DK1410019T3 - Assay for kardiovaskulær sikkerhed - Google Patents

Assay for kardiovaskulær sikkerhed

Info

Publication number
DK1410019T3
DK1410019T3 DK02762316T DK02762316T DK1410019T3 DK 1410019 T3 DK1410019 T3 DK 1410019T3 DK 02762316 T DK02762316 T DK 02762316T DK 02762316 T DK02762316 T DK 02762316T DK 1410019 T3 DK1410019 T3 DK 1410019T3
Authority
DK
Denmark
Prior art keywords
cardiovascular safety
kits
safety assay
cardiotoxicity
assays
Prior art date
Application number
DK02762316T
Other languages
English (en)
Inventor
Godelieve Irma Christin Heylen
Mirek Jurzak
Assouw Henricus Petrus Mar Van
Cornelus Gerardus Mari Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1410019T3 publication Critical patent/DK1410019T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Sampling And Sample Adjustment (AREA)
DK02762316T 2001-07-13 2002-07-02 Assay for kardiovaskulær sikkerhed DK1410019T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202689 2001-07-13

Publications (1)

Publication Number Publication Date
DK1410019T3 true DK1410019T3 (da) 2006-03-06

Family

ID=8180635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02762316T DK1410019T3 (da) 2001-07-13 2002-07-02 Assay for kardiovaskulær sikkerhed

Country Status (14)

Country Link
US (3) US20040161805A1 (da)
EP (1) EP1410019B1 (da)
JP (1) JP4570870B2 (da)
CN (1) CN1276254C (da)
AT (1) ATE308046T1 (da)
AU (1) AU2002328312B8 (da)
CA (1) CA2450581C (da)
DE (1) DE60206923T2 (da)
DK (1) DK1410019T3 (da)
ES (1) ES2252505T3 (da)
HK (1) HK1070693A1 (da)
IL (2) IL159819A0 (da)
NZ (1) NZ529496A (da)
WO (1) WO2003006988A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0302775D0 (sv) * 2003-10-20 2003-10-20 Astrazeneca Ab Chemical compound and assay
US7396524B2 (en) * 2005-08-02 2008-07-08 Main Line Health Heart Center Methods for screening compounds for proarrhythmic risk and antiarrhythmic efficacy
US9820888B2 (en) 2006-09-26 2017-11-21 Smith & Nephew, Inc. Wound dressing
GB0902368D0 (en) 2009-02-13 2009-04-01 Smith & Nephew Wound packing
WO2012106590A2 (en) 2011-02-04 2012-08-09 University Of Massachusetts Negative pressure wound closure device
US9421132B2 (en) 2011-02-04 2016-08-23 University Of Massachusetts Negative pressure wound closure device
CN104661601B (zh) 2012-05-22 2018-06-22 史密夫及内修公开有限公司 用于伤口治疗的设备和方法
MX2014014265A (es) 2012-05-22 2015-06-23 Smith & Nephew Dispositivo para cierre de heridas.
WO2013175309A1 (en) 2012-05-24 2013-11-28 Smith & Nephew Plc Devices and methods for treating and closing wounds with negative pressure
US9962295B2 (en) 2012-07-16 2018-05-08 Smith & Nephew, Inc. Negative pressure wound closure device
AU2014248519B2 (en) 2013-03-13 2018-12-20 Smith & Nephew Inc. Negative pressure wound closure device and systems and methods of use in treating wounds with negative pressure
US10159771B2 (en) 2013-03-14 2018-12-25 Smith & Nephew Plc Compressible wound fillers and systems and methods of use in treating wounds with negative pressure
EP3288509B1 (en) 2015-04-29 2022-06-29 Smith & Nephew, Inc Negative pressure wound closure device
US10575991B2 (en) 2015-12-15 2020-03-03 University Of Massachusetts Negative pressure wound closure devices and methods
US10814049B2 (en) 2015-12-15 2020-10-27 University Of Massachusetts Negative pressure wound closure devices and methods
JP6940920B2 (ja) * 2017-02-04 2021-09-29 アナバイオス コーポレーション 医薬誘発性の変力作用および不整脈誘発のリスクを予測するためのシステムおよび方法
WO2020124038A1 (en) 2018-12-13 2020-06-18 University Of Massachusetts Negative pressure wound closure devices and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
WO2000070079A1 (en) * 1999-05-13 2000-11-23 Ortho-Mcneil Pharmaceutical, Inc. High throughput assay for modulators of nuclear receptors
WO2002042735A2 (en) * 2000-10-30 2002-05-30 Vanderbuilt University Human kcr1 regulation of herg potassium channel block

