DK1446380T3 - Formoteroltartrafremgangsmåde og polymorf - Google Patents
Formoteroltartrafremgangsmåde og polymorfInfo
- Publication number
- DK1446380T3 DK1446380T3 DK02786502T DK02786502T DK1446380T3 DK 1446380 T3 DK1446380 T3 DK 1446380T3 DK 02786502 T DK02786502 T DK 02786502T DK 02786502 T DK02786502 T DK 02786502T DK 1446380 T3 DK1446380 T3 DK 1446380T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymorph
- formoterol
- tartar
- procedure
- tartrate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/037,183 US6472563B1 (en) | 2001-11-09 | 2001-11-09 | Formoterol tartrate process and polymorph |
PCT/US2002/034118 WO2003042165A1 (en) | 2001-11-09 | 2002-10-23 | Formoterol tartrate process and polymorph |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1446380T3 true DK1446380T3 (da) | 2010-01-04 |
Family
ID=21892899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02786502T DK1446380T3 (da) | 2001-11-09 | 2002-10-23 | Formoteroltartrafremgangsmåde og polymorf |
Country Status (13)
Country | Link |
---|---|
US (10) | US6472563B1 (lv) |
EP (3) | EP2305635B1 (lv) |
JP (1) | JP4271574B2 (lv) |
AT (1) | ATE450497T1 (lv) |
AU (2) | AU2002349914B2 (lv) |
CA (1) | CA2477642C (lv) |
CY (1) | CY1109832T1 (lv) |
DE (1) | DE60234629D1 (lv) |
DK (1) | DK1446380T3 (lv) |
ES (2) | ES2336436T3 (lv) |
PT (1) | PT1446380E (lv) |
SI (1) | SI1446380T1 (lv) |
WO (1) | WO2003042165A1 (lv) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6472563B1 (en) * | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
US7524515B2 (en) * | 2003-01-10 | 2009-04-28 | Mutual Pharmaceuticals, Inc. | Pharmaceutical safety dosage forms |
GB0312148D0 (en) | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
GB0315889D0 (en) * | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
WO2005019227A1 (en) * | 2003-08-22 | 2005-03-03 | Orchid Chemicals & Pharmaceuticals Ltd | Process for the preparation of cephalosporin antibiotic |
UA83504C2 (en) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
US20060160841A1 (en) * | 2005-01-19 | 2006-07-20 | Chenkou Wei | Crystallization via high-shear transformation |
US8039461B1 (en) | 2006-11-10 | 2011-10-18 | Pisgah Laboratories, Inc. | Physical states of a pharmaceutical drug substance |
US7718649B1 (en) | 2006-11-10 | 2010-05-18 | Pisgah Labs, Inc. | Physical states of a pharmaceutical drug substance |
US8501994B2 (en) | 2007-08-28 | 2013-08-06 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
US7718822B2 (en) * | 2007-08-28 | 2010-05-18 | Sepracor Inc. | Carbamate Stereoisomer |
CN101393186A (zh) * | 2007-09-21 | 2009-03-25 | 北京德众万全药物技术开发有限公司 | 一种hplc法分离分析酒石酸福莫特罗手性异构体的方法 |
EP3311820A1 (en) * | 2008-02-26 | 2018-04-25 | Sunovion Respiratory Development Inc. | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
US20100055045A1 (en) * | 2008-02-26 | 2010-03-04 | William Gerhart | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
WO2009106997A2 (en) * | 2008-02-28 | 2009-09-03 | Actavis Group Ptc Ehf | Amorphous arformoterol l-(+)-tartrate |
US8883863B1 (en) | 2008-04-03 | 2014-11-11 | Pisgah Laboratories, Inc. | Safety of psuedoephedrine drug products |
