DK149457C - Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf - Google Patents

Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf

Info

Publication number
DK149457C
DK149457C DK213983A DK213983A DK149457C DK 149457 C DK149457 C DK 149457C DK 213983 A DK213983 A DK 213983A DK 213983 A DK213983 A DK 213983A DK 149457 C DK149457 C DK 149457C
Authority
DK
Denmark
Prior art keywords
esters
procedure
human insulin
preparing human
preparing
Prior art date
Application number
DK213983A
Other languages
Danish (da)
English (en)
Other versions
DK213983A (da
DK213983D0 (da
DK149457B (da
Inventor
Finn Hede Andresen
Per Balschmidt
Kim Ry Hejnaes
Hans Kofod
Original Assignee
Novo Nordisk Fonden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Fonden filed Critical Novo Nordisk Fonden
Publication of DK213983A publication Critical patent/DK213983A/da
Publication of DK213983D0 publication Critical patent/DK213983D0/da
Publication of DK149457B publication Critical patent/DK149457B/da
Application granted granted Critical
Publication of DK149457C publication Critical patent/DK149457C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DK213983A 1982-06-07 1983-05-13 Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf DK149457C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK254682 1982-06-07
DK254682 1982-06-07
DK254582 1982-06-07
DK254582 1982-06-07
DK8200082 1982-09-14
PCT/DK1982/000082 WO1983001074A1 (en) 1981-09-15 1982-09-14 Enzymatic preparation of human insulin or b-30 esters thereof

Publications (4)

Publication Number Publication Date
DK213983A DK213983A (da) 1983-05-13
DK213983D0 DK213983D0 (da) 1983-05-13
DK149457B DK149457B (da) 1986-06-16
DK149457C true DK149457C (da) 1991-11-25

Family

ID=26066590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK213983A DK149457C (da) 1982-06-07 1983-05-13 Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf

Country Status (11)

Country Link
US (1) US4601979A (no)
EP (1) EP0088117B1 (no)
JP (1) JPS58501455A (no)
AU (1) AU551174B2 (no)
CA (1) CA1174623A (no)
DK (1) DK149457C (no)
ES (1) ES515713A0 (no)
FI (1) FI78119C (no)
IT (1) IT1189353B (no)
NO (1) NO156052C (no)
WO (1) WO1983001074A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0367302A3 (en) * 1982-04-23 1991-06-19 Wako Pure Chemical Industries, Ltd. Process for semi-synthesis of human insulin, water-soluble cross-linked achromobacter protease i for use therein and a process for preparing the same
EP0294851A3 (de) * 1987-06-12 1990-05-09 Berlin-Chemie Ag Verfahren zur Herstellung von Humaninsulin und seinen Derivaten
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
CA2306905A1 (en) 1997-10-24 1999-05-06 Eli Lilly And Company Fatty acid-acylated insulin analogs
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
RU2376379C2 (ru) 2001-11-19 2009-12-20 Ново Нордиск А/С Способ получения инсулиновых соединений
US8173840B2 (en) * 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
US7589233B2 (en) * 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
US10611813B2 (en) * 2013-12-23 2020-04-07 Biocon Research Limited Method of production of human insulin methyl ester

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
AU545416B2 (en) * 1979-04-06 1985-07-11 Carlsberg Biotechnology Ltd. A/S A process for enzymatic production of peptides
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
JPS55138392A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DE3064479D1 (en) * 1979-04-13 1983-09-08 Shionogi & Co Process for preparing a b30-threonine insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
FI78119B (fi) 1989-02-28
EP0088117B1 (en) 1986-09-24
FI831157A0 (fi) 1983-04-06
AU8953982A (en) 1983-04-08
FI831157L (fi) 1983-04-06
FI78119C (fi) 1989-06-12
AU551174B2 (en) 1986-04-17
DK213983A (da) 1983-05-13
NO831730L (no) 1983-05-13
IT1189353B (it) 1988-02-04
DK213983D0 (da) 1983-05-13
ES8400772A1 (es) 1983-11-01
DK149457B (da) 1986-06-16
CA1174623A (en) 1984-09-18
NO156052C (no) 1987-07-15
JPH0526469B2 (no) 1993-04-16
ES515713A0 (es) 1983-11-01
WO1983001074A1 (en) 1983-03-31
NO156052B (no) 1987-04-06
IT8249114A0 (it) 1982-09-14
US4601979A (en) 1986-07-22
JPS58501455A (ja) 1983-09-01
EP0088117A1 (en) 1983-09-14

Similar Documents

Publication Publication Date Title
DK189881A (da) Fremgangsmaade til fremstilling af aminocyklopentanalkensyrer eller estere deraf
NO830385L (no) Fremgangsmaate for fremstilling av en insulinopploesning
DK74282A (da) Fremgangsmaade til fremstilling af imidazodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf
NO156247C (no) Fremgangsmaate for fremstilling av humaninsulin eller treoin b30-estere av humaninsulin eller et salt eller kompleks derav.
DK163106C (da) Fremgangsmaade til fremstilling af antispasmatiske eller antirheumatiske praeparater til fastgoerelse paa huden
DK149457C (da) Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf
DK130983A (da) Fremgangsmaade til fremstilling af terapeutiske eller diagnostiske praeparater
DK374579A (da) Fremgangsmaade til fremstilling af et injucerbart insulinpraeparat
DK131083A (da) Fremgangsmaade til fremstilling af terapeutiske eller diagnostiske praeparater
DK98684D0 (da) Fremgangsmade til fremstilling af fedtsyreestere af ascorbinsyre
DK358183A (da) Fremgangsmaade til fremstilling af alfa-aryl-alkansyrer eller salte deraf
DK262982A (da) Fremgangsmaade til fremstilling af apovincaminsyreestere
DK280285D0 (da) Fremgangsmaade til fremstilling af ascorbinsyre
DK136481A (da) Fremgangsmaade til fremstilling af et insulinforstadium
DK316084D0 (da) Fremgangsmaade til fremstilling af phenol-aldehyd-baserede harpiksagtige termohaerdnende polyoler
DK149756C (da) Fremgangsmaade til fremstilling af insulin i form af okseinsulin, svineinsulin eller humant insulin, et hybrid heraf eller en insulin-analog
DK160043C (da) Analogifremgangsmaade til fremstilling af n-alk-2-en-4-yn-yl-benzothienylalkylaminer eller syreadditionssalte deraf
DK408782A (da) Fremgangsmaade til fremstilling af antranilsyreestere
DK492683D0 (da) Fremgangsmade til fremstilling af aminocykopentansyrer
DK435189D0 (da) Fremgangsmaade til fremstilling af phosphonoravsyretetramethylester eller phosphonoravsyretetraethylester
DK57182A (da) Fremgangsmaade til fremstilling af benzopyranoimidazoler ellersyreadditionssalte eller metalsalte deraf
DK162475C (da) Terapeutisk praeparat indeholdende hydrogenerede ergotalkaloider og heparin og fremgangsmaade til fremstiling af praeparatet
MX6686E (es) Procedimiento para preparar esteres de treonina b30 de insulina humana
DK310583D0 (da) Fremgangsmade til fremstilling af 7-amino-1-dethia-1-oxa-3-hydroxymethyl-cephem-4-carboxylsyrer
DK151020C (da) Fremgangsmaade til fremstilling af apovincaminsyreestere

Legal Events

Date Code Title Description
PBP Patent lapsed