeutisk anvendelse heraf | |
IS6966A (is) | Cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma |