DK157891C - Fremgangsmaade til fremstilling af 11beta,21-dihydroxy-2'-methyl-5'-betah-1,4-pregnadieno(16,17-d)-oxazol-3,20-dion - Google Patents

Fremgangsmaade til fremstilling af 11beta,21-dihydroxy-2'-methyl-5'-betah-1,4-pregnadieno(16,17-d)-oxazol-3,20-dion

Info

Publication number
DK157891C
DK157891C DK572081A DK572081A DK157891C DK 157891 C DK157891 C DK 157891C DK 572081 A DK572081 A DK 572081A DK 572081 A DK572081 A DK 572081A DK 157891 C DK157891 C DK 157891C
Authority
DK
Denmark
Prior art keywords
oxazole
dihydroxy
methyl
pregnadieno
preparing
Prior art date
Application number
DK572081A
Other languages
English (en)
Other versions
DK572081A (da
DK157891B (da
Inventor
Alfred Weber
Mario Kennecke
Rudolf Mueller
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK572081A publication Critical patent/DK572081A/da
Publication of DK157891B publication Critical patent/DK157891B/da
Application granted granted Critical
Publication of DK157891C publication Critical patent/DK157891C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/02—Dehydrogenating; Dehydroxylating
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK572081A 1980-12-23 1981-12-22 Fremgangsmaade til fremstilling af 11beta,21-dihydroxy-2'-methyl-5'-betah-1,4-pregnadieno(16,17-d)-oxazol-3,20-dion DK157891C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3049401 1980-12-23
DE3049401 1980-12-23

Publications (3)

Publication Number Publication Date
DK572081A DK572081A (da) 1982-06-24
DK157891B DK157891B (da) 1990-02-26
DK157891C true DK157891C (da) 1990-09-03

Family

ID=6120492

Family Applications (1)

Application Number Title Priority Date Filing Date
DK572081A DK157891C (da) 1980-12-23 1981-12-22 Fremgangsmaade til fremstilling af 11beta,21-dihydroxy-2'-methyl-5'-betah-1,4-pregnadieno(16,17-d)-oxazol-3,20-dion

Country Status (10)

Country Link
US (1) US4431732A (da)
EP (1) EP0055832B1 (da)
JP (1) JPS57170197A (da)
AT (1) ATE18257T1 (da)
DD (1) DD202050A5 (da)
DE (1) DE3173923D1 (da)
DK (1) DK157891C (da)
FI (1) FI72144C (da)
HU (1) HU186454B (da)
RO (1) RO83630B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE21119T1 (de) * 1980-12-23 1986-08-15 Schering Ag Verfahren zur herstellung von 3-oxo-delta-1,4steroiden.
JPS6145294A (ja) * 1984-08-09 1986-03-05 ヤマハ株式会社 楽音合成方法
JPH0799478B2 (ja) * 1985-11-22 1995-10-25 カシオ計算機株式会社 電子楽器
GB8730216D0 (en) * 1987-12-29 1988-02-03 Lepetit Spa Process for preparation of pregnenooxazolines
CN101177443B (zh) * 2006-11-09 2011-08-03 天津药业研究院有限公司 新的甾体化合物及其应用
CN110157764B (zh) * 2019-05-29 2021-01-29 浙江仙琚制药股份有限公司 一种地塞米松中间体的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070176B (de) * 1959-12-03 American Cyanamid Company, New York, N. Y. (V. St. A.) Verfahren zur Herstellung neuer Steroidverbindungen der 1, 4 - Pregnadienreihe
US2837464A (en) * 1955-01-11 1958-06-03 Schering Corp Process for production of dienes by corynebacteria
DE1093792B (de) * 1957-11-27 1960-12-01 Pfizer & Co C Verfahren zur Herstellung von 3-Keto-í¸-steroiden
US2981659A (en) * 1959-05-01 1961-04-25 Upjohn Co Method for the microbiological conversion of pregnane series steroids
DE1107225B (de) * 1959-08-05 1961-05-25 Hoechst Ag Verfahren zur Herstellung von 1, 4, 17(20)-Pregnatrienen
US3274182A (en) * 1963-12-28 1966-09-20 Searle & Co Process for reducing 19-methyl-1, 4-dien-3-ones to corresponding 19-nor-3-oxy-1, 3, 5(10)-trienes
NL6705450A (da) * 1965-10-22 1968-10-21
NL6703781A (da) * 1967-03-13 1968-09-16
US3718673A (en) * 1971-02-01 1973-02-27 Du Pont Process for the preparation of 21-chloro-6,6,9alpha-trifluoro-11beta, alpha, 17alpha-trihydroxy-1,4-pregnadien-3,20-dione 16,17-ketals and selected intermediates
US4101378A (en) * 1975-06-06 1978-07-18 Mitsubishi Chemical Industries Limited Process for the microbiological oxidation of steroids
US4246346A (en) * 1978-09-05 1981-01-20 Aktiebolaget Fermenta Antibiotic and steroid transformation process

Also Published As

Publication number Publication date
EP0055832A1 (de) 1982-07-14
US4431732A (en) 1984-02-14
JPS57170197A (en) 1982-10-20
DK572081A (da) 1982-06-24
EP0055832B1 (de) 1986-02-26
FI72144C (fi) 1987-04-13
DD202050A5 (de) 1983-08-24
ATE18257T1 (de) 1986-03-15
FI72144B (fi) 1986-12-31
DK157891B (da) 1990-02-26
HU186454B (en) 1985-08-28
DE3173923D1 (en) 1986-04-03
FI814127L (fi) 1982-06-24
JPH0218071B2 (da) 1990-04-24
RO83630A (ro) 1984-06-21
RO83630B (ro) 1984-08-30

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