DK141660C - Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive bis-phenoxyalkanolaminer eller fysiologisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive bis-phenoxyalkanolaminer eller fysiologisk acceptable syreadditionssalte deraf

Info

Publication number
DK141660C
DK141660C DK117273A DK117273A DK141660C DK 141660 C DK141660 C DK 141660C DK 117273 A DK117273 A DK 117273A DK 117273 A DK117273 A DK 117273A DK 141660 C DK141660 C DK 141660C
Authority
DK
Denmark
Prior art keywords
phenoxyalkanolamines
racemic
analogue
preparation
acid addition
Prior art date
Application number
DK117273A
Other languages
English (en)
Other versions
DK141660B (da
Inventor
H Koeppe
H Staehle
W Kummer
G Muacevic
W Traunecker
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722210620 external-priority patent/DE2210620C2/de
Priority claimed from DE19722260620 external-priority patent/DE2260620A1/de
Priority claimed from DE19722260444 external-priority patent/DE2260444A1/de
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK141660B publication Critical patent/DK141660B/da
Application granted granted Critical
Publication of DK141660C publication Critical patent/DK141660C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK117273A 1935-11-15 1973-03-05 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive bis-phenoxyalkanolaminer eller fysiologisk acceptable syreadditionssalte deraf DK141660C (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
FR157273X 1935-11-15
FR157273X 1935-11-15
DE19722210620 DE2210620C2 (de) 1972-03-06 1972-03-06 Bis-Phenoxypropanolamine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2210620 1972-03-06
DE19722260620 DE2260620A1 (de) 1972-12-11 1972-12-11 Messerturbomuehle
DE2260620 1972-12-11
DE19722260444 DE2260444A1 (de) 1972-12-11 1972-12-11 Neue bis-alkanol-aminderivate, deren saeureadditionssalze, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2260444 1972-12-11

Publications (2)

Publication Number Publication Date
DK141660B DK141660B (da) 1980-05-19
DK141660C true DK141660C (da) 1980-10-20

Family

ID=27431439

Family Applications (1)

Application Number Title Priority Date Filing Date
DK117273A DK141660C (da) 1935-11-15 1973-03-05 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive bis-phenoxyalkanolaminer eller fysiologisk acceptable syreadditionssalte deraf

Country Status (12)

Country Link
US (1) US3888898A (da)
JP (1) JPS5825657B2 (da)
AT (5) AT326107B (da)
CH (7) CH605633A5 (da)
DK (1) DK141660C (da)
ES (7) ES412333A1 (da)
FI (1) FI59391C (da)
FR (1) FR2175055B1 (da)
GB (1) GB1431341A (da)
NL (1) NL7303097A (da)
NO (1) NO137049C (da)
SE (1) SE413402B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975539A (en) * 1935-11-15 1976-08-17 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing an N,N-bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamine and method of use
US4024281A (en) * 1972-05-26 1977-05-17 Smithkline Corporation N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines
US4041074A (en) * 1973-07-19 1977-08-09 Imperial Chemical Industries Limited 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
US4029783A (en) * 1973-08-03 1977-06-14 Boehringer Mannheim G.M.B.H. N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
US4139623A (en) * 1974-05-14 1979-02-13 C-G Corp. Cyclic-substituted derivatives of 1-amino-2-propanol
DE2555920C2 (de) * 1974-12-24 1983-12-15 Rohm and Haas Co., 19105 Philadelphia, Pa. Mehrzweckzusatz für Benzin und eine ihn enthaltende Kraftstoffmischung
US4013777A (en) * 1975-08-22 1977-03-22 Smithkline Corporation Bis-phenoxypropanolamines
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
IE47053B1 (en) * 1977-05-23 1983-12-14 Ici Ltd Cardiac stimulants
US4163053A (en) * 1977-12-27 1979-07-31 Schering Corporation Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
US4351848A (en) * 1978-03-16 1982-09-28 Drug Science Foundation 1-((1-Methylethyl)amino)-3-(((4-alkylthio)1-naphthalenyl)oxy)-2-propanol
DE3068678D1 (en) * 1979-08-10 1984-08-30 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
US4342783A (en) * 1980-06-30 1982-08-03 Synthelabo Anti-glaucoma agent
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US4751278A (en) * 1987-04-29 1988-06-14 Ciba-Geigy Corporation Adducts of monoepoxides and selected diamines
US6001824A (en) * 1988-02-08 1999-12-14 The Trustees Of Columbia University Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
WO1989007098A1 (en) * 1988-02-08 1989-08-10 The Trustees Of Columbia University In The City Of Butyrl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
DE69635460T2 (de) * 1995-06-26 2006-08-10 Chelator Llc, Concord Methode zur Hemmung des Wachstums von Bakterien oder Pilzen mit einem Komplexbildner

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
DE1901549B2 (de) * 1968-09-30 1978-04-13 Veb Fahlberg-List, Chemische Und Pharmazeutische Fabriken, Ddr 3011 Magdeburg N,N'-Bis-[3-(2'-äthoxyphenoxy)-2-hydroxypropyl] -ethylendiamin, Verfahren zu dessen Herstellung und Arzneimittel auf dessen Basis
BE754604A (fr) * 1969-08-08 1971-02-08 Boehringer Sohn Ingelheim Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels

Also Published As

Publication number Publication date
CH605634A5 (da) 1978-10-13
ES431265A1 (es) 1976-10-16
AU5294473A (en) 1974-09-12
DK141660B (da) 1980-05-19
ES431262A1 (es) 1977-02-01
CH605633A5 (da) 1978-10-13
SE413402B (sv) 1980-05-27
ES431266A1 (es) 1976-10-16
FR2175055B1 (da) 1976-08-13
AT323131B (de) 1975-06-25
ATA157273A (de) 1975-02-15
FR2175055A1 (da) 1973-10-19
ES412333A1 (es) 1976-01-01
CH599924A5 (da) 1978-06-15
FI59391C (fi) 1981-08-10
JPS48103532A (da) 1973-12-25
AT323132B (de) 1975-06-25
GB1431341A (en) 1976-04-07
ES431261A1 (es) 1977-02-01
FI59391B (fi) 1981-04-30
ES431263A1 (es) 1977-02-01
AT325022B (de) 1975-09-25
ES431264A1 (es) 1976-10-16
CH605630A5 (da) 1978-10-13
AT326107B (de) 1975-11-25
JPS5825657B2 (ja) 1983-05-28
NL7303097A (da) 1973-09-10
CH601182A5 (da) 1978-06-30
NO137049B (no) 1977-09-12
AT325023B (de) 1975-09-25
CH605631A5 (da) 1978-10-13
US3888898A (en) 1975-06-10
CH605632A5 (da) 1978-10-13
NO137049C (no) 1977-12-21

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PBP Patent lapsed