Also Published As

Publication number Publication date
HK1070693A1 (en) 2005-06-24
WO2003006988A1 (en) 2003-01-23
AU2002328312B8 (en) 2007-02-15
US20110076696A1 (en) 2011-03-31
CN1276254C (zh) 2006-09-20
CN1541334A (zh) 2004-10-27
ES2252505T3 (es) 2006-05-16
EP1410019A1 (en) 2004-04-21
US20080193924A1 (en) 2008-08-14
AU2002328312B2 (en) 2006-12-14
US7820453B2 (en) 2010-10-26
CA2450581C (en) 2010-11-02
IL159819A0 (en) 2004-06-20
IL159819A (en) 2010-05-31
CA2450581A1 (en) 2003-01-23
JP2005501037A (ja) 2005-01-13
DE60206923D1 (de) 2005-12-01
ATE308046T1 (de) 2005-11-15
JP4570870B2 (ja) 2010-10-27
NZ529496A (en) 2005-09-30
US20040161805A1 (en) 2004-08-19
AU2002328312A1 (en) 2003-01-29
EP1410019B1 (en) 2005-10-26
DE60206923T2 (de) 2006-07-20

Similar Documents

Publication Publication Date Title
HK1070693A1 (en) Assays and kits for the screening of test compounds
WO2007035633A3 (en) Screening assays and methods
ATE515702T1 (de) Verfahren, mixturen, kits und zusammensetzungen bezüglich der analytbestimmung
NO20081374L (no) Analyser og fremgangsmater som benytter biomarkorer
DK0820522T3 (da) Assays og indretninger til detektering af ekstrahepatisk galdeatresi
DE602005015559D1 (de) Pharmakodynamische tests mit durchflusszytometrie
DK1540010T3 (da) Anvendelse af biomarkører til påvisning af ovariecancer
AU2003293704A8 (en) Methods and kits for assays of rapid screening of diabetes
DK1071809T3 (da) Multiparameter FACS test til påvisning af ændringer i cellulære parametre
ES2138628T3 (es) Metodo para la determinacion inmunologica de un componente de una muestra.
ATE351921T1 (de) Verfahren für fluoreszenzerkennungstest
WO2006088700A3 (en) Human ring specific bnp antibodies
MX2009006205A (es) Inmunoensayo de multiples analitos.
DK1858921T3 (da) Fotoproteiner med forbedret bioluminescens og anvendelse af disse som intracellulære calciumindikatorer
MX2009013009A (es) Inmunoensayos de alta sensibilidad y kits para la determinacion de peptidos y proteinas de interes biologico.
DE60325107D1 (de) Verfahren und kit zum quantitativen und/oder qualitativen nachweis von komponenten in einer probe
DE602006014120D1 (de) Kolloidale metallkonjugate
BR0212265B1 (pt) Método para a determinação de pelo menos três analitos, composição, kit para a determinação de pelo menos três analitos e uso de pelo menos três parceiros de ligação para a determinação de pelo menos três analitos em uma amostra
BR0215853A (pt) Testes de bioequivalência para formulações contendo ferro
DK0902286T3 (da) Immunanalyse med anvendelse af to inkubationer med mærket antigen
FR2853077B1 (fr) Procedes immunochromatographiques en phase solide
DE60329861D1 (de) Neue, auf der antigen-antikörper-reaktion beruhende sondenplatte sowie reagenzienkit und verfahren mit verwendung der sondenplatte
BR0314166A (pt) Teste de hcv
SE0301058D0 (sv) Method and kit for cell analyte assay
AU2003242106A8 (en) Detection kit, assay plate to be used therein, detection method, evaluation method, polyclonal antibody of frog vitellogenin and procss for producing the same