DK162878C - Fremgangsmaade til fremstilling af en vandoploeselig fast dispersion af chlorthalidon, samt produkter indeholdende en saadan dispersion - Google Patents

Fremgangsmaade til fremstilling af en vandoploeselig fast dispersion af chlorthalidon, samt produkter indeholdende en saadan dispersion

Info

Publication number
DK162878C
DK162878C DK156784A DK156784A DK162878C DK 162878 C DK162878 C DK 162878C DK 156784 A DK156784 A DK 156784A DK 156784 A DK156784 A DK 156784A DK 162878 C DK162878 C DK 162878C
Authority
DK
Denmark
Prior art keywords
dispersion
water soluble
alkanol
chlorthalidon
preparing
Prior art date
Application number
DK156784A
Other languages
Danish (da)
English (en)
Other versions
DK156784D0 (da
DK156784A (da
DK162878B (da
Inventor
Nevedita Pandit
Stephen T Horhota
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of DK156784D0 publication Critical patent/DK156784D0/da
Publication of DK156784A publication Critical patent/DK156784A/da
Publication of DK162878B publication Critical patent/DK162878B/da
Application granted granted Critical
Publication of DK162878C publication Critical patent/DK162878C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Dental Preparations (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Indole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK156784A 1983-03-16 1984-03-15 Fremgangsmaade til fremstilling af en vandoploeselig fast dispersion af chlorthalidon, samt produkter indeholdende en saadan dispersion DK162878C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47589883A 1983-03-16 1983-03-16
US47589883 1983-03-16

Publications (4)

Publication Number Publication Date
DK156784D0 DK156784D0 (da) 1984-03-15
DK156784A DK156784A (da) 1984-09-17
DK162878B DK162878B (da) 1991-12-23
DK162878C true DK162878C (da) 1992-05-18

Family

ID=23889624

Family Applications (1)

Application Number Title Priority Date Filing Date
DK156784A DK162878C (da) 1983-03-16 1984-03-15 Fremgangsmaade til fremstilling af en vandoploeselig fast dispersion af chlorthalidon, samt produkter indeholdende en saadan dispersion

Country Status (20)

Country Link
EP (1) EP0125420B1 (de)
JP (1) JPS59176212A (de)
KR (1) KR880001755B1 (de)
AT (1) ATE31024T1 (de)
AU (1) AU562929B2 (de)
CA (1) CA1212329A (de)
DD (1) DD220225A5 (de)
DE (1) DE3467707D1 (de)
DK (1) DK162878C (de)
ES (1) ES530628A0 (de)
FI (1) FI82188C (de)
GR (1) GR81478B (de)
HU (1) HU191596B (de)
IE (1) IE57031B1 (de)
IL (1) IL71248A (de)
NO (1) NO164956C (de)
NZ (1) NZ207514A (de)
PT (1) PT78259B (de)
YU (1) YU43349B (de)
ZA (1) ZA841916B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933360A (en) * 1983-03-16 1990-06-12 Boehringer Ingelheim Pharmaceuticals, Inc. Novel chlorthalidone process and product
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
WO1988000040A1 (en) * 1986-07-02 1988-01-14 American Health Products Corporation Topical hair growing composition and kit
US5955475A (en) * 1997-06-30 1999-09-21 Endo Pharmaceuticals Inc. Process for manufacturing paroxetine solid dispersions
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3055904A (en) * 1957-11-04 1962-09-25 Geigy Chem Corp New isoindoline derivatives
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4285665A (en) * 1978-05-08 1981-08-25 Johnson, Matthey & Co., Limited Engines

Also Published As

Publication number Publication date
CA1212329A (en) 1986-10-07
IL71248A (en) 1987-02-27
IE57031B1 (en) 1992-03-25
HUT34343A (en) 1985-03-28
ATE31024T1 (de) 1987-12-15
DK156784D0 (da) 1984-03-15
FI841019A (fi) 1984-09-17
NO164956B (no) 1990-08-27
DD220225A5 (de) 1985-03-27
NO164956C (no) 1990-12-05
FI82188C (fi) 1991-02-11
ZA841916B (en) 1985-11-27
KR840007874A (ko) 1984-12-11
FI82188B (fi) 1990-10-31
NZ207514A (en) 1987-02-20
KR880001755B1 (ko) 1988-09-12
ES8602633A1 (es) 1985-12-01
EP0125420B1 (de) 1987-11-25
FI841019A0 (fi) 1984-03-14
JPS59176212A (ja) 1984-10-05
PT78259A (en) 1984-04-01
EP0125420A3 (en) 1985-03-13
AU562929B2 (en) 1987-06-25
NO841010L (no) 1984-09-17
DK156784A (da) 1984-09-17
DK162878B (da) 1991-12-23
GR81478B (de) 1984-12-11
ES530628A0 (es) 1985-12-01
PT78259B (en) 1986-08-08
YU43349B (en) 1989-06-30
EP0125420A2 (de) 1984-11-21
DE3467707D1 (en) 1988-01-07
IL71248A0 (en) 1984-06-29
IE840647L (en) 1984-09-16
HU191596B (en) 1987-03-30
AU2569684A (en) 1984-09-20
YU45884A (en) 1987-06-30

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Legal Events

Date Code Title Description
PBP Patent lapsed