WO2010128355A2 (en) | 2008-12-26 | 2010-11-11 | Actavis Group Ptc Ehf | Improved processes for preparing substantially pure arformoterol and its intermediates |
ME02398B (me) * | 2009-10-02 | 2016-09-20 | Chiesi Farm Spa | Farmaceutske aerosolne formulacije formoterola i beklometazon dipropionata |
IT1399912B1 (it) * | 2010-04-29 | 2013-05-09 | Lundbeck Pharmaceuticals Italy S Pa | Processo di preparazione di ritodrina cloridrato. |
JP6210988B2 (ja) | 2011-09-19 | 2017-10-11 | オレクソ・アクチエボラゲット | オピオイド依存を治療するための新規乱用耐性医薬組成物 |
US9309186B2 (en) | 2012-03-12 | 2016-04-12 | Laboratorios Lesvi S.L. | Polymorphic form of a long-acting beta-2 adrenoceptor agonist |
EP3473615B1 (en) | 2013-02-28 | 2022-01-19 | Journey Medical Corporation | Glycopyrrolate salts |
US9006462B2 (en) | 2013-02-28 | 2015-04-14 | Dermira, Inc. | Glycopyrrolate salts |
US8558008B2 (en) | 2013-02-28 | 2013-10-15 | Dermira, Inc. | Crystalline glycopyrrolate tosylate |
CN105431409A (zh) * | 2013-05-17 | 2016-03-23 | 格伦马克制药有限公司 | 制备阿福特罗或其盐的方法 |
CN107151219A (zh) * | 2017-05-23 | 2017-09-12 | 北京万全德众医药生物技术有限公司 | 酒石酸阿福特罗的精制方法 |
CN111909049B (zh) * | 2020-09-03 | 2023-04-25 | 扬州中宝药业股份有限公司 | 一种酒石酸阿福特罗精制的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2005492A6 (es) | 1987-12-23 | 1989-03-01 | Lasa Lab | Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i). |
ES2031407A6 (es) | 1988-10-05 | 1992-12-01 | Lasa Lab | Mejoras introducidas en el objeto de la patente principal n{ 8703715 por: procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2-((2-(4-metoxifenil)-1-metiletil)amino)etil)fenil)formamida". |
SE8901060D0 (sv) | 1989-03-28 | 1989-03-28 | Draco Ab | New compounds |
SE9003057D0 (sv) | 1990-09-26 | 1990-09-26 | Astra Ab | New process |
US5434304A (en) * | 1990-09-26 | 1995-07-18 | Aktiebolaget Astra | Process for preparing formoterol and related compounds |
US6040344A (en) | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
DE59904648D1 (de) * | 1998-08-04 | 2003-04-24 | Jago Res Ag Muttenz | Medizinische aerosolformulierungen |
US6472563B1 (en) | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
-
2001
- 2001-11-09 US US10/037,183 patent/US6472563B1/en not_active Expired - Lifetime
-
2002
- 2002-09-10 US US10/238,204 patent/US6720453B2/en not_active Expired - Lifetime
- 2002-10-23 EP EP10178918.8A patent/EP2305635B1/en not_active Expired - Lifetime
- 2002-10-23 CA CA2477642A patent/CA2477642C/en not_active Expired - Lifetime
- 2002-10-23 WO PCT/US2002/034118 patent/WO2003042165A1/en active Application Filing
- 2002-10-23 ES ES02786502T patent/ES2336436T3/es not_active Expired - Lifetime
- 2002-10-23 EP EP09172739A patent/EP2165999A1/en not_active Ceased
- 2002-10-23 JP JP2003544002A patent/JP4271574B2/ja not_active Expired - Lifetime
- 2002-10-23 SI SI200230882T patent/SI1446380T1/sl unknown
- 2002-10-23 ES ES10178918.8T patent/ES2685100T3/es not_active Expired - Lifetime
- 2002-10-23 DK DK02786502T patent/DK1446380T3/da active
- 2002-10-23 PT PT02786502T patent/PT1446380E/pt unknown
- 2002-10-23 EP EP02786502A patent/EP1446380B1/en not_active Expired - Lifetime
- 2002-10-23 AU AU2002349914A patent/AU2002349914B2/en not_active Expired
- 2002-10-23 DE DE60234629T patent/DE60234629D1/de not_active Expired - Lifetime
