DK1591445T3 - Fremgangsmåde til fremstilling af krystalform I af cabergolin og solvater deraf - Google Patents

Fremgangsmåde til fremstilling af krystalform I af cabergolin og solvater deraf

Info

Publication number
DK1591445T3
DK1591445T3 DK05252709T DK05252709T DK1591445T3 DK 1591445 T3 DK1591445 T3 DK 1591445T3 DK 05252709 T DK05252709 T DK 05252709T DK 05252709 T DK05252709 T DK 05252709T DK 1591445 T3 DK1591445 T3 DK 1591445T3
Authority
DK
Denmark
Prior art keywords
cabergoline
solvates
preparation
crystal form
solvate
Prior art date
Application number
DK05252709T
Other languages
Danish (da)
English (en)
Inventor
Alan Greenwood
Derek Mchattie
Parveen Bhatarah
Mark Gamble
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32482531&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1591445(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Application granted granted Critical
Publication of DK1591445T3 publication Critical patent/DK1591445T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Secondary Cells (AREA)
DK05252709T 2004-04-30 2005-04-29 Fremgangsmåde til fremstilling af krystalform I af cabergolin og solvater deraf DK1591445T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0409785.3A GB0409785D0 (en) 2004-04-30 2004-04-30 Preparation of cabergoline

Publications (1)

Publication Number Publication Date
DK1591445T3 true DK1591445T3 (da) 2008-08-11

Family

ID=32482531

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05252709T DK1591445T3 (da) 2004-04-30 2005-04-29 Fremgangsmåde til fremstilling af krystalform I af cabergolin og solvater deraf

Country Status (18)

Country Link
US (1) US7186837B2 (el)
EP (1) EP1591445B1 (el)
JP (1) JP2007535526A (el)
AT (1) ATE394397T1 (el)
AU (1) AU2005238276B2 (el)
CA (1) CA2565440C (el)
CY (1) CY1108244T1 (el)
DE (1) DE602005006465D1 (el)
DK (1) DK1591445T3 (el)
ES (1) ES2304670T3 (el)
GB (1) GB0409785D0 (el)
HR (1) HRP20080292T3 (el)
NZ (1) NZ550925A (el)
PL (1) PL1591445T3 (el)
PT (1) PT1591445E (el)
RS (1) RS50655B (el)
SI (1) SI1591445T1 (el)
WO (1) WO2005105796A1 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002319814A1 (en) 2001-08-13 2003-03-03 E.I. Du Pont De Nemours And Company Substituted 1h-dihydropyrazoles, their preparation and use
KR20060028761A (ko) * 2003-05-08 2006-04-03 아이박스 파마슈티컬스 에스.알.오. 다형의 카베르골린
GB0409785D0 (en) 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
GB0505965D0 (en) 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
EP1925616A1 (en) * 2006-10-26 2008-05-28 LEK Pharmaceuticals D.D. Process for the preparation of crystal forms of cabergoline via stable solvates of cabergoline
EP1953157A1 (en) 2007-01-31 2008-08-06 LEK Pharmaceuticals D.D. New crystal form of cabergoline

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535235A (de) 1970-06-19 1973-03-31 Sandoz Ag Verfahren zur Herstellung neuer reaktionsträger Lysergsäurederivate
CH535236A (de) 1970-06-19 1973-03-31 Sandoz Ag Verfahren zur Herstellung neuer reaktionsträger Lysergsäurederivate
US3920664A (en) 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
PH11140A (en) 1973-11-28 1977-10-27 Lilly Co Eli D-6-alkyl-2,8-disubstituted ergolines and a process for inhibiting the secretion of prolactin in mammals
CH587858A5 (el) 1973-11-28 1977-05-13 Sandoz Ag
DE2525962A1 (de) 1974-06-21 1976-01-08 Sandoz Ag Neue heterocyclische verbindungen, ihre herstellung und verwendung
US4180582A (en) 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4166182A (en) 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
NL189462C (nl) 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4526892A (en) 1981-03-03 1985-07-02 Farmitalia Carlo Erba, S.P.A. Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas
FI76085C (fi) 1981-07-21 1988-09-09 Erba Farmitalia Foerfarande foer framstaellning av ergolinderivat.
GB2103603B (en) 1981-08-11 1985-04-11 Erba Farmitalia Ergoline derivatives
US4782152A (en) 1985-08-16 1988-11-01 Eli Lilly And Company Decyanation of pergolide intermediate
GB9205439D0 (en) 1992-03-12 1992-04-22 Erba Carlo Spa Process for the synthesis of ergoline derivatives
CZ287176B6 (cs) 1997-10-03 2000-10-11 Galena A. S. Způsob přípravy ergolinových derivátů
IT1307934B1 (it) 1999-01-27 2001-11-29 Poli Ind Chimica Spa Processo per la preparazione di derivati alchimercaptometilergolinici.
GB0007307D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Crystalline form || of cabergoline
GB0007309D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Crystalline form V|| of cabergoline
GB0007308D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Process for preparing crystalline form | of cabergoline
CA2478149A1 (en) 2002-03-15 2003-09-25 Pharmacia Corporation Process for preparing crystalline form i of cabergoline
AU2003218753A1 (en) 2002-03-15 2003-09-29 Pharmacia Corporation Process for preparing crystalline form i of cabergoline
KR20060028761A (ko) 2003-05-08 2006-04-03 아이박스 파마슈티컬스 에스.알.오. 다형의 카베르골린
GB0409785D0 (en) 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline

Also Published As

Publication number Publication date
JP2007535526A (ja) 2007-12-06
ATE394397T1 (de) 2008-05-15
US20050245560A1 (en) 2005-11-03
GB0409785D0 (en) 2004-06-09
WO2005105796A1 (en) 2005-11-10
CA2565440C (en) 2011-09-20
PL1591445T3 (pl) 2008-09-30
AU2005238276B2 (en) 2011-08-18
ES2304670T3 (es) 2008-10-16
US7186837B2 (en) 2007-03-06
EP1591445A1 (en) 2005-11-02
CA2565440A1 (en) 2005-11-10
NZ550925A (en) 2010-02-26
EP1591445B1 (en) 2008-05-07
RS50655B (sr) 2010-06-30
AU2005238276A1 (en) 2005-11-10
CY1108244T1 (el) 2014-02-12
PT1591445E (pt) 2008-06-02
SI1591445T1 (sl) 2008-08-31
HRP20080292T3 (en) 2008-07-31
DE602005006465D1 (de) 2008-06-19

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