DK1523678T3 - Funktionelle screeningsmetoder involverende protein-translokation/redistribution - Google Patents

Funktionelle screeningsmetoder involverende protein-translokation/redistribution

Info

Publication number
DK1523678T3
DK1523678T3 DK03765149T DK03765149T DK1523678T3 DK 1523678 T3 DK1523678 T3 DK 1523678T3 DK 03765149 T DK03765149 T DK 03765149T DK 03765149 T DK03765149 T DK 03765149T DK 1523678 T3 DK1523678 T3 DK 1523678T3
Authority
DK
Denmark
Prior art keywords
redistribution
screening methods
methods involving
functional screening
protein translocation
Prior art date
Application number
DK03765149T
Other languages
Danish (da)
English (en)
Inventor
Gerard O'beirne
Nicholas Thomas
Original Assignee
Ge Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Uk Ltd filed Critical Ge Healthcare Uk Ltd
Application granted granted Critical
Publication of DK1523678T3 publication Critical patent/DK1523678T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
DK03765149T 2002-07-18 2003-07-10 Funktionelle screeningsmetoder involverende protein-translokation/redistribution DK1523678T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216674.2A GB0216674D0 (en) 2002-07-18 2002-07-18 Functional screening method
PCT/GB2003/002983 WO2004009847A2 (fr) 2002-07-18 2003-07-10 Procede de criblage fonctionnel

Publications (1)

Publication Number Publication Date
DK1523678T3 true DK1523678T3 (da) 2009-02-02

Family

ID=9940685

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03765149T DK1523678T3 (da) 2002-07-18 2003-07-10 Funktionelle screeningsmetoder involverende protein-translokation/redistribution

Country Status (12)

Country Link
US (1) US20050272035A1 (fr)
EP (1) EP1523678B1 (fr)
JP (1) JP4532270B2 (fr)
AT (1) ATE410681T1 (fr)
AU (1) AU2003254442B2 (fr)
CA (1) CA2493409C (fr)
DE (1) DE60323983D1 (fr)
DK (1) DK1523678T3 (fr)
ES (1) ES2314249T3 (fr)
GB (1) GB0216674D0 (fr)
IL (1) IL166238A0 (fr)
WO (1) WO2004009847A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101147147B1 (ko) 2004-04-01 2012-05-25 머크 샤프 앤드 돔 코포레이션 Rna 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
GB0410105D0 (en) * 2004-05-06 2004-06-09 Amersham Biosciences Uk Ltd Method for characterising compounds
US7923207B2 (en) * 2004-11-22 2011-04-12 Dharmacon, Inc. Apparatus and system having dry gene silencing pools
JP5352462B2 (ja) 2006-09-22 2013-11-27 ダーマコン, インコーポレイテッド 二本鎖オリゴヌクレオチド複合体、rna干渉による遺伝子サイレンシング方法、および医薬品組成物
GB0624462D0 (en) * 2006-12-07 2007-01-17 Ge Healthcare Ltd Method for determining gentoxicity
US8188060B2 (en) 2008-02-11 2012-05-29 Dharmacon, Inc. Duplex oligonucleotides with enhanced functionality in gene regulation
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
EP3172562B1 (fr) * 2014-07-21 2019-03-13 Novellusdx Ltd. Procédés et systèmes pour déterminer un indice oncogénique de mutations spécifiques d'un patient
CN111500545A (zh) * 2020-04-30 2020-08-07 中国农业科学院农业质量标准与检测技术研究所 基于转基因工程细胞株测定糖皮质激素类混合物的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0986753T4 (da) * 1997-04-07 2005-12-19 Bioimage As Fremgangsmåde til uddragning af kvantitativ information, hvad angår en påvirkning af et cellulært respons
US6383758B1 (en) * 1998-01-09 2002-05-07 The Governing Council Of The University Of Toronto Alzheimer's related proteins and methods of use
WO2000020859A1 (fr) * 1998-10-05 2000-04-13 Duke University METHODE ET APPAREIL DE DETECTION D'INTERACTIONS DE LIAISON $i(IN VIVO)
WO2000068661A2 (fr) * 1999-05-12 2000-11-16 Gordon Adrienne S Detection de l'exposition cellulaire aux drogues engendrant la dependance

Also Published As

Publication number Publication date
WO2004009847A2 (fr) 2004-01-29
JP4532270B2 (ja) 2010-08-25
DE60323983D1 (de) 2008-11-20
CA2493409C (fr) 2009-06-09
ES2314249T3 (es) 2009-03-16
EP1523678A2 (fr) 2005-04-20
US20050272035A1 (en) 2005-12-08
CA2493409A1 (fr) 2004-01-29
IL166238A0 (en) 2006-01-15
EP1523678B1 (fr) 2008-10-08
WO2004009847A3 (fr) 2004-04-15
ATE410681T1 (de) 2008-10-15
JP2005532817A (ja) 2005-11-04
AU2003254442B2 (en) 2006-11-02
GB0216674D0 (en) 2002-08-28
AU2003254442A1 (en) 2004-02-09

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