ATE489080T1 - Antitumorale mittel - Google Patents

Antitumorale mittel

Info

Publication number
ATE489080T1
ATE489080T1 AT02738789T AT02738789T ATE489080T1 AT E489080 T1 ATE489080 T1 AT E489080T1 AT 02738789 T AT02738789 T AT 02738789T AT 02738789 T AT02738789 T AT 02738789T AT E489080 T1 ATE489080 T1 AT E489080T1
Authority
AT
Austria
Prior art keywords
tublin
polymerization inhibitor
antitumor
activity
antiinflammatory
Prior art date
Application number
AT02738789T
Other languages
English (en)
Inventor
Yukio Nihei
Yoshihiro Morinaga
Manabu Suzuki
Yasuyo Suga
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE489080T1 publication Critical patent/ATE489080T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02738789T 2001-06-25 2002-06-24 Antitumorale mittel ATE489080T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001191067 2001-06-25
PCT/JP2002/006260 WO2003000290A1 (en) 2001-06-25 2002-06-24 Antitumor agents

Publications (1)

Publication Number Publication Date
ATE489080T1 true ATE489080T1 (de) 2010-12-15

Family

ID=19029748

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02738789T ATE489080T1 (de) 2001-06-25 2002-06-24 Antitumorale mittel

Country Status (10)

Country Link
US (2) US20040192621A1 (de)
EP (1) EP1407784B1 (de)
JP (1) JP4779298B2 (de)
CN (2) CN1543356B (de)
AT (1) ATE489080T1 (de)
DE (1) DE60238408D1 (de)
DK (1) DK1407784T3 (de)
ES (1) ES2356986T3 (de)
PT (1) PT1407784E (de)
WO (1) WO2003000290A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0977563B1 (de) 1996-12-03 2005-10-12 Sloan-Kettering Institute For Cancer Research Synthese von epothilonen, zwischenprodukte dazu, analoga und verwendungen davon
ES2267255T3 (es) * 1998-04-03 2007-03-01 Ajinomoto Co., Inc. Agentes antitumorales.
WO2004018478A2 (en) 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
CN101538253B (zh) * 2008-03-21 2012-03-21 江苏豪森医药集团连云港宏创医药有限公司 一种制备瑞格列奈中间体的方法
FR2945210B1 (fr) * 2009-05-07 2011-07-01 Sanofi Aventis Combinaison antitumorale comprenant l'ave8062 et le sorafenib
FR2953518B1 (fr) 2009-12-03 2012-01-20 Sanofi Aventis Procede de preparation d'un derive de combretastatine
EP2407161A1 (de) 2010-07-13 2012-01-18 Sanofi Antitumor-Kombination mit Ombrabulin und Bevacizumab
US8673969B2 (en) * 2010-11-11 2014-03-18 Council Of Scientific & Industrial Research Substituted 4-β-acrylamidopodophyllotoxin congeners as antitumour antibiotics and the process for preparation thereof
FR2968557A1 (fr) 2010-12-09 2012-06-15 Sanofi Aventis Combinaison antitumorale comprenant un derive de la famille des combretastatines et le cetuximab
FR2978663A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cetuximab, associee a la radiotherapie
FR2978662A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cisplatine, associee a la radiotherapie
CN104003918A (zh) * 2011-09-23 2014-08-27 中南大学 一种二芳基硫醚化合物、制备方法及其抗肿瘤应用
CN102391164B (zh) * 2011-09-23 2014-08-13 中南大学 一种二芳基硫醚化合物、制备方法及其抗肿瘤应用
CN103396376B (zh) * 2013-07-31 2016-08-10 杨文茂 一种抗菌抗癌活性化合物
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
CN112272565A (zh) * 2018-04-27 2021-01-26 西雅图儿童医院以西雅图儿童研究机构名义经营 使用慢病毒基因构建体的递送的体内基因疗法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US93540A (en) * 1869-08-10 Improvement in baster-guide for sewing-machines
US193434A (en) * 1877-07-24 Improvement in measuring devices for filling cartridges
GB1272841A (en) * 1969-01-23 1972-05-03 Leo Ab New corticoid steroid compounds of cytostatic interest
US5929059A (en) * 1991-01-19 1999-07-27 Smithkline Beecham P.L.C. Pharmaceutical compositions containing granisetron and dexamethasone
US5731353A (en) * 1993-09-08 1998-03-24 Ajinomoto Co., Inc. Stilbene derivatives and pharmaceutical compositions containing them
TW325458B (en) 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5561122A (en) 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
JP3163391B2 (ja) 1995-03-07 2001-05-08 味の素株式会社 スチルベン誘導体及びそれを含有する制癌剤
TW334418B (en) * 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
MX9800945A (es) * 1995-08-03 1998-04-30 Procter & Gamble Uso de griseofulvina para inhibir el crecimiento de canceres.
WO1997038727A1 (en) * 1996-04-15 1997-10-23 Asahi Kasei Kogyo Kabushiki Kaisha Medicament composite
IE960761A1 (en) * 1996-10-31 1998-05-06 Univ Dublin City Combinations for use in increasing the potency of a¹substrate for multidrug resistance related protein
US5900429A (en) * 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
ES2267255T3 (es) * 1998-04-03 2007-03-01 Ajinomoto Co., Inc. Agentes antitumorales.

Also Published As

Publication number Publication date
DE60238408D1 (de) 2011-01-05
WO2003000290A1 (en) 2003-01-03
CN1543356A (zh) 2004-11-03
JPWO2003000290A1 (ja) 2004-10-07
CN1543356B (zh) 2011-09-28
US20040192621A1 (en) 2004-09-30
DK1407784T3 (da) 2011-02-28
JP4779298B2 (ja) 2011-09-28
ES2356986T3 (es) 2011-04-15
EP1407784A4 (de) 2006-12-13
EP1407784B1 (de) 2010-11-24
EP1407784A1 (de) 2004-04-14
PT1407784E (pt) 2011-03-03
US20100216755A1 (en) 2010-08-26
CN101816794A (zh) 2010-09-01

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