DK1625403T3 - Fremgasngsmåde til forudsigelsen, diagnosen og differentialdiagnosen af Alzheimers sygdom - Google Patents

Fremgasngsmåde til forudsigelsen, diagnosen og differentialdiagnosen af Alzheimers sygdom

Info

Publication number
DK1625403T3
DK1625403T3 DK04730881T DK04730881T DK1625403T3 DK 1625403 T3 DK1625403 T3 DK 1625403T3 DK 04730881 T DK04730881 T DK 04730881T DK 04730881 T DK04730881 T DK 04730881T DK 1625403 T3 DK1625403 T3 DK 1625403T3
Authority
DK
Denmark
Prior art keywords
diagnosis
alzheimer
disease
prediction
procedure
Prior art date
Application number
DK04730881T
Other languages
Danish (da)
English (en)
Inventor
Hugo Vanderstichele
Eugeen Vanmechelen
Kaj Blennow
Meyer Geert De
Vesna Kostanjevecki
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Application granted granted Critical
Publication of DK1625403T3 publication Critical patent/DK1625403T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
DK04730881T 2003-05-22 2004-05-03 Fremgasngsmåde til forudsigelsen, diagnosen og differentialdiagnosen af Alzheimers sygdom DK1625403T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03447120A EP1480041A1 (de) 2003-05-22 2003-05-22 Verfahren zur Voraussage, zur Diagnose und zur vergleichenden Diagnose von Alzheimer
US47762103P 2003-06-11 2003-06-11
PCT/EP2004/050684 WO2004104597A1 (en) 2003-05-22 2004-05-03 Method for the prediction, diagnosis and differential diagnosis of alzheimer's disease

Publications (1)

Publication Number Publication Date
DK1625403T3 true DK1625403T3 (da) 2008-06-09

Family

ID=33041166

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04730881T DK1625403T3 (da) 2003-05-22 2004-05-03 Fremgasngsmåde til forudsigelsen, diagnosen og differentialdiagnosen af Alzheimers sygdom

Country Status (14)

Country Link
US (2) US20040265919A1 (de)
EP (2) EP1480041A1 (de)
JP (1) JP4769722B2 (de)
AT (1) ATE386942T1 (de)
AU (1) AU2004242203B2 (de)
CA (1) CA2525781C (de)
CY (1) CY1110252T1 (de)
DE (1) DE602004011931T2 (de)
DK (1) DK1625403T3 (de)
ES (1) ES2301986T3 (de)
PL (1) PL1625403T3 (de)
PT (1) PT1625403E (de)
SI (1) SI1625403T1 (de)
WO (1) WO2004104597A1 (de)

