DK144418C - Analogifremgangsmaade til fremstilling af 2,4-diamino-5-benzylpyrimidiner - Google Patents
Analogifremgangsmaade til fremstilling af 2,4-diamino-5-benzylpyrimidinerInfo
- Publication number
- DK144418C DK144418C DK500178A DK500178A DK144418C DK 144418 C DK144418 C DK 144418C DK 500178 A DK500178 A DK 500178A DK 500178 A DK500178 A DK 500178A DK 144418 C DK144418 C DK 144418C
- Authority
- DK
- Denmark
- Prior art keywords
- benzylpyrimidines
- diamino
- preparation
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/08—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK299080A DK299080A (da) | 1977-11-10 | 1980-07-10 | Benzaldehydderivater |
| DK299180A DK144698C (da) | 1977-11-10 | 1980-07-10 | 2,4-diamino-6-halogen-5-benzylpyrimidiner til anvendelse som mellemprodukter ved fremstilling af 2,4-diamino-5-benzylpyrimidiner |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU78487 | 1977-11-10 | ||
| LU78487 | 1977-11-10 | ||
| CH977678 | 1978-09-19 | ||
| CH977678 | 1978-09-19 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK500178A DK500178A (da) | 1979-05-11 |
| DK144418B DK144418B (da) | 1982-03-08 |
| DK144418C true DK144418C (da) | 1982-08-09 |
Family
ID=25705315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK500178A DK144418C (da) | 1977-11-10 | 1978-11-09 | Analogifremgangsmaade til fremstilling af 2,4-diamino-5-benzylpyrimidiner |
Country Status (22)
| Country | Link |
|---|---|
| EP (3) | EP0003212B1 (hu) |
| JP (1) | JPS5476586A (hu) |
| AR (2) | AR228423A1 (hu) |
| AT (1) | AT359070B (hu) |
| AU (1) | AU527943B2 (hu) |
| BR (1) | BR7807425A (hu) |
| CA (1) | CA1108611A (hu) |
| DE (1) | DE2847825A1 (hu) |
| DK (1) | DK144418C (hu) |
| ES (2) | ES474921A1 (hu) |
| FI (1) | FI783368A (hu) |
| FR (4) | FR2422647A1 (hu) |
| GB (3) | GB2007669B (hu) |
| GR (1) | GR71725B (hu) |
| IL (1) | IL55869A (hu) |
| IT (1) | IT1100210B (hu) |
| MC (1) | MC1222A1 (hu) |
| NL (1) | NL7811170A (hu) |
| NO (1) | NO783775L (hu) |
| PH (1) | PH15918A (hu) |
| PT (1) | PT68773A (hu) |
| SE (1) | SE7811593L (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1138146B (it) * | 1981-08-11 | 1986-09-17 | Proter Spa | Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina |
| FR2516081B1 (fr) * | 1981-11-09 | 1987-05-29 | Wellcome Found | Synthese de benzylpyrimidines et produits intermediaires pour cette synthese |
| DE3304202A1 (de) * | 1983-02-08 | 1984-08-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von aromatischen aldehyden |
| DE3603577A1 (de) * | 1986-02-06 | 1987-08-13 | Joachim K Prof Dr Seydel | Neue substituierte 2,4-diamino-5-benzylpyrimidine, deren herstellung und deren verwendung als arzneimittel mit antibakterieller wirksamkeit |
| EP0639075A1 (en) * | 1990-11-14 | 1995-02-22 | Chiron Corporation | Specific inhibition of dihydrofolate reductase and compounds therefor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2165362A1 (de) * | 1970-12-29 | 1972-07-27 | Nisshin Flour Milling Co. Ltd., Tokio | .-Verfahren zur Herstellung von Pyrimidinderivaten |
| NL7200058A (hu) * | 1971-01-21 | 1972-07-25 | ||
| IL38276A (en) * | 1971-12-01 | 1976-09-30 | Plantex Ltd | Process for the preparation of 2,4-diamino-5-substituted benzylpyrimidines |
| BE798724A (fr) * | 1973-04-26 | 1973-08-16 | En Abrege Socechim Soc Et Chim | Nouveaux composes chimiques |
| SE419444B (sv) * | 1973-11-08 | 1981-08-03 | Hoffmann La Roche | Forfarande for framstellning av nya 2,4-diamino-5-bensylpyrimidinderivat |
| CH605828A5 (hu) * | 1974-12-24 | 1978-10-13 | Hoffmann La Roche | |
| DE2635765C3 (de) * | 1976-08-09 | 1979-02-08 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin |
-
1978
- 1978-04-08 GR GR57610A patent/GR71725B/el unknown
- 1978-11-03 EP EP78101300A patent/EP0003212B1/de not_active Expired
- 1978-11-03 EP EP81100161A patent/EP0032395B1/de not_active Expired
- 1978-11-03 AU AU41323/78A patent/AU527943B2/en not_active Expired
- 1978-11-03 DE DE19782847825 patent/DE2847825A1/de not_active Withdrawn
- 1978-11-03 IL IL55869A patent/IL55869A/xx unknown
- 1978-11-03 EP EP81100160A patent/EP0035624B1/de not_active Expired
- 1978-11-06 FI FI783368A patent/FI783368A/fi unknown
- 1978-11-06 CA CA315,867A patent/CA1108611A/en not_active Expired
- 1978-11-07 MC MC781339A patent/MC1222A1/xx unknown
- 1978-11-08 ES ES474921A patent/ES474921A1/es not_active Expired
- 1978-11-08 FR FR7831549A patent/FR2422647A1/fr active Granted
- 1978-11-09 AT AT803378A patent/AT359070B/de not_active IP Right Cessation
- 1978-11-09 GB GB7843861A patent/GB2007669B/en not_active Expired
- 1978-11-09 GB GB8114951A patent/GB2087378B/en not_active Expired
- 1978-11-09 SE SE7811593A patent/SE7811593L/xx unknown
- 1978-11-09 GB GB8114950A patent/GB2086882B/en not_active Expired
- 1978-11-09 IT IT29638/78A patent/IT1100210B/it active
- 1978-11-09 JP JP13740378A patent/JPS5476586A/ja active Pending
- 1978-11-09 NO NO783775A patent/NO783775L/no unknown
- 1978-11-09 DK DK500178A patent/DK144418C/da not_active IP Right Cessation
- 1978-11-09 PT PT68773A patent/PT68773A/pt unknown
- 1978-11-10 AR AR274416A patent/AR228423A1/es active
- 1978-11-10 NL NL7811170A patent/NL7811170A/xx not_active Application Discontinuation
- 1978-11-10 PH PH21791A patent/PH15918A/en unknown
- 1978-11-10 BR BR7807425A patent/BR7807425A/pt unknown
-
1979
- 1979-05-16 ES ES481038A patent/ES481038A1/es not_active Expired
- 1979-06-22 FR FR7916101A patent/FR2422648A1/fr active Granted
- 1979-06-22 FR FR7916100A patent/FR2422632A1/fr active Granted
- 1979-06-22 FR FR7916099A patent/FR2422404A1/fr active Granted
- 1979-08-09 AR AR277656A patent/AR222831A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |