DK157082C - Fremgangsmaade til fremstilling af adriamycin og halogenidsalte deraf - Google Patents

Fremgangsmaade til fremstilling af adriamycin og halogenidsalte deraf

Info

Publication number
DK157082C
DK157082C DK059486A DK59486A DK157082C DK 157082 C DK157082 C DK 157082C DK 059486 A DK059486 A DK 059486A DK 59486 A DK59486 A DK 59486A DK 157082 C DK157082 C DK 157082C
Authority
DK
Denmark
Prior art keywords
halogeneal
adriamycine
salts
procedure
preparation
Prior art date
Application number
DK059486A
Other languages
English (en)
Other versions
DK157082B (da
DK59486D0 (da
DK59486A (da
Inventor
Janos Balint
Szabolcs Borbely
Zsuzsanna Emri
Jozsef Fazekas
Gyoergy Toth
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of DK59486D0 publication Critical patent/DK59486D0/da
Publication of DK59486A publication Critical patent/DK59486A/da
Publication of DK157082B publication Critical patent/DK157082B/da
Application granted granted Critical
Publication of DK157082C publication Critical patent/DK157082C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK059486A 1984-06-14 1986-02-06 Fremgangsmaade til fremstilling af adriamycin og halogenidsalte deraf DK157082C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU8400037 1984-06-14
PCT/HU1984/000037 WO1986000073A1 (en) 1984-06-14 1984-06-14 Process for preparing adriamycine and halide salts thereof

Publications (4)

Publication Number Publication Date
DK59486D0 DK59486D0 (da) 1986-02-06
DK59486A DK59486A (da) 1986-02-06
DK157082B DK157082B (da) 1989-11-06
DK157082C true DK157082C (da) 1990-04-09

Family

ID=10980572

Family Applications (1)

Application Number Title Priority Date Filing Date
DK059486A DK157082C (da) 1984-06-14 1986-02-06 Fremgangsmaade til fremstilling af adriamycin og halogenidsalte deraf

Country Status (5)

Country Link
EP (1) EP0183691A1 (da)
JP (1) JPS61502956A (da)
DK (1) DK157082C (da)
FI (1) FI860683A (da)
WO (1) WO1986000073A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026691A (en) * 1987-03-30 1991-06-25 The Upjohn Company Combination of minoxidil and an antiinflammatory agent for treating patterned alopecia
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
IT1230505B (it) * 1988-10-11 1991-10-25 Sicor Spa Procedimento per la conversione della daunorubicina in doxorubicina.
ATE195526T1 (de) 1996-12-16 2000-09-15 Pharmachemie Bv Verfahren zur herstellung von epirubicin oder zusatzsalzen davon, von daunorubicin
US7388083B2 (en) 2005-03-07 2008-06-17 Solux Corporation Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
EP1976858B1 (en) 2005-12-13 2016-01-06 Solux Corporation Method for preparing 4-demethyldaunorubicin
US8802830B2 (en) 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
IT1398273B1 (it) * 2009-05-08 2013-02-22 Antibioticos Spa Procedimento per la preparazione di 14-bromo daunomicina
IT1397234B1 (it) * 2010-01-08 2013-01-04 Antibioticos Spa Processo per la preparazione di doxorubicina.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL145536B (nl) * 1968-04-12 1975-04-15 Farmaceutici Italia Werkwijze voor de bereiding van een nieuw antibioticum of zijn aglycon.
GB1511680A (en) * 1975-11-18 1978-05-24 Farmaceutici Italia Daunosaminyl anthracyclinones
AT358736B (de) * 1976-12-22 1980-09-25 Erba Farmitalia Verfahren zur herstellung von neuen antitumorglycosiden
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative

Also Published As

Publication number Publication date
DK157082B (da) 1989-11-06
JPS61502956A (ja) 1986-12-18
FI860683A0 (fi) 1986-02-14
DK59486D0 (da) 1986-02-06
WO1986000073A1 (en) 1986-01-03
FI860683A (fi) 1986-02-14
DK59486A (da) 1986-02-06
EP0183691A1 (en) 1986-06-11

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Legal Events

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PBP Patent lapsed