- 2002-10-23 AT AT02786502T patent/ATE450497T1/de active
-
2004
- 2004-03-23 US US10/806,993 patent/US20040176450A1/en not_active Abandoned
-
2005
- 2005-02-07 US US11/052,268 patent/US7145036B2/en not_active Expired - Lifetime
-
2006
- 2006-08-04 US US11/462,637 patent/US7342132B2/en not_active Expired - Lifetime
-
2008
- 2008-01-14 US US12/013,848 patent/US7479572B2/en not_active Expired - Lifetime
- 2008-12-04 AU AU2008253696A patent/AU2008253696B2/en not_active Expired
- 2008-12-05 US US12/329,196 patent/US7732641B2/en not_active Expired - Lifetime
-
2010
- 2010-01-22 CY CY20101100073T patent/CY1109832T1/el unknown
- 2010-04-26 US US12/767,043 patent/US8110706B2/en not_active Expired - Fee Related
- 2010-06-07 US US12/794,991 patent/US7964753B2/en not_active Expired - Fee Related
-
2012
- 2012-01-04 US US13/343,118 patent/US20120108670A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1446380T3 (da) | Formoteroltartrafremgangsmåde og polymorf | |
LU92520I2 (fr) | Bédaquiline, ou son sel d'addition d'acide ou de base pharmaceutiquement acceptable, y compris le fumarate de bédaquiline | |
WO2000021487A3 (en) | Formoterol polymorphs | |
MY140236A (en) | Diarylether compounds useful as opioid receptor antagonists | |
NO20012921L (no) | Fenylglycin-derivater | |
NO20040680D0 (no) | Nye dihydropterinonerfremgangsmate for fremstilling derav og deres anvendelse som legemiddel | |
TW200716520A (en) | 3,4-di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | |
IS6859A (is) | Kristölluð form atorvastatíns | |
NO20040794L (no) | (-)-1-(3,4-Diklorfenyl)-3-azabicyklo[3.1.0]heksan, forbindelser derav og anvendelser som en dopamin-gjenopptaks-inhibitor. | |
NO329883B1 (no) | Fremgangsmate for fremstilling av prostaglandiner og analoger derav og av mellomforbindelser, og forbindelser fremstilt derved | |
CY1108808T1 (el) | Ενωσεις μοτιλιδης | |
NO20044442L (no) | Fosfatprodroger av fluoroksindoler | |
HUP0303639A2 (hu) | Új amlodipin-kamzilát és eljárás annak előállítására | |
EA200301276A1 (ru) | Новые производные сульфоновых кислот | |
RU2002130710A (ru) | Производное пиридин-1-оксида и способ его преобразования в фармацевтически эффективные соединения | |
HK1073295A1 (en) | Acetyl l-carnitine acid fumarate and process for preparing the same | |
NO20040388L (no) | Fremgangsmåte for fremstilling av beraprost og salter derav, samt forbindelser som er mellomprodukter i fremgangsmåten | |
IS7289A (is) | Kristallaður venlafaxínbasi og nýir fjölgervingarvenlafaxínhýdróklóríðs, aðferðir til að framleiðaþá | |
NO20042681L (no) | Ny krystallinsk polymorf av venlafaxine-hydroklorid og fremgangsmater for fremstilling derav | |
IL166103A0 (en) | Pyrrolidine derivatives and their use | |
NO995676L (no) | Isoftalamid derivat som gul polymorf | |
EE200200583A (et) | (E)-N-(6,6-dimetüül-2-hepteen-4-ünüül)-N-metüül-1-naftaleenmetaanamiini (terbinafiin) valmistamise meetod | |
WO2002053537A8 (en) | Process for preparing (±) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine | |
NO20042469L (no) | N-metylhomocysteiner, anvendelse derav og fremgangsmate for fremstilling derav | |
DE60235119D1 (en) | Bipyridinylderivate als hochselektive cyclooxygenase-2-inhibitoren |