DK1462439T3 - Hidtil ukendte stabile krystaller af substitueret phenylpropionsyrederivat og fremgangsmåder til fremstilling af den samme - Google Patents
Hidtil ukendte stabile krystaller af substitueret phenylpropionsyrederivat og fremgangsmåder til fremstilling af den sammeInfo
- Publication number
- DK1462439T3 DK1462439T3 DK02783815T DK02783815T DK1462439T3 DK 1462439 T3 DK1462439 T3 DK 1462439T3 DK 02783815 T DK02783815 T DK 02783815T DK 02783815 T DK02783815 T DK 02783815T DK 1462439 T3 DK1462439 T3 DK 1462439T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- methods
- same
- acid derivative
- phenylpropionic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001377077 | 2001-12-11 | ||
| PCT/JP2002/012892 WO2003050077A1 (fr) | 2001-12-11 | 2002-12-10 | Cristaux stables de derive d'acide phenylpropionique substitue et procede de production associe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1462439T3 true DK1462439T3 (da) | 2008-04-21 |
Family
ID=19185129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02783815T DK1462439T3 (da) | 2001-12-11 | 2002-12-10 | Hidtil ukendte stabile krystaller af substitueret phenylpropionsyrederivat og fremgangsmåder til fremstilling af den samme |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7279596B2 (de) |
| EP (1) | EP1462439B1 (de) |
| JP (1) | JP4424728B2 (de) |
| KR (1) | KR100876849B1 (de) |
| CN (1) | CN1312121C (de) |
| AT (1) | ATE390406T1 (de) |
| AU (1) | AU2002349538B2 (de) |
| CA (1) | CA2469882C (de) |
| CY (1) | CY1107417T1 (de) |
| DE (1) | DE60225841T2 (de) |
| DK (1) | DK1462439T3 (de) |
| ES (1) | ES2302857T3 (de) |
| PT (1) | PT1462439E (de) |
| WO (1) | WO2003050077A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006016637A1 (ja) * | 2004-08-11 | 2006-02-16 | Kyorin Pharmaceutical Co., Ltd. | 新規環状アミノ安息香酸誘導体 |
| JP2007001912A (ja) * | 2005-06-22 | 2007-01-11 | Univ Of Tokyo | 置換フェニルプロピオン酸誘導体 |
| EP2091910B1 (de) * | 2006-12-06 | 2014-08-20 | Conatus Pharmaceuticals, Inc. | Kristalline formen von (3 s) -3- [n- (n' - (2-tert-butylphenyl) oxamyl) alaninyl] amino-5- (2 ', 3 ', 5 ', 6 ' -tetrafluoro phenoxy) -4-oxo-pentansäure |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4618845B2 (ja) * | 1999-06-09 | 2011-01-26 | 杏林製薬株式会社 | ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体 |
| CA2385083C (en) * | 1999-09-17 | 2007-06-05 | Kyorin Pharmaceutical Co., Ltd. | O-anisamide derivatives |
| TWI262185B (en) | 1999-10-01 | 2006-09-21 | Eisai Co Ltd | Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives |
-
2002
- 2002-12-10 WO PCT/JP2002/012892 patent/WO2003050077A1/ja active IP Right Grant
- 2002-12-10 US US10/497,174 patent/US7279596B2/en not_active Expired - Fee Related
- 2002-12-10 CN CNB028245946A patent/CN1312121C/zh not_active Expired - Fee Related
- 2002-12-10 AU AU2002349538A patent/AU2002349538B2/en not_active Ceased
- 2002-12-10 EP EP02783815A patent/EP1462439B1/de not_active Expired - Lifetime
- 2002-12-10 ES ES02783815T patent/ES2302857T3/es not_active Expired - Lifetime
- 2002-12-10 KR KR1020047008935A patent/KR100876849B1/ko not_active IP Right Cessation
- 2002-12-10 AT AT02783815T patent/ATE390406T1/de active
- 2002-12-10 DE DE60225841T patent/DE60225841T2/de not_active Expired - Lifetime
- 2002-12-10 PT PT02783815T patent/PT1462439E/pt unknown
- 2002-12-10 JP JP2003551104A patent/JP4424728B2/ja not_active Expired - Fee Related
- 2002-12-10 DK DK02783815T patent/DK1462439T3/da active
- 2002-12-10 CA CA002469882A patent/CA2469882C/en not_active Expired - Fee Related
-
2008
- 2008-04-21 CY CY20081100446T patent/CY1107417T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2469882C (en) | 2009-09-29 |
| AU2002349538B2 (en) | 2006-04-27 |
| JP4424728B2 (ja) | 2010-03-03 |
| KR20040075000A (ko) | 2004-08-26 |
| EP1462439A4 (de) | 2006-02-01 |
| CA2469882A1 (en) | 2003-06-19 |
| ES2302857T3 (es) | 2008-08-01 |
| CN1602295A (zh) | 2005-03-30 |
| JPWO2003050077A1 (ja) | 2005-04-21 |
| EP1462439B1 (de) | 2008-03-26 |
| WO2003050077A1 (fr) | 2003-06-19 |
| EP1462439A1 (de) | 2004-09-29 |
| KR100876849B1 (ko) | 2008-12-31 |
| ATE390406T1 (de) | 2008-04-15 |
| US20050228050A1 (en) | 2005-10-13 |
| DE60225841T2 (de) | 2009-05-14 |
| AU2002349538A1 (en) | 2003-06-23 |
| PT1462439E (pt) | 2008-04-10 |
| CN1312121C (zh) | 2007-04-25 |
| DE60225841D1 (de) | 2008-05-08 |
| CY1107417T1 (el) | 2012-12-19 |
| US7279596B2 (en) | 2007-10-09 |
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