FR2422404A1 - Compositions pharmaceutiques a base de 2,4-diamino-5-benzylpyrimidine et d'un sulfamide; et leur preparation - Google Patents
Compositions pharmaceutiques a base de 2,4-diamino-5-benzylpyrimidine et d'un sulfamide; et leur preparationInfo
- Publication number
- FR2422404A1 FR2422404A1 FR7916099A FR7916099A FR2422404A1 FR 2422404 A1 FR2422404 A1 FR 2422404A1 FR 7916099 A FR7916099 A FR 7916099A FR 7916099 A FR7916099 A FR 7916099A FR 2422404 A1 FR2422404 A1 FR 2422404A1
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical compositions
- benzylpyrimidine
- diamino
- preparation
- sulfamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/08—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La présente invention concerne des nouvelles compositions pharmaceutiques et leur préparation. Les compositions pharmaceutiques selon l'invention se caractérisent par le fait qu'elles contiennent : 1. Une 2,4-diamino-5-benzylpyrimidine de formule :
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU78487 | 1977-11-10 | ||
CH977678 | 1978-09-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2422404A1 true FR2422404A1 (fr) | 1979-11-09 |
FR2422404B1 FR2422404B1 (fr) | 1983-02-04 |
Family
ID=25705315
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7831549A Granted FR2422647A1 (fr) | 1977-11-10 | 1978-11-08 | Nouvelles 2,4-diamino-5-benzylpyrimidines, leur preparation et leur application en tant que medicaments |
FR7916099A Granted FR2422404A1 (fr) | 1977-11-10 | 1979-06-22 | Compositions pharmaceutiques a base de 2,4-diamino-5-benzylpyrimidine et d'un sulfamide; et leur preparation |
FR7916101A Granted FR2422648A1 (fr) | 1977-11-10 | 1979-06-22 | Nouvelles 2,4-diamino-5-benzyl-6-halogenopyrimidines |
FR7916100A Granted FR2422632A1 (fr) | 1977-11-10 | 1979-06-22 | Nouveaux benzaldehydes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7831549A Granted FR2422647A1 (fr) | 1977-11-10 | 1978-11-08 | Nouvelles 2,4-diamino-5-benzylpyrimidines, leur preparation et leur application en tant que medicaments |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7916101A Granted FR2422648A1 (fr) | 1977-11-10 | 1979-06-22 | Nouvelles 2,4-diamino-5-benzyl-6-halogenopyrimidines |
FR7916100A Granted FR2422632A1 (fr) | 1977-11-10 | 1979-06-22 | Nouveaux benzaldehydes |
Country Status (22)
Country | Link |
---|---|
EP (3) | EP0035624B1 (fr) |
JP (1) | JPS5476586A (fr) |
AR (2) | AR228423A1 (fr) |
AT (1) | AT359070B (fr) |
AU (1) | AU527943B2 (fr) |
BR (1) | BR7807425A (fr) |
CA (1) | CA1108611A (fr) |
DE (1) | DE2847825A1 (fr) |
DK (1) | DK144418C (fr) |
ES (2) | ES474921A1 (fr) |
FI (1) | FI783368A (fr) |
FR (4) | FR2422647A1 (fr) |
GB (3) | GB2007669B (fr) |
GR (1) | GR71725B (fr) |
IL (1) | IL55869A (fr) |
IT (1) | IT1100210B (fr) |
MC (1) | MC1222A1 (fr) |
NL (1) | NL7811170A (fr) |
NO (1) | NO783775L (fr) |
PH (1) | PH15918A (fr) |
PT (1) | PT68773A (fr) |
SE (1) | SE7811593L (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1138146B (it) * | 1981-08-11 | 1986-09-17 | Proter Spa | Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina |
FR2516081B1 (fr) * | 1981-11-09 | 1987-05-29 | Wellcome Found | Synthese de benzylpyrimidines et produits intermediaires pour cette synthese |
DE3304202A1 (de) * | 1983-02-08 | 1984-08-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von aromatischen aldehyden |
DE3603577A1 (de) * | 1986-02-06 | 1987-08-13 | Joachim K Prof Dr Seydel | Neue substituierte 2,4-diamino-5-benzylpyrimidine, deren herstellung und deren verwendung als arzneimittel mit antibakterieller wirksamkeit |
PT99514B (pt) * | 1990-11-14 | 1999-04-30 | Chiron Corp | Processo de preparacao de compostos para o tratamento de infeccoes fungicas |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2165362A1 (de) * | 1970-12-29 | 1972-07-27 | Nisshin Flour Milling Co. Ltd., Tokio | .-Verfahren zur Herstellung von Pyrimidinderivaten |
NL7200058A (fr) * | 1971-01-21 | 1972-07-25 | ||
IL38276A (en) * | 1971-12-01 | 1976-09-30 | Plantex Ltd | Process for the preparation of 2,4-diamino-5-substituted benzylpyrimidines |
BE798724A (fr) * | 1973-04-26 | 1973-08-16 | En Abrege Socechim Soc Et Chim | Nouveaux composes chimiques |
JPS6119628B2 (fr) * | 1973-11-08 | 1986-05-17 | Efu Hofuman Ra Roshu Unto Co Ag | |
CH605828A5 (fr) * | 1974-12-24 | 1978-10-13 | Hoffmann La Roche | |