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US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
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US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
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EP1771715A4 (de) * 2004-07-19 2009-04-22 Mayo Foundation Vorhersage der alzheimerkrankheit
CA2590337C (en) 2004-12-15 2017-07-11 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
KR101439828B1 (ko) 2005-11-30 2014-09-17 애브비 인코포레이티드 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
KR20080090408A (ko) 2005-11-30 2008-10-08 아보트 러보러터리즈 항-Ａβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법
EP2361638B1 (de) 2005-12-12 2014-01-15 AC Immune S.A. A beta 1-42 spezifische monoklonale Antikörper mit therapeutischen Eigenschaften
WO2007119685A1 (ja) * 2006-04-13 2007-10-25 Sanko Junyaku Co., Ltd. β－アミロイドの血中分解速度測定によるアルツハイマー病の検定方法及び診断試薬
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
TWI551607B (zh) 2006-07-14 2016-10-01 Ａｃ免疫公司 人類化抗體
ES2535978T3 (es) * 2006-11-17 2015-05-19 Friedrich-Alexander-Universität Erlangen-Nürnberg Procedimiento para el diagnóstico diferencial de demencias
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US8895004B2 (en) 2007-02-27 2014-11-25 AbbVie Deutschland GmbH & Co. KG Method for the treatment of amyloidoses
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
SI2182983T1 (sl) 2007-07-27 2014-09-30 Janssen Alzheimer Immunotherapy Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta
PT2238166E (pt) 2007-10-05 2014-02-11 Genentech Inc Utilização do anticorpo anti-amilóide beta em doenças oculares
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
WO2009095454A2 (de) * 2008-02-01 2009-08-06 Brahms Aktiengesellschaft Verfahren zur identifizierung von therapiebedürftigen patienten mit leichten kognitiven störungen und die behandlung derartiger patienten
EP3338796A1 (de) 2008-07-21 2018-06-27 Probiodrug AG Diagnostischer antikörpertest
US20110263450A1 (en) * 2008-09-26 2011-10-27 The University Of Melbourne Alzheimer's disease biomarkers
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
WO2011033046A1 (en) * 2009-09-18 2011-03-24 Probiodrug Ag Novel assay for the detection of amyloid beta peptides
BR112012014060B8 (pt) * 2009-12-11 2021-07-27 Araclon Biotech Sl método para o diagnóstico da doença de alzheimer em um sujeito, para detecção da disfunção cognitiva branda ou para diferenciar a doença de alzheimer da disfunção cognitiva branda
DE102010014684A1 (de) * 2010-04-09 2011-10-13 Universität Duisburg-Essen Neue Ansätze zur Alzheimer-Diagnose
WO2011130377A2 (en) 2010-04-15 2011-10-20 Abbott Laboratories Amyloid-beta binding proteins
RU2607368C2 (ru) 2010-07-30 2017-01-10 Ац Иммуне С.А. Безопасные и функциональные гуманизированные антитела
CN103298833B (zh) 2010-08-14 2015-12-16 Abbvie公司 β淀粉样蛋白结合蛋白
EP2511296A1 (de) 2011-04-12 2012-10-17 Araclón Biotech, S. L. Antikörper, Kit und Verfahren zur Bestimmung von Amyloidpeptiden
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
WO2014028777A2 (en) 2012-08-16 2014-02-20 Ipierian, Inc. Methods of treating a tauopathy
US8980270B2 (en) 2013-01-18 2015-03-17 Ipierian, Inc. Methods of treating a tauopathy
US10304006B2 (en) * 2013-02-15 2019-05-28 The Charles Stark Draper Laboratory, Inc. Method for integrating and fusing heterogeneous data types to perform predictive analysis
CN105939722A (zh) 2014-02-14 2016-09-14 伊皮埃里安股份有限公司 Tau肽，抗Tau抗体，及其使用方法
US20180252665A1 (en) * 2014-05-27 2018-09-06 Case Western Reserve University System and methods for the detection of biomarkers of neurodegenerative disorders
US20170242040A1 (en) * 2014-05-30 2017-08-24 Biocross, S.L. Method for the diagnosis of alzheimer's disease and mild cognitive impairment
EP2950102A1 (de) * 2014-05-30 2015-12-02 Biocross, S.L. Verfahren zur Diagnose von Morbus Alzheimer und milder kognitiver Beeinträchtigung
CN113884683A (zh) * 2020-07-30 2022-01-04 山东京济生物工程有限公司 一种快速检测Aβ42的双抗体夹心ELISA试剂盒
US20220260559A1 (en) * 2020-11-04 2022-08-18 Seer, Inc. Biomarkers for diagnosing alzheimer's disease
EP4307988A1 (de) * 2021-03-16 2024-01-24 NeuroVision Imaging, Inc. Biofluidbasierte verfahren zur diagnose von erkrankungen im zusammenhang mit morbus alzheimer

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US5766846A (en) * 1992-07-10 1998-06-16 Athena Neurosciences Methods of screening for compounds which inhibit soluble β-amyloid peptide production
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Also Published As

Publication number Publication date
PT1625403E (pt) 2008-05-28
CY1110252T1 (el) 2015-01-14
DE602004011931D1 (de) 2008-04-03
CA2525781A1 (en) 2004-12-02
ES2301986T3 (es) 2008-07-01
EP1625403B1 (de) 2008-02-20
AU2004242203A1 (en) 2004-12-02
JP2007522434A (ja) 2007-08-09
AU2004242203B2 (en) 2008-12-11
US20080057593A1 (en) 2008-03-06
US20040265919A1 (en) 2004-12-30
PL1625403T3 (pl) 2008-10-31
ATE386942T1 (de) 2008-03-15
SI1625403T1 (sl) 2008-08-31
DE602004011931T2 (de) 2009-09-10
JP4769722B2 (ja) 2011-09-07
WO2004104597A1 (en) 2004-12-02
EP1480041A1 (de) 2004-11-24
CA2525781C (en) 2013-08-13
EP1625403A1 (de) 2006-02-15

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