DK146689C - Analogifremgangsmaade til fremstilling af 1',2',3',4'-tetrahydro-spiro(imidazolidin-4,4'-quinolin eller -pyrido(2,3-b)pyridin)-2,5-dion-forbindelser eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 1',2',3',4'-tetrahydro-spiro(imidazolidin-4,4'-quinolin eller -pyrido(2,3-b)pyridin)-2,5-dion-forbindelser eller syreadditionssalte deraf

Info

Publication number
DK146689C
DK146689C DK252880A DK252880A DK146689C DK 146689 C DK146689 C DK 146689C DK 252880 A DK252880 A DK 252880A DK 252880 A DK252880 A DK 252880A DK 146689 C DK146689 C DK 146689C
Authority
DK
Denmark
Prior art keywords
imidazolidin
pyrido
spiro
analogy
tetrahydro
Prior art date
Application number
DK252880A
Other languages
Danish (da)
English (en)
Other versions
DK146689B (da
DK252880A (da
Inventor
Reinhard Sarges
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK252880A publication Critical patent/DK252880A/da
Publication of DK146689B publication Critical patent/DK146689B/da
Application granted granted Critical
Publication of DK146689C publication Critical patent/DK146689C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK252880A 1979-06-13 1980-06-12 Analogifremgangsmaade til fremstilling af 1',2',3',4'-tetrahydro-spiro(imidazolidin-4,4'-quinolin eller -pyrido(2,3-b)pyridin)-2,5-dion-forbindelser eller syreadditionssalte deraf DK146689C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/048,004 US4235911A (en) 1979-06-13 1979-06-13 Hydantoin derivatives
US4800479 1979-06-13

Publications (3)

Publication Number Publication Date
DK252880A DK252880A (da) 1980-12-14
DK146689B DK146689B (da) 1983-12-05
DK146689C true DK146689C (da) 1984-06-18

Family

ID=21952241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK252880A DK146689C (da) 1979-06-13 1980-06-12 Analogifremgangsmaade til fremstilling af 1',2',3',4'-tetrahydro-spiro(imidazolidin-4,4'-quinolin eller -pyrido(2,3-b)pyridin)-2,5-dion-forbindelser eller syreadditionssalte deraf

Country Status (7)

Country Link
US (1) US4235911A (no)
EP (1) EP0021704B1 (no)
JP (1) JPS562986A (no)
DE (1) DE3062884D1 (no)
DK (1) DK146689C (no)
GR (1) GR69260B (no)
IE (1) IE49841B1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307108A (en) * 1979-12-26 1981-12-22 Pfizer Inc. Method for lowering sorbitol levels using spiro-imides
FR2525603A1 (fr) * 1982-04-27 1983-10-28 Adir Benzoazacycloalkyl-spiro-imidazolinines, leur preparation et leur application en therapeutique
FR2544317B2 (fr) * 1983-04-12 1985-07-05 Adir Benzoazacycloalkyl-spiro-imidazolidines et les compositions pharmaceutiques les contenant
US4656169A (en) * 1984-08-14 1987-04-07 Pfizer Inc. Tetracyclic spiro-hydantoin aldose reductase inhibitors and compositions
US4966911A (en) * 1984-11-20 1990-10-30 Washington Research Foundation Immunoregulatory agents
US5340829A (en) * 1984-11-20 1994-08-23 Washington Research Foundation Immunoregulatory agents
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use
DE3621396A1 (de) * 1986-06-26 1988-01-14 Bosch Gmbh Robert Transistoranordnung mit einem endstufentransistor
EP0306525A4 (en) * 1987-03-20 1991-04-24 Alcon Laboratories Inc Use of aldose reductase inhibitors to enhance insulin sensitivity in diabetes mellitus
MX12896A (es) * 1987-09-04 1993-06-01 Pfizer Procedimiento para preparar un compuesto de espiro-heteroazolonas
WO1992000071A1 (en) * 1989-02-10 1992-01-09 Washington Research Foundation Immunoregulatory agents
DE10210195B4 (de) 2002-03-07 2005-12-15 Schwarz Pharma Ag Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz
US6872827B2 (en) * 2002-04-26 2005-03-29 Chembridge Research Laboratories, Inc. Somatostatin analogue compounds
KR100454750B1 (ko) * 2002-06-20 2004-11-03 삼성에스디아이 주식회사 유기 전계 발광 소자용 청색 발광 화합물 및 이를 사용한유기 전계 발광 소자

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4147795A (en) * 1977-02-11 1979-04-03 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4147797A (en) * 1978-08-11 1979-04-03 Pfizer Inc. Spiro-furanohydantoin derivatives

Also Published As

Publication number Publication date
EP0021704A1 (en) 1981-01-07
EP0021704B1 (en) 1983-04-27
JPS6152834B2 (no) 1986-11-14
IE801212L (en) 1980-12-13
US4235911A (en) 1980-11-25
DK146689B (da) 1983-12-05
GR69260B (no) 1982-05-12
DE3062884D1 (en) 1983-06-01
IE49841B1 (en) 1985-12-25
JPS562986A (en) 1981-01-13
DK252880A (da) 1980-12-14

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