CA1262353C - - Google Patents

Info

Publication number
CA1262353C
CA1262353C CA 478110 CA478110A CA1262353C CA 1262353 C CA1262353 C CA 1262353C CA 478110 CA478110 CA 478110 CA 478110 A CA478110 A CA 478110A CA 1262353 C CA1262353 C CA 1262353C
Authority
CA
Canada
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 478110
Other versions
CA1255301A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000574154A priority Critical patent/CA1262353A/en
Application granted granted Critical
Publication of CA1255301A publication Critical patent/CA1255301A/en
Publication of CA1262353C publication Critical patent/CA1262353C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
CA000478110A 1984-04-06 1985-04-02 METHOD AND INTERMEDIATE PRODUCTS FOR THE PREPARATION OF ARYL SUBSTITUTION DERIVATIVES OF PYRIDO[1,4]BENZODIAZEPINES Expired CA1255301A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000574154A CA1262353A (en) 1984-04-06 1988-08-08 Aromatic ketone derivative intermediates for the preparation of antidepressant pyrido [1,4] benzodiazepines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/597,413 US4560510A (en) 1984-04-06 1984-04-06 Process and intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000574154A Division CA1262353A (en) 1984-04-06 1988-08-08 Aromatic ketone derivative intermediates for the preparation of antidepressant pyrido [1,4] benzodiazepines

Publications (2)

Publication Number Publication Date
CA1255301A CA1255301A (en) 1989-06-06
CA1262353C true CA1262353C (da) 1989-10-17

Family

ID=24391395

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000478110A Expired CA1255301A (en) 1984-04-06 1985-04-02 METHOD AND INTERMEDIATE PRODUCTS FOR THE PREPARATION OF ARYL SUBSTITUTION DERIVATIVES OF PYRIDO[1,4]BENZODIAZEPINES

Country Status (20)

Country Link
US (1) US4560510A (da)
EP (1) EP0157656A3 (da)
JP (1) JPS60218390A (da)
KR (1) KR900004146B1 (da)
AU (2) AU572967B2 (da)
CA (1) CA1255301A (da)
DK (1) DK153485A (da)
ES (4) ES8801260A1 (da)
FI (1) FI851388L (da)
GR (1) GR850826B (da)
HU (1) HU195811B (da)
IL (1) IL74141A (da)
IN (1) IN160899B (da)
NO (1) NO164238C (da)
NZ (1) NZ211701A (da)
PH (1) PH21971A (da)
PL (1) PL146369B1 (da)
PT (1) PT80245B (da)
YU (1) YU46785A (da)
ZA (1) ZA85591B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749788A (en) * 1987-04-13 1988-06-07 A. H. Robins Company, Incorporated Process for the preparation of aryl-pyrido(1,4) benzodiazepines
US5009699A (en) * 1990-06-22 1991-04-23 American Cyanamid Company 1-{[O-(cyclopropylcarbonyl)phenyl]sulfamoyl}-3-(4,6-dimethoxy-2-pyrimidinyl)urea herbicidal composition and use
US5602113A (en) * 1991-02-07 1997-02-11 Boehringer Ingelheim Pharmaceuticals, Inc. Pyridobenzo- and pyridiothieno-diazepines useful for the treatment of HIV infection
US5686445A (en) * 1993-07-29 1997-11-11 American Cyanamid Company Pyridobenzoxazepine and pyridobenzothiazepine vasopressin antagonists
US6288057B1 (en) * 1994-08-31 2001-09-11 Eli Lilly And Company Physical form of dihydro-2,3-benzodiazepine derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431304A (en) * 1965-09-22 1969-03-04 Hoffmann La Roche 2 - aminoalkylamino-benzophenones-oximes and imines and the salts thereof
DE3222809A1 (de) * 1981-07-15 1983-02-03 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur herstellung von 5,11-dihydro-6h-pyrido(2,3-b)-(1,4) benzodiazepin-6-onen
US4447361A (en) * 1981-09-24 1984-05-08 A. H. Robins Company, Inc. Aryl substituted pyrido[1,4]benzodiazepines
EP0076017B1 (en) * 1981-09-24 1990-08-16 A.H. Robins Company, Incorporated Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor
US4480100A (en) * 1982-09-30 1984-10-30 A. H. Robins Company, Inc. [2-[(Nitropyridinyl)amino]phenyl]arymethanones

Also Published As

Publication number Publication date
AU3948285A (en) 1985-10-10
AU601260B2 (en) 1990-09-06
ZA85591B (en) 1985-09-25
PT80245B (en) 1986-11-20
PT80245A (en) 1985-05-01
NO851351L (no) 1985-10-07
KR850007598A (ko) 1985-12-07
NZ211701A (en) 1990-04-26
DK153485A (da) 1985-10-07
AU572967B2 (en) 1988-05-19
ES553983A0 (es) 1987-04-16
US4560510A (en) 1985-12-24
JPS60218390A (ja) 1985-11-01
EP0157656A2 (en) 1985-10-09
IL74141A (en) 1989-09-10
IN160899B (da) 1987-08-15
ES8604153A1 (es) 1986-01-16
HU195811B (en) 1988-07-28
FI851388A0 (fi) 1985-04-04
YU46785A (en) 1988-04-30
ES545130A0 (es) 1986-01-16
NO164238C (no) 1990-09-12
AU1171088A (en) 1988-05-26
NO164238B (no) 1990-06-05
KR900004146B1 (ko) 1990-06-16
DK153485D0 (da) 1985-04-03
PH21971A (en) 1988-05-02
ES8801260A1 (es) 1986-11-16
ES545129A0 (es) 1986-01-16
EP0157656A3 (en) 1987-07-15
FI851388L (fi) 1985-10-07
PL252809A1 (en) 1986-08-26
ES8604169A1 (es) 1986-01-16
ES540923A0 (es) 1986-11-16
IL74141A0 (en) 1985-04-30
PL146369B1 (en) 1989-01-31
HUT38934A (en) 1986-07-28
GR850826B (da) 1985-11-25
ES8802303A1 (es) 1987-04-16
CA1255301A (en) 1989-06-06

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Legal Events

Date Code Title Description
MKEX Expiry