DK1407784T3 - Antitumormidler - Google Patents

Antitumormidler

Info

Publication number
DK1407784T3
DK1407784T3 DK02738789.3T DK02738789T DK1407784T3 DK 1407784 T3 DK1407784 T3 DK 1407784T3 DK 02738789 T DK02738789 T DK 02738789T DK 1407784 T3 DK1407784 T3 DK 1407784T3
Authority
DK
Denmark
Prior art keywords
tublin
antitumor
polymerization inhibitor
antitumor agents
activity
Prior art date
Application number
DK02738789.3T
Other languages
English (en)
Inventor
Yukio Nihei
Yoshihiro Morinaga
Manabu Suzuki
Yasuyo Suga
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1407784T3 publication Critical patent/DK1407784T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
DK02738789.3T 2001-06-25 2002-06-24 Antitumormidler DK1407784T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001191067 2001-06-25
PCT/JP2002/006260 WO2003000290A1 (fr) 2001-06-25 2002-06-24 Agents antitumoraux

Publications (1)

Publication Number Publication Date
DK1407784T3 true DK1407784T3 (da) 2011-02-28

Family

ID=19029748

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02738789.3T DK1407784T3 (da) 2001-06-25 2002-06-24 Antitumormidler

Country Status (10)

Country Link
US (2) US20040192621A1 (da)
EP (1) EP1407784B1 (da)
JP (1) JP4779298B2 (da)
CN (2) CN101816794A (da)
AT (1) ATE489080T1 (da)
DE (1) DE60238408D1 (da)
DK (1) DK1407784T3 (da)
ES (1) ES2356986T3 (da)
PT (1) PT1407784E (da)
WO (1) WO2003000290A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU756699B2 (en) 1996-12-03 2003-01-23 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
PT1068870E (pt) * 1998-04-03 2006-10-31 Ajinomoto Kk Agentes antitumorais
WO2004018478A2 (en) 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
CN101538253B (zh) * 2008-03-21 2012-03-21 江苏豪森医药集团连云港宏创医药有限公司 一种制备瑞格列奈中间体的方法
FR2945210B1 (fr) 2009-05-07 2011-07-01 Sanofi Aventis Combinaison antitumorale comprenant l'ave8062 et le sorafenib
FR2953518B1 (fr) 2009-12-03 2012-01-20 Sanofi Aventis Procede de preparation d'un derive de combretastatine
EP2407161A1 (en) 2010-07-13 2012-01-18 Sanofi An antitumoral combination comprising ombrabulin and bevacizumab
EP2638047B1 (en) * 2010-11-11 2014-07-16 Council of Scientific and Industrial Research "substituted 4-beta-acrylamidopodophyllotoxin congeners as antitumour antibiotics and the process for preparation thereof"
FR2968557A1 (fr) 2010-12-09 2012-06-15 Sanofi Aventis Combinaison antitumorale comprenant un derive de la famille des combretastatines et le cetuximab
FR2978662A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cisplatine, associee a la radiotherapie
FR2978663A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cetuximab, associee a la radiotherapie
CN102391164B (zh) * 2011-09-23 2014-08-13 中南大学 一种二芳基硫醚化合物、制备方法及其抗肿瘤应用
CN104003918A (zh) * 2011-09-23 2014-08-27 中南大学 一种二芳基硫醚化合物、制备方法及其抗肿瘤应用
CN103396376B (zh) * 2013-07-31 2016-08-10 杨文茂 一种抗菌抗癌活性化合物
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
CN112272565A (zh) * 2018-04-27 2021-01-26 西雅图儿童医院以西雅图儿童研究机构名义经营 使用慢病毒基因构建体的递送的体内基因疗法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US93540A (en) * 1869-08-10 Improvement in baster-guide for sewing-machines
US193434A (en) * 1877-07-24 Improvement in measuring devices for filling cartridges
GB1272841A (en) * 1969-01-23 1972-05-03 Leo Ab New corticoid steroid compounds of cytostatic interest
US5929059A (en) * 1991-01-19 1999-07-27 Smithkline Beecham P.L.C. Pharmaceutical compositions containing granisetron and dexamethasone
TW325458B (en) 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5731353A (en) * 1993-09-08 1998-03-24 Ajinomoto Co., Inc. Stilbene derivatives and pharmaceutical compositions containing them
US5561122A (en) 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
JP3163391B2 (ja) 1995-03-07 2001-05-08 味の素株式会社 スチルベン誘導体及びそれを含有する制癌剤
TW334418B (en) * 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
EP0841914A2 (en) * 1995-08-03 1998-05-20 The Procter & Gamble Company Use of griseofulvin for inhibiting the growth of cancers
JP4420472B2 (ja) * 1996-04-15 2010-02-24 旭化成株式会社 薬物複合体
IE960761A1 (en) * 1996-10-31 1998-05-06 Univ Dublin City Combinations for use in increasing the potency of a¹substrate for multidrug resistance related protein
US5900429A (en) * 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
PT1068870E (pt) * 1998-04-03 2006-10-31 Ajinomoto Kk Agentes antitumorais

Also Published As

Publication number Publication date
EP1407784A4 (en) 2006-12-13
CN1543356A (zh) 2004-11-03
CN101816794A (zh) 2010-09-01
WO2003000290A1 (fr) 2003-01-03
JPWO2003000290A1 (ja) 2004-10-07
US20100216755A1 (en) 2010-08-26
CN1543356B (zh) 2011-09-28
EP1407784B1 (en) 2010-11-24
JP4779298B2 (ja) 2011-09-28
ATE489080T1 (de) 2010-12-15
ES2356986T3 (es) 2011-04-15
PT1407784E (pt) 2011-03-03
EP1407784A1 (en) 2004-04-14
DE60238408D1 (de) 2011-01-05
US20040192621A1 (en) 2004-09-30

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