DK153485A - Fremgangsmaade til fremstilling af aryl-substituerede pyrido(1,4)benzodiazepiner samt mellemprodukter hertil og deres fremstilling - Google Patents

Fremgangsmaade til fremstilling af aryl-substituerede pyrido(1,4)benzodiazepiner samt mellemprodukter hertil og deres fremstilling Download PDF

Info

Publication number
DK153485A
DK153485A DK153485A DK153485A DK153485A DK 153485 A DK153485 A DK 153485A DK 153485 A DK153485 A DK 153485A DK 153485 A DK153485 A DK 153485A DK 153485 A DK153485 A DK 153485A
Authority
DK
Denmark
Prior art keywords
preparation
benzodiazepines
intermediates
aryl
procedure
Prior art date
Application number
DK153485A
Other languages
English (en)
Other versions
DK153485D0 (da
Inventor
Young Sek Lo
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK153485D0 publication Critical patent/DK153485D0/da
Publication of DK153485A publication Critical patent/DK153485A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
DK153485A 1984-04-06 1985-04-03 Fremgangsmaade til fremstilling af aryl-substituerede pyrido(1,4)benzodiazepiner samt mellemprodukter hertil og deres fremstilling DK153485A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/597,413 US4560510A (en) 1984-04-06 1984-04-06 Process and intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines

Publications (2)

Publication Number Publication Date
DK153485D0 DK153485D0 (da) 1985-04-03
DK153485A true DK153485A (da) 1985-10-07

Family

ID=24391395

Family Applications (1)

Application Number Title Priority Date Filing Date
DK153485A DK153485A (da) 1984-04-06 1985-04-03 Fremgangsmaade til fremstilling af aryl-substituerede pyrido(1,4)benzodiazepiner samt mellemprodukter hertil og deres fremstilling

Country Status (20)

Country Link
US (1) US4560510A (da)
EP (1) EP0157656A3 (da)
JP (1) JPS60218390A (da)
KR (1) KR900004146B1 (da)
AU (2) AU572967B2 (da)
CA (1) CA1255301A (da)
DK (1) DK153485A (da)
ES (4) ES8801260A1 (da)
FI (1) FI851388L (da)
GR (1) GR850826B (da)
HU (1) HU195811B (da)
IL (1) IL74141A (da)
IN (1) IN160899B (da)
NO (1) NO164238C (da)
NZ (1) NZ211701A (da)
PH (1) PH21971A (da)
PL (1) PL146369B1 (da)
PT (1) PT80245B (da)
YU (1) YU46785A (da)
ZA (1) ZA85591B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749788A (en) * 1987-04-13 1988-06-07 A. H. Robins Company, Incorporated Process for the preparation of aryl-pyrido(1,4) benzodiazepines
US5009699A (en) * 1990-06-22 1991-04-23 American Cyanamid Company 1-{[O-(cyclopropylcarbonyl)phenyl]sulfamoyl}-3-(4,6-dimethoxy-2-pyrimidinyl)urea herbicidal composition and use
US5602113A (en) * 1991-02-07 1997-02-11 Boehringer Ingelheim Pharmaceuticals, Inc. Pyridobenzo- and pyridiothieno-diazepines useful for the treatment of HIV infection
US5686445A (en) * 1993-07-29 1997-11-11 American Cyanamid Company Pyridobenzoxazepine and pyridobenzothiazepine vasopressin antagonists
US6288057B1 (en) * 1994-08-31 2001-09-11 Eli Lilly And Company Physical form of dihydro-2,3-benzodiazepine derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431304A (en) * 1965-09-22 1969-03-04 Hoffmann La Roche 2 - aminoalkylamino-benzophenones-oximes and imines and the salts thereof
DE3222809A1 (de) * 1981-07-15 1983-02-03 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur herstellung von 5,11-dihydro-6h-pyrido(2,3-b)-(1,4) benzodiazepin-6-onen
US4447361A (en) * 1981-09-24 1984-05-08 A. H. Robins Company, Inc. Aryl substituted pyrido[1,4]benzodiazepines
EP0076017B1 (en) * 1981-09-24 1990-08-16 A.H. Robins Company, Incorporated Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor
US4480100A (en) * 1982-09-30 1984-10-30 A. H. Robins Company, Inc. [2-[(Nitropyridinyl)amino]phenyl]arymethanones

