DK1410019T3 - Assay for kardiovaskulær sikkerhed - Google Patents

Assay for kardiovaskulær sikkerhed

Info

Publication number
DK1410019T3
DK1410019T3 DK02762316T DK02762316T DK1410019T3 DK 1410019 T3 DK1410019 T3 DK 1410019T3 DK 02762316 T DK02762316 T DK 02762316T DK 02762316 T DK02762316 T DK 02762316T DK 1410019 T3 DK1410019 T3 DK 1410019T3
Authority
DK
Denmark
Prior art keywords
cardiovascular safety
kits
safety assay
cardiotoxicity
assays
Prior art date
Application number
DK02762316T
Other languages
English (en)
Inventor
Godelieve Irma Christin Heylen
Mirek Jurzak
Assouw Henricus Petrus Mar Van
Cornelus Gerardus Mari Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1410019T3 publication Critical patent/DK1410019T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK02762316T 2001-07-13 2002-07-02 Assay for kardiovaskulær sikkerhed DK1410019T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202689 2001-07-13

Publications (1)

Publication Number Publication Date
DK1410019T3 true DK1410019T3 (da) 2006-03-06

Family

ID=8180635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02762316T DK1410019T3 (da) 2001-07-13 2002-07-02 Assay for kardiovaskulær sikkerhed

Country Status (14)

Country Link
US (3) US20040161805A1 (da)
EP (1) EP1410019B1 (da)
JP (1) JP4570870B2 (da)
CN (1) CN1276254C (da)
AT (1) ATE308046T1 (da)
AU (1) AU2002328312B8 (da)
CA (1) CA2450581C (da)
DE (1) DE60206923T2 (da)
DK (1) DK1410019T3 (da)
ES (1) ES2252505T3 (da)
HK (1) HK1070693A1 (da)
IL (2) IL159819A0 (da)
NZ (1) NZ529496A (da)
WO (1) WO2003006988A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0302775D0 (sv) * 2003-10-20 2003-10-20 Astrazeneca Ab Chemical compound and assay
US7396524B2 (en) * 2005-08-02 2008-07-08 Main Line Health Heart Center Methods for screening compounds for proarrhythmic risk and antiarrhythmic efficacy
US9820888B2 (en) 2006-09-26 2017-11-21 Smith & Nephew, Inc. Wound dressing
GB0902368D0 (en) 2009-02-13 2009-04-01 Smith & Nephew Wound packing
US9421132B2 (en) 2011-02-04 2016-08-23 University Of Massachusetts Negative pressure wound closure device
EP3932327A1 (en) 2011-02-04 2022-01-05 University Of Massachusetts Negative pressure wound closure device
JP6382185B2 (ja) 2012-05-22 2018-08-29 スミス アンド ネフュー ピーエルシーSmith & Nephew Public Limited Company 創傷治療のための装置および方法
EP2852419B1 (en) 2012-05-22 2019-11-20 Smith & Nephew plc Wound closure device
US10117782B2 (en) 2012-05-24 2018-11-06 Smith & Nephew, Inc. Devices and methods for treating and closing wounds with negative pressure
RU2015104581A (ru) 2012-07-16 2016-09-10 Смит Энд Нефью, Инк. Устройство для закрытия раны с использованием отрицательного давления
CA2902776C (en) 2013-03-13 2023-03-07 Smith & Nephew Inc. Wound treatment apparatus and use thereof
US10159771B2 (en) 2013-03-14 2018-12-25 Smith & Nephew Plc Compressible wound fillers and systems and methods of use in treating wounds with negative pressure
AU2016254119A1 (en) 2015-04-29 2017-10-05 Smith & Nephew Inc. Negative pressure wound closure device
US10575991B2 (en) 2015-12-15 2020-03-03 University Of Massachusetts Negative pressure wound closure devices and methods
US10814049B2 (en) 2015-12-15 2020-10-27 University Of Massachusetts Negative pressure wound closure devices and methods
CA3089957C (en) * 2017-02-04 2024-01-23 AnaBios Corporation System and methods for predicting drug-induced inotropic and pro-arrhythmia risk
WO2020124038A1 (en) 2018-12-13 2020-06-18 University Of Massachusetts Negative pressure wound closure devices and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
WO2000070079A1 (en) * 1999-05-13 2000-11-23 Ortho-Mcneil Pharmaceutical, Inc. High throughput assay for modulators of nuclear receptors
WO2002042735A2 (en) * 2000-10-30 2002-05-30 Vanderbuilt University Human kcr1 regulation of herg potassium channel block

Also Published As

Publication number Publication date
CA2450581A1 (en) 2003-01-23
ES2252505T3 (es) 2006-05-16
WO2003006988A1 (en) 2003-01-23
AU2002328312B2 (en) 2006-12-14
EP1410019A1 (en) 2004-04-21
JP4570870B2 (ja) 2010-10-27
ATE308046T1 (de) 2005-11-15
EP1410019B1 (en) 2005-10-26
DE60206923T2 (de) 2006-07-20
HK1070693A1 (en) 2005-06-24
IL159819A0 (en) 2004-06-20
US20110076696A1 (en) 2011-03-31
AU2002328312B8 (en) 2007-02-15
CN1541334A (zh) 2004-10-27
NZ529496A (en) 2005-09-30
AU2002328312A1 (en) 2003-01-29
US20040161805A1 (en) 2004-08-19
CN1276254C (zh) 2006-09-20
CA2450581C (en) 2010-11-02
JP2005501037A (ja) 2005-01-13
US7820453B2 (en) 2010-10-26
US20080193924A1 (en) 2008-08-14
DE60206923D1 (de) 2005-12-01
IL159819A (en) 2010-05-31

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