DK143339C - Analogifremgangsmaade til fremstilling af 6-oxo-7,7-disubstitueret-1,2,7,8-tetrahydro-6h-indeno(5,4-b)furan-2-carboxylsyrer - Google Patents

Analogifremgangsmaade til fremstilling af 6-oxo-7,7-disubstitueret-1,2,7,8-tetrahydro-6h-indeno(5,4-b)furan-2-carboxylsyrer

Info

Publication number
DK143339C
DK143339C DK56076A DK56076A DK143339C DK 143339 C DK143339 C DK 143339C DK 56076 A DK56076 A DK 56076A DK 56076 A DK56076 A DK 56076A DK 143339 C DK143339 C DK 143339C
Authority
DK
Denmark
Prior art keywords
indeno
disubstituted
furan
tetrahydro
oxo
Prior art date
Application number
DK56076A
Other languages
Danish (da)
English (en)
Other versions
DK56076A (da
DK143339B (da
Inventor
Jr E J Cragoe
Jr O W Woltersdorf
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK56076A publication Critical patent/DK56076A/da
Publication of DK143339B publication Critical patent/DK143339B/da
Application granted granted Critical
Publication of DK143339C publication Critical patent/DK143339C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK56076A 1975-02-24 1976-02-11 Analogifremgangsmaade til fremstilling af 6-oxo-7,7-disubstitueret-1,2,7,8-tetrahydro-6h-indeno(5,4-b)furan-2-carboxylsyrer DK143339C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55240275 1975-02-24
US05/552,402 US3984552A (en) 1975-02-24 1975-02-24 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids

Publications (3)

Publication Number Publication Date
DK56076A DK56076A (da) 1976-08-25
DK143339B DK143339B (da) 1981-08-10
DK143339C true DK143339C (da) 1981-12-07

Family

ID=24205173

Family Applications (1)

Application Number Title Priority Date Filing Date
DK56076A DK143339C (da) 1975-02-24 1976-02-11 Analogifremgangsmaade til fremstilling af 6-oxo-7,7-disubstitueret-1,2,7,8-tetrahydro-6h-indeno(5,4-b)furan-2-carboxylsyrer

Country Status (15)

Country Link
US (1) US3984552A (es)
JP (1) JPS6154794B2 (es)
AU (1) AU500514B2 (es)
BE (1) BE838828A (es)
CA (1) CA1072972A (es)
CH (1) CH617689A5 (es)
DE (1) DE2607305C2 (es)
DK (1) DK143339C (es)
ES (1) ES445380A1 (es)
FR (1) FR2301246A1 (es)
GB (1) GB1497382A (es)
HU (1) HU177120B (es)
NL (1) NL7601295A (es)
SE (1) SE425605B (es)
ZA (1) ZA761046B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394385A (en) * 1980-11-21 1983-07-19 Merck & Co., Inc. Treatment of gray matter edema
US6890363B1 (en) * 1999-05-24 2005-05-10 Showa Denko K.K. Solid electrolytic capacitor and method for producing the same
US6858615B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6858614B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
KR101391746B1 (ko) 2011-06-16 2014-05-12 카톨리에케 유니버시타이트 로이벤 케이.유. 로이벤 알 앤 디 인다논 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
KR101630243B1 (ko) 2012-12-14 2016-06-15 한국화학연구원 신규한 화합물, 이의 약학적으로 허용가능한 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
AU2013363218B2 (en) 2012-12-17 2018-03-15 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
CN115916763A (zh) 2020-04-20 2023-04-04 诺华股份有限公司 抗病毒素1,3-二氧代茚化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931239A (en) * 1974-04-03 1976-01-06 Merck & Co., Inc. 6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids

Also Published As

Publication number Publication date
BE838828A (fr) 1976-08-23
SE7601422L (sv) 1976-08-25
ZA761046B (en) 1977-03-30
DE2607305C2 (de) 1987-04-30
FR2301246B1 (es) 1980-06-20
JPS51110558A (es) 1976-09-30
JPS6154794B2 (es) 1986-11-25
ES445380A1 (es) 1977-10-01
DE2607305A1 (de) 1976-09-02
CH617689A5 (es) 1980-06-13
AU500514B2 (en) 1979-05-24
DK56076A (da) 1976-08-25
US3984552A (en) 1976-10-05
FR2301246A1 (fr) 1976-09-17
CA1072972A (en) 1980-03-04
NL7601295A (nl) 1976-08-26
DK143339B (da) 1981-08-10
SE425605B (sv) 1982-10-18
HU177120B (en) 1981-07-28
GB1497382A (en) 1978-01-12
AU1117976A (en) 1977-08-25

Similar Documents

Publication Publication Date Title
DK298176A (da) Fremgangsmade til fremstilling af 1,4-dihydropyrinderivater
DK143708C (da) Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16alfa-methyl-pregna-1,4-dien-3,20-dion-forbindelser
DK247076A (da) Fremgangsmade til fremstilling af sur protease
DK143339C (da) Analogifremgangsmaade til fremstilling af 6-oxo-7,7-disubstitueret-1,2,7,8-tetrahydro-6h-indeno(5,4-b)furan-2-carboxylsyrer
DK159787C (da) Fremgangsmaade til fremstilling af 3',4'-dideoxykanamycin b
DK164376A (da) Fremgangsmade til fremstilling af 3,4-dihydrospiro-2h-1,3-benzoxaziner
DK139267B (da) Fremgangsmaade til fremstilling af 4-androsten3,17-dionderivater
DK324776A (da) Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler
DK153489C (da) Analogifremgangsmaade til fremstilling af 7-aminothiazolylacetamidocephalosporansyrederivater
DK150484C (da) Analogifremgangsmaade til fremstilling af 4-amino-3-thiophencarboxylsyrederivater
DK143757C (da) Analogifremgangsmaade til fremstilling af 16,16-disubstituerede 3-oxoandrostener
DK305876A (da) Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid
DK138743B (da) Analogifremgangsmåde til fremstilling af 1-oxo-1H-pyrimido (1,2-a)quinolin-2-carboxylsyre-forbindelser.
DK147973C (da) Analogifremgangsmaade til fremstilling af 1,4-diphenyl-3-pyrazolyleddikesyrer
DK143281C (da) Fremgangsmaade til fremstilling af phosphitchlorider
DK143137C (da) Fremgangsmaade til fremstilling af phosphitchlorider
DK154888C (da) Analogifremgangsmaade til fremstilling af 6-substituerede-6-methoxypenicillansyrederivater
DK219776A (da) Fremgangsmade til fremstilling af 1,2-benzothiazin-oxadiazolforbindelse
DK143346C (da) Fremgangsmaade til fremstilling af 0,0-dialkylthionophosphorsyrechlorider
DK526476A (da) Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner
DK475376A (da) Fremgangsmade til fremstilling af 2,9-dioxatricyclo/4,3,1,03,7/decan-forbindelser
DK150543C (da) Analogifremgangsmaade til fremstilling af 4-phenyl-3-oxo-1,2,4-oxadiazinderivater
DK29276A (da) Fremgangsmade til fremstilling af 8-bromothieno-triazolo-1,4-diazepiner
DK280376A (da) Fremgangsmade til fremstilling af 1-acyl-1,2,3,4-tetrahydro-6-quinoliner
DK146593C (da) Analogifremgangsmaade til fremstilling af fluorprostaglandiner

Legal Events

Date Code Title Description
PBP Patent lapsed