Also Published As

Publication number Publication date
AU3948285A (en) 1985-10-10
AU601260B2 (en) 1990-09-06
ZA85591B (en) 1985-09-25
PT80245B (en) 1986-11-20
PT80245A (en) 1985-05-01
NO851351L (no) 1985-10-07
KR850007598A (ko) 1985-12-07
NZ211701A (en) 1990-04-26
CA1262353C (da) 1989-10-17
AU572967B2 (en) 1988-05-19
ES553983A0 (es) 1987-04-16
US4560510A (en) 1985-12-24
JPS60218390A (ja) 1985-11-01
EP0157656A2 (en) 1985-10-09
IL74141A (en) 1989-09-10
IN160899B (da) 1987-08-15
ES8604153A1 (es) 1986-01-16
HU195811B (en) 1988-07-28
FI851388A0 (fi) 1985-04-04
YU46785A (en) 1988-04-30
ES545130A0 (es) 1986-01-16
NO164238C (no) 1990-09-12
AU1171088A (en) 1988-05-26
NO164238B (no) 1990-06-05
KR900004146B1 (ko) 1990-06-16
DK153485D0 (da) 1985-04-03
PH21971A (en) 1988-05-02
ES8801260A1 (es) 1986-11-16
ES545129A0 (es) 1986-01-16
EP0157656A3 (en) 1987-07-15
FI851388L (fi) 1985-10-07
PL252809A1 (en) 1986-08-26
ES8604169A1 (es) 1986-01-16
ES540923A0 (es) 1986-11-16
IL74141A0 (en) 1985-04-30
PL146369B1 (en) 1989-01-31
HUT38934A (en) 1986-07-28
GR850826B (da) 1985-11-25
ES8802303A1 (es) 1987-04-16
CA1255301A (en) 1989-06-06

Similar Documents

Publication Publication Date Title
FI870439A (fi) Apparat foer framstaellning av kapslar med flera kamrar.
DK119086D0 (da) Fremgangsmaade til fremstilling af oligonucleotider
DK382785D0 (da) Alfa-(o-chlorphenyl)-aminomethylen-beta-formylaminopropionitril, fremgangsmaade til fremstilling af dette samt anvendelse af dette til fremstilling af 2-methyl-4-amino-5-formylaminomethyl-pyrimidin
FI864891A (fi) Foerfarande foer framstaellning av 6,7,8,9-tetrahydro-10-metylpyrido/1,2-a/indol-9-aminer och deras derivat.
DK52986A (da) Fremgangsmaade til fremstilling af antibiotikum l 17392 (deglucoteicoplanin)
DK38493A (da) Fremgangsmaade til fremstilling af alkoxymethylether- og alkoxymethylesterderivater af glyceroler
DK153485D0 (da) Fremgangsmaade til fremstilling af aryl-substituerede pyrido(1,4)benzodiazepiner samt mellemprodukter hertil og deres fremstilling
DK296485A (da) Fremgangsmaade til fremstilling af l-phenylalanin
DK434685D0 (da) Fremgangsmaade til fremstilling af hidtil ukendte hydroxythioalkener samt de herved fremstillede forbindelser
DK34185D0 (da) 1,4-benzoquinon-derivater og benzen-derivater samt fremgangsmaade til fremstilling af saadanne derivater
DK239485D0 (da) Krystallinsk ferrophosphoaluminat samt fremgangsmaade til fremstilling og anvendelse af dette
DK258886A (da) Fremgangsmaade til fremstilling af alkyloxiraner
ES541910A0 (es) Procedimiento para la fabricacion de derivados de 4,7-dihi- dropirazolo (3,4-b)piridina
DK79685D0 (da) Fremgangsmaade til fremstilling af riboflavin
DK509986D0 (da) Fremgangsmaade til fremstilling af aryl-cyanamider
DK98386A (da) Fremgangsmaade og mellemprodukter til fremstilling af 4-alkoxy-6-alkyl-2-cyanamino-1,3,5-triaziner samt mellemprodukternes fremstilling
DK296986D0 (da) Fremgangsmaade til fremstilling af 3,5-dichlor-2-pyridon
DK98086D0 (da) Fremgangsmaade og mellemprodukter til fremstilling af 2-cyanamino-1,3,5-triaziner samt mellemprodukternes fremstilling
DK564985D0 (da) Fremgangsmaade til fremstilling af alkylthioacetamidiner
DK163830C (da) Fremgangsmaade til fremstilling af riboflavin
DK291785A (da) Fremgangsmaade til fremstilling af iminderivater
NO850189L (no) Fremgangsmaate for fremstilling av cyanetylerte benzodiazepiner
DK308884D0 (da) Alfa-galactosidase, fremgangsmaade til udvaelgelse af en alfa-galactosidase-producerende mikroorganisme, fremgangsmaade til fremstilling af alfa-galactosidase og anvendelse deraf
DK64085D0 (da) Fremgangsmaade til fremstilling af imidazolderivater
DK390887A (da) Fremgangsmaade til fremstilling af 7alfa-acetylthiosteroider

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
PBP Patent lapsed