DK140014B - Fremgangsmåde til fremstilling af 3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser. - Google Patents

Fremgangsmåde til fremstilling af 3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser.

Info

Publication number
DK140014B
DK140014B DK219274AA DK219274A DK140014B DK 140014 B DK140014 B DK 140014B DK 219274A A DK219274A A DK 219274AA DK 219274 A DK219274 A DK 219274A DK 140014 B DK140014 B DK 140014B
Authority
DK
Denmark
Prior art keywords
benzothiazine
carboxamide
dihydro
oxo
alkyl
Prior art date
Application number
DK219274AA
Other languages
Danish (da)
English (en)
Other versions
DK140014C (de
Inventor
Joseph George Lombardino
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK140014B publication Critical patent/DK140014B/da
Application granted granted Critical
Publication of DK140014C publication Critical patent/DK140014C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK219274AA 1973-04-23 1974-04-22 Fremgangsmåde til fremstilling af 3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser. DK140014B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00353607A US3853862A (en) 1973-04-23 1973-04-23 Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides

Publications (2)

Publication Number Publication Date
DK140014B true DK140014B (da) 1979-06-05
DK140014C DK140014C (de) 1979-11-05

Family

ID=23389837

Family Applications (1)

Application Number Title Priority Date Filing Date
DK219274AA DK140014B (da) 1973-04-23 1974-04-22 Fremgangsmåde til fremstilling af 3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser.

Country Status (21)

Country Link
US (3) US3853862A (de)
JP (1) JPS5760347B2 (de)
AR (1) AR205249A1 (de)
AT (1) AT333777B (de)
CA (1) CA1018525A (de)
CH (1) CH590257A5 (de)
CS (1) CS165311B2 (de)
DD (1) DD111079A5 (de)
DK (1) DK140014B (de)
ES (1) ES425398A1 (de)
FI (1) FI52087C (de)
GB (1) GB1414887A (de)
HU (1) HU170489B (de)
IE (1) IE39119B1 (de)
LU (1) LU69905A1 (de)
NL (1) NL7405413A (de)
PL (1) PL90468B1 (de)
RO (1) RO63727A (de)
SE (1) SE406467B (de)
SU (1) SU552030A3 (de)
YU (1) YU39152B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954786A (en) * 1974-04-19 1976-05-04 Pfizer Inc. Isoxazole intermediate compounds
US3925371A (en) * 1974-09-23 1975-12-09 Mcneilab Inc Benzothiazine-1,1-dioxides
US3900470A (en) * 1974-09-23 1975-08-19 Mcneilab Inc Esters of benzothiazine-1,1-dioxides derivatives
US3923801A (en) * 1974-09-23 1975-12-02 Mcneilab Inc Oxazinobenzothiazine 6,6-dioxides
US3891637A (en) * 1974-10-01 1975-06-24 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
US3892740A (en) * 1974-10-15 1975-07-01 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
US4100347A (en) * 1976-06-10 1978-07-11 Pfizer Inc. 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4217355A (en) * 1978-04-24 1980-08-12 Pfizer Inc. Amide therapeutic agents
JPS57140785A (en) * 1981-02-24 1982-08-31 Mitsui Toatsu Chem Inc Benzothiazine derivative, its preparation, and pharmaceutical composition containing the same
JPS5714589A (en) * 1980-06-27 1982-01-25 Mitsui Toatsu Chem Inc Benzothiazine derivative, its preparation and drug composition
US4289879A (en) * 1980-09-29 1981-09-15 Pfizer Inc. Synthetic method and intermediate for piroxicam
GT198276334A (es) * 1981-08-03 1984-01-10 Procedimiento e inter-medios para la produccion de carboxamidas de benzotiazina.
IN158333B (de) * 1981-08-03 1986-10-18 Pfizer
IN159273B (de) * 1981-10-05 1987-04-25 Pfizer
SU1306476A3 (ru) * 1982-06-17 1987-04-23 Пфайзер,Инк (Фирма) Способ получени 2-метил-3- @ -(2-пиридил)-карбамоил-3,4-дигидро-2 @ -1,2-бензтиазин-1,1-диоксида
US4483982A (en) * 1982-09-02 1984-11-20 Pfizer Inc. Processes for preparing piroxicam and intermediates leading thereto
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
JPS6243434U (de) * 1985-09-03 1987-03-16
JPH0629271B2 (ja) * 1988-03-09 1994-04-20 株式会社日本ハイポックス ベンゾチアジン―1,1―ジオキシド誘導体及びそれを含有する医薬組成物
WO1997046532A1 (en) * 1996-06-03 1997-12-11 Boehringer Ingelheim Pharmaceuticals, Inc. 2-benzyl-4-sulfonyl-4h-isoquinolin-1,3-diones and their use as anti-inflammatory agents
CA2423933A1 (en) 2000-10-17 2002-04-25 Applied Research Systems Ars Holding N.V. Pharmaceutically active sulfanilide derivatives
US6865910B2 (en) * 2001-12-05 2005-03-15 Emhart Glass S.A. Glass container forming machine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676188A (en) * 1950-12-16 1954-04-20 American Home Prod Acylated glycinamides
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US4062861A (en) * 1973-07-27 1977-12-13 Shionogi & Co., Ltd. 3-Isoxazolylurea derivatives
GB1498884A (en) * 1975-04-15 1978-01-25 Wyeth John & Brother Ltd Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives

Also Published As

Publication number Publication date
SE406467B (sv) 1979-02-12
RO63727A (fr) 1978-12-15
HU170489B (de) 1977-06-28
AT333777B (de) 1976-12-10
US3853862A (en) 1974-12-10
SU552030A3 (ru) 1977-03-25
USRE29668E (en) 1978-06-13
ATA327374A (de) 1976-04-15
IE39119L (en) 1974-10-23
CS165311B2 (de) 1975-12-22
CA1018525A (en) 1977-10-04
PL90468B1 (de) 1977-01-31
GB1414887A (en) 1975-11-19
ES425398A1 (es) 1976-05-16
IE39119B1 (en) 1978-08-02
JPS5760347B2 (de) 1982-12-18
CH590257A5 (de) 1977-07-29
DD111079A5 (de) 1975-01-20
YU39152B (en) 1984-06-30
LU69905A1 (de) 1974-11-21
FI52087B (de) 1977-02-28
NL7405413A (de) 1974-10-25
YU112174A (en) 1982-06-30
FI52087C (fi) 1977-06-10
DK140014C (de) 1979-11-05
JPS5012094A (de) 1975-02-07
USRE29669E (en) 1978-06-13
AR205249A1 (es) 1976-04-21

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