DE2635765C3 (de) * | 1976-08-09 | 1979-02-08 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin |
-
1978
- 1978-04-08 GR GR57610A patent/GR71725B/el unknown
- 1978-11-03 AU AU41323/78A patent/AU527943B2/en not_active Expired
- 1978-11-03 EP EP81100160A patent/EP0035624B1/fr not_active Expired
- 1978-11-03 EP EP78101300A patent/EP0003212B1/fr not_active Expired
- 1978-11-03 DE DE19782847825 patent/DE2847825A1/de not_active Withdrawn
- 1978-11-03 EP EP81100161A patent/EP0032395B1/fr not_active Expired
- 1978-11-03 IL IL55869A patent/IL55869A/xx unknown
- 1978-11-06 CA CA315,867A patent/CA1108611A/fr not_active Expired
- 1978-11-06 FI FI783368A patent/FI783368A/fi unknown
- 1978-11-07 MC MC781339A patent/MC1222A1/fr unknown
- 1978-11-08 FR FR7831549A patent/FR2422647A1/fr active Granted
- 1978-11-08 ES ES474921A patent/ES474921A1/es not_active Expired
- 1978-11-09 PT PT68773A patent/PT68773A/pt unknown
- 1978-11-09 IT IT29638/78A patent/IT1100210B/it active
- 1978-11-09 NO NO783775A patent/NO783775L/no unknown
- 1978-11-09 AT AT803378A patent/AT359070B/de not_active IP Right Cessation
- 1978-11-09 GB GB7843861A patent/GB2007669B/en not_active Expired
- 1978-11-09 GB GB8114951A patent/GB2087378B/en not_active Expired
- 1978-11-09 JP JP13740378A patent/JPS5476586A/ja active Pending
- 1978-11-09 SE SE7811593A patent/SE7811593L/xx unknown
- 1978-11-09 GB GB8114950A patent/GB2086882B/en not_active Expired
- 1978-11-09 DK DK500178A patent/DK144418C/da not_active IP Right Cessation
- 1978-11-10 AR AR274416A patent/AR228423A1/es active
- 1978-11-10 BR BR7807425A patent/BR7807425A/pt unknown
- 1978-11-10 PH PH21791A patent/PH15918A/en unknown
- 1978-11-10 NL NL7811170A patent/NL7811170A/xx not_active Application Discontinuation
-
1979
- 1979-05-16 ES ES481038A patent/ES481038A1/es not_active Expired
- 1979-06-22 FR FR7916099A patent/FR2422404A1/fr active Granted
- 1979-06-22 FR FR7916101A patent/FR2422648A1/fr active Granted
- 1979-06-22 FR FR7916100A patent/FR2422632A1/fr active Granted
- 1979-08-09 AR AR277656A patent/AR222831A1/es active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2446832A1 (fr) | Octahydro-pyrazolo(3,4-g)quinoleines et leur utilisation therapeutique | |
FR2400517A1 (fr) | Triazolo-2,4-benzodiazepines et leur utilisation therapeutique | |
FR2293485A1 (fr) | Compositions lubrifiantes ameliorees par l'addition de copolymeres greffes | |
FR2361901A1 (fr) | Derives de substitution de nucleotides et medicament contenant ces substances | |
FR2446283A1 (fr) | Phenoxyphenylpiperidines, leur preparation et leurs applications therapeutiques | |
FR2391215A1 (fr) | Nouvelles imidazoazines et imidazodiazines, leur preparation et leur application en tant que medicaments | |
FR2354761A1 (fr) | Acides n-aryl-anthraniliques, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits acides anthraniliques | |
FR2442836A1 (fr) | 1,2,4,5-tetra-alkyl-4-arylpiperidines, leur preparation et leur utilisation therapeutique | |
FR2402473A1 (fr) | Agents tensio-actifs constitues d'ethoxylats d'aminopropoxyalcanes | |
FR2422404A1 (fr) | Compositions pharmaceutiques a base de 2,4-diamino-5-benzylpyrimidine et d'un sulfamide; et leur preparation | |
FR2431515A1 (fr) | Composition de copolycarbonate-phenolphtaleine | |
FR2446829A1 (fr) | Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant | |
FR2388794A1 (fr) | Isoindolines et leur preparation | |
FR2385707A1 (fr) | 3-amino-6,7-dialcoxy-1h-1,2,4-benzothiadiazine-1-oxydes 1-substitues et leur utilisation comme medicaments | |
FR2453169A1 (fr) | Composes de pyranone substitues en position 6 et leur utilisation comme produits pharmaceutiques | |
FR2453648A1 (fr) | Nouvelles compositions pharmaceutiques a base d'une quinazolinone exercant une action analgesique et d'un agent myotonolytique | |
FR2446279A1 (fr) | Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs | |
FR2399248A2 (fr) | Nouvelles solutions pharmaceutiques stables et leur preparation | |
FR2378518A1 (fr) | Nouveaux medicaments a base de derives de tetrahydrodibenzopyranne | |
FR2359116A1 (fr) | N-alkyldiphenylamines | |
FR2414513A1 (fr) | ||
FR2401167A1 (fr) | Derives de thienothiazine utiles comme medicaments | |
FR2395751A1 (fr) | Compositions odoriferantes et/ou aromatisantes | |
FR2446833A1 (fr) | Octahydro-2h-pyrrolo(3,4-g)quinoleines et leur utilisation therapeutiques | |
FR2442236A1 (fr) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |