DK1486571T3 - Fremgangsmåde til rekombinant fremstilling af polypeptider - Google Patents

Fremgangsmåde til rekombinant fremstilling af polypeptider

Info

Publication number
DK1486571T3
DK1486571T3 DK03012295T DK03012295T DK1486571T3 DK 1486571 T3 DK1486571 T3 DK 1486571T3 DK 03012295 T DK03012295 T DK 03012295T DK 03012295 T DK03012295 T DK 03012295T DK 1486571 T3 DK1486571 T3 DK 1486571T3
Authority
DK
Denmark
Prior art keywords
polypeptide
host cell
recombinant production
polypeptides
inclusion bodies
Prior art date
Application number
DK03012295T
Other languages
Danish (da)
English (en)
Inventor
Rainer Gruenbeck
Erhard Kopetzki
Friedrich Popp
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1486571T3 publication Critical patent/DK1486571T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK03012295T 2003-06-12 2003-06-12 Fremgangsmåde til rekombinant fremstilling af polypeptider DK1486571T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03012295A EP1486571B1 (de) 2003-06-12 2003-06-12 Verfahren zur rekombinanten Herstellung von Polypeptiden

Publications (1)

Publication Number Publication Date
DK1486571T3 true DK1486571T3 (da) 2006-04-18

Family

ID=33185854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03012295T DK1486571T3 (da) 2003-06-12 2003-06-12 Fremgangsmåde til rekombinant fremstilling af polypeptider

Country Status (13)

Country Link
US (1) US7034119B2 (de)
EP (1) EP1486571B1 (de)
JP (1) JP3783963B2 (de)
KR (1) KR100614020B1 (de)
CN (1) CN1284850C (de)
AT (1) ATE312939T1 (de)
CA (1) CA2467142C (de)
DE (1) DE60302776T2 (de)
DK (1) DK1486571T3 (de)
ES (1) ES2253604T3 (de)
IL (1) IL161994A (de)
MX (1) MXPA04004934A (de)
TW (1) TWI282370B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008054673A (ja) * 2006-08-03 2008-03-13 Hokkaido Univ 組み換え蛋白質の製造方法
BR112013004395A2 (pt) 2010-08-30 2019-09-24 Hoffmann La Roche tetranectina-apolipoproteína a-i, partículas de lipídio que a contém a sua utilização
RU2013111676A (ru) 2010-08-30 2014-10-10 Ф. Хоффманн-Ля Рош Аг Способ получения тетранектин-аполипопротеин а-i частицы, полученная таким образом липидная частица и ее применение
CN103025875A (zh) * 2010-08-30 2013-04-03 霍夫曼-拉罗奇有限公司 原核表达构建体
DE102011118029A1 (de) * 2011-06-20 2012-12-20 Universität Leipzig Modifizierte antibiotische Peptide mit variabler systemischer Freisetzung
MX2014001920A (es) 2011-08-25 2014-04-14 Hoffmann La Roche Proteina de fusion acortada de tetranectina-apolipoproteina a-i, una particula lipidica que la contiene, y usos de la misma.
KR20140135716A (ko) 2012-02-29 2014-11-26 에프. 호프만-라 로슈 아게 1→2 해독 프레임 이동의 감소 방법
EP2959006B1 (de) 2013-02-22 2018-07-18 F.Hoffmann-La Roche Ag Verwendung eines aminosäuren-auxotrophiegeheilten prokaryoten stammes für die rekombinante herstellung eines polypeptids
JP6576650B2 (ja) * 2015-03-03 2019-09-18 旭化成株式会社 グルコースの溶出抑制方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215540D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
US6291245B1 (en) * 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system

Also Published As

Publication number Publication date
ES2253604T3 (es) 2006-06-01
ATE312939T1 (de) 2005-12-15
CA2467142C (en) 2008-01-15
IL161994A (en) 2010-02-17
KR100614020B1 (ko) 2006-08-22
CN1572872A (zh) 2005-02-02
EP1486571B1 (de) 2005-12-14
TW200510544A (en) 2005-03-16
CN1284850C (zh) 2006-11-15
JP3783963B2 (ja) 2006-06-07
US20050003485A1 (en) 2005-01-06
TWI282370B (en) 2007-06-11
IL161994A0 (en) 2005-11-20
KR20040107397A (ko) 2004-12-20
JP2005000170A (ja) 2005-01-06
US7034119B2 (en) 2006-04-25
DE60302776T2 (de) 2006-08-17
DE60302776D1 (de) 2006-01-19
CA2467142A1 (en) 2004-12-12
MXPA04004934A (es) 2005-08-10
EP1486571A1 (de) 2004-12-15

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