DK161083C - Fremgangsmaade til fremstilling af 7-d-mandelamido-3-(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylsyremononatriumsalt - Google Patents

Fremgangsmaade til fremstilling af 7-d-mandelamido-3-(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylsyremononatriumsalt

Info

Publication number
DK161083C
DK161083C DK084885A DK84885A DK161083C DK 161083 C DK161083 C DK 161083C DK 084885 A DK084885 A DK 084885A DK 84885 A DK84885 A DK 84885A DK 161083 C DK161083 C DK 161083C
Authority
DK
Denmark
Prior art keywords
sulphomethyltetrazol
mononium
mandelamido
cephem
thiomethyl
Prior art date
Application number
DK084885A
Other languages
Danish (da)
English (en)
Other versions
DK84885D0 (da
DK84885A (da
DK161083B (da
Inventor
Theodore John Polansky
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK84885D0 publication Critical patent/DK84885D0/da
Publication of DK84885A publication Critical patent/DK84885A/da
Publication of DK161083B publication Critical patent/DK161083B/da
Application granted granted Critical
Publication of DK161083C publication Critical patent/DK161083C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK084885A 1984-02-29 1985-02-25 Fremgangsmaade til fremstilling af 7-d-mandelamido-3-(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylsyremononatriumsalt DK161083C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/584,590 US4576937A (en) 1984-02-29 1984-02-29 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
US58459084 1984-02-29

Publications (4)

Publication Number Publication Date
DK84885D0 DK84885D0 (da) 1985-02-25
DK84885A DK84885A (da) 1985-08-30
DK161083B DK161083B (da) 1991-05-27
DK161083C true DK161083C (da) 1991-11-04

Family

ID=24337979

Family Applications (1)

Application Number Title Priority Date Filing Date
DK084885A DK161083C (da) 1984-02-29 1985-02-25 Fremgangsmaade til fremstilling af 7-d-mandelamido-3-(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylsyremononatriumsalt

Country Status (25)

Country Link
US (1) US4576937A (fi)
EP (1) EP0154484B1 (fi)
JP (1) JPH0699446B2 (fi)
KR (1) KR920004821B1 (fi)
AR (1) AR246974A1 (fi)
AT (1) ATE36715T1 (fi)
AU (1) AU577571B2 (fi)
CA (1) CA1239390A (fi)
DE (1) DE3564577D1 (fi)
DK (1) DK161083C (fi)
EG (1) EG17773A (fi)
ES (1) ES8701182A1 (fi)
FI (1) FI83083C (fi)
GR (1) GR850493B (fi)
HK (1) HK78791A (fi)
HU (1) HU192330B (fi)
IE (1) IE58234B1 (fi)
IL (1) IL74455A (fi)
NO (1) NO164599C (fi)
NZ (1) NZ211233A (fi)
PH (1) PH20809A (fi)
PT (1) PT80031B (fi)
SG (1) SG67291G (fi)
ZA (1) ZA851477B (fi)
ZW (1) ZW2785A1 (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69427396T2 (de) * 1993-03-25 2002-05-23 Smithkline Beecham Corp Crystallines benzathin salz von cefonicid und verfahren zu seiner herstellung
IT1265341B1 (it) * 1993-07-16 1996-11-22 Farmabios Srl Procedimento per la preparazione di cefalosporine
US5705496A (en) * 1994-03-24 1998-01-06 Smithkline Beecham Corporation Crystalline benzathine salt of cefonicid and its preparation
GB9908776D0 (en) * 1999-04-16 1999-06-09 Smithkline Beecham Plc Formulation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119799A (en) * 1964-09-01 1968-07-10 Eastman Kodak Co Substituted mercapto-tetrazoles and their use in photographic processing methods
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
NL173169C (nl) * 1969-10-27 1983-12-16 Fujisawa Pharmaceutical Co Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking en werkwijze voor het bereiden van het daarvoor benodigde cephalosporinederivaat.
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
JPS57873B2 (fi) * 1973-12-25 1982-01-08
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
GB1509074A (en) * 1974-04-05 1978-04-26 Yamanouchi Pharma Co Ltd Cephalosporin derivatives
US4048311A (en) * 1976-01-08 1977-09-13 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins
GB1597036A (en) * 1977-03-07 1981-09-03 Lilly Co Eli Cephalosporin synthesis
EP0156771A3 (en) * 1984-03-29 1986-03-19 Biochemie Gesellschaft M.B.H. Cephalosporins

Also Published As

Publication number Publication date
JPS60202890A (ja) 1985-10-14
IL74455A0 (en) 1985-05-31
HU192330B (en) 1987-05-28
IL74455A (en) 1988-09-30
IE850491L (en) 1985-08-29
PT80031A (en) 1985-03-01
KR850006543A (ko) 1985-10-14
SG67291G (en) 1991-09-13
ES540680A0 (es) 1986-11-16
ES8701182A1 (es) 1986-11-16
PT80031B (pt) 1987-09-18
ZA851477B (en) 1985-10-30
NO164599C (no) 1990-10-24
EP0154484A3 (en) 1986-08-13
KR920004821B1 (ko) 1992-06-18
EP0154484A2 (en) 1985-09-11
IE58234B1 (en) 1993-08-11
PH20809A (en) 1987-04-21
DK84885D0 (da) 1985-02-25
NO850791L (no) 1985-08-30
EG17773A (en) 1991-06-30
US4576937A (en) 1986-03-18
GR850493B (fi) 1985-06-26
ATE36715T1 (de) 1988-09-15
FI83083B (fi) 1991-02-15
EP0154484B1 (en) 1988-08-24
JPH0699446B2 (ja) 1994-12-07
AU577571B2 (en) 1988-09-29
CA1239390A (en) 1988-07-19
NO164599B (no) 1990-07-16
FI850790A0 (fi) 1985-02-27
DE3564577D1 (de) 1988-09-29
DK84885A (da) 1985-08-30
FI850790L (fi) 1985-08-30
AU3921385A (en) 1985-09-05
DK161083B (da) 1991-05-27
FI83083C (fi) 1991-05-27
ZW2785A1 (en) 1985-05-22
AR246974A1 (es) 1994-10-31
HK78791A (en) 1991-10-11
HUT36797A (en) 1985-10-28
NZ211233A (en) 1988-06-30

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PUP